A5071704690- Immune Cell Function and Interaction
- T-cell and B-cell Immunology
- SARS-CoV-2 and COVID-19 Research
- Organic Light-Emitting Diodes Research
- Organic Electronics and Photovoltaics
- Immunotherapy and Immune Responses
- COVID-19 Clinical Research Studies
- vaccines and immunoinformatics approaches
- Rock Mechanics and Modeling
- Advancements in Battery Materials
- Dam Engineering and Safety
- Cancer Immunotherapy and Biomarkers
- Conducting polymers and applications
- Photosynthetic Processes and Mechanisms
- Advanced battery technologies research
- RNA modifications and cancer
- Supercapacitor Materials and Fabrication
- Landslides and related hazards
- GaN-based semiconductor devices and materials
- Luminescence and Fluorescent Materials
- Monoclonal and Polyclonal Antibodies Research
- Plant Stress Responses and Tolerance
- Virus-based gene therapy research
- SARS-CoV-2 detection and testing
- Advanced Battery Materials and Technologies
Guangxi University
2015-2025
Anhui Academy of Agricultural Sciences
2012-2024
Xinxiang Medical University
2024
Wuhan University
2017-2024
University of Colorado Denver
2019-2024
Peking University People's Hospital
2024
Peking University
2024
National Jewish Health
2019-2024
Rice Research Institute
2021-2024
Chinese People’s Liberation Army 263 hospital
2024
Numerous efforts have been devoted to boost the efficiency of thermally activated delayed fluorescence (TADF) devices; however, strategies suppress device roll-off are still in urgent need. Here, a general and effective approach TADF devices is proposed, that is, utilizing materials as hosts for emitters. Bearing small singlet–triplet splitting (ΔEST) with donor acceptor units, possess potential achieve matched frontier energy levels adjacent transporting layers, facilitating balanced charge...
Abstract White organic light‐emitting diodes (WOLEDs) with thermally activated delayed fluorophor sensitized fluorescence (TSF) have aroused wide attention, considering their potential for full exciton utilization without noble‐metal containing phosphors. However, performances of TSF‐WOLEDs a single‐emissive‐layer (SEL) still suffer from low and insufficient blue emission proper white balance. Here, by modulating Förster Dexter interactions in SEL‐TSF‐WOLEDs, high efficiencies, balanced...
The newly emerging variants of SARS-CoV-2 from South Africa (B.1.351/501Y.V2) and Brazil (P.1/501Y.V3) have led to a higher infection rate reinfection COVID-19 patients. We found that the mutations K417N, E484K, N501Y within receptor-binding domains (RBDs) virus could confer ~2-fold binding affinity human receptor, angiotensin converting enzyme 2 (ACE2), compared wildtype RBD. mutated version RBD also completely abolishes bamlanivimab, therapeutic antibody, in vitro. Detailed analysis shows...
A high triplet energy (T1) is usually taken as the prerequisite of good exciton confinement electron transporting materials (ETMs); however, there a tradeoff with large mobility and stability. Here, we demonstrated that can also be realized utilizing low-T1 ETM sterically shielding unit. Given short-range interaction Dexter transfer, steric side groups effectively hinder T1 emitters from being quenched by increasing intermolecular distance. Based on this concept, maximum external quantum...
The threshold voltage (V <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">TH</sub> ) instability of p-GaN/AlGaN/GaN HEMTs was investigated under forward gate stress. A unique bidirectional V shift (AV with the critical xmlns:xlink="http://www.w3.org/1999/xlink">G</sub> 6 observed. carrier transport mechanisms underlying AV were extensively through voltage-dependent, timeresolved, and temperature-dependentgate current. current is decomposed into...
Rational structure and morphology design are of great significance to realize excellent Na storage for advanced electrode materials in sodium-ion batteries (SIBs). Herein, a cube-like core/shell composite single MnS nanocubes (≈50 nm) encapsulated N, S co-doped carbon (MnS@NSC) with strong CSMn bond interactions is successfully prepared as outstanding anode material SIBs. The shell significantly restricts the expansion volume successive sodiation/desodiation processes, demonstrated by situ...
N-doping is an effective way to increase the electron conductivity of organic semiconductors and achieve ohmic cathode contacts in electronics. To avoid use difficult-to-handle highly reactive n-dopants, air-stable precursors are widely used nowadays, which could decompose release species a subtractive though always with unwanted even harmful byproducts during processing. Here, we show that metals, such as copper, silver gold, free electrons readily presence chelating ligands, irreversible...
This paper shares the experience of China Three Gorges Corporation in intelligent grouting management for dam foundation reinforcement. An control system called grout hub with (iGHM) was introduced to realize one-button closed-loop cement by its robust models, novel facilities, and online monitoring approaches. In this system, period (<i>t</i>) is intelligently divided into three zones five phases based on product pressure (<i>P</i>) unit rate (<i>Q</i>), which provide quantitative criteria...
Mitochondrial retrograde regulation (MRR) is the transduction of mitochondrial signals to mediate nuclear gene expression. It not clear whether MRR a common mechanism in plant abiotic stress response. In this study, we analysed early response rice OsAOX1 genes, and induction OsAOX1a OsAOX1b (OsAOX1a/b) was selected as working model for stress-induced studies. We found that mediated by superoxide ion (O2·(-) )-generating chemical methyl viologen stronger than hydrogen peroxide (H2 O2 ). The...
Reactive oxygen species (ROS) are harmful to all living organisms and therefore they must be removed ensure normal growth development. ROS also signaling molecules, but so far little is known about the mechanisms of perception developmental response in plants. We here report that hydrogen peroxide induces cortex proliferation Arabidopsis root SPINDLY (SPY), an O-linked glucosamine acetyltransferase, regulates by maintaining cellular redox homeostasis. found mutation leucine-rich receptor...
The newly emerging variants of SARS-CoV-2 from India (Delta variant) and South America (Lambda have led to a higher infection rate either vaccinated or unvaccinated people. We found that sera Pfizer-BioNTech vaccine remain high reactivity toward the receptor binding domain (RBD) Delta variant while it drops dramatically Lambda variant. Interestingly, overall titer antibodies individuals 3-fold after 6 months, which could be one major reasons for breakthrough infections, emphasizing...
Abstract Severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) is causing a world-wide pandemic. A variant of SARS-COV-2 (20I/501Y.V1) recently discovered in the United Kingdom has single mutation from N501 to Y501 within receptor binding domain (Y501-RBD), Spike protein virus. This much more contagious than original version (N501-RBD). We found that this mutated RBD binds human Angiotensin Converting Enzyme (ACE2) ~10 times tightly native Modeling analysis showed N501Y would...
Abstract We generated several versions of the receptor binding domain (RBD) Spike protein with mutations existing within newly emerging variants from South Africa and Brazil. found that mutant RBD K417N, E484K, N501Y exchanges has higher affinity to human compared wildtype RBD. This mutated version also completely abolishes a therapeutic antibody, Bamlanivimab, in vitro .
Colistin is considered a last-resort antibiotic against most gram-negative bacteria. Recent discoveries of plasmid-mediated, transferable mobilized colistin-resistance gene (mcr-1) on all continents have heralded the imminent emergence pan–drug-resistant superbacteria. The inner-membrane protein MCR-1 can catalyze transfer phosphoethanolamine (PEA) to lipid A, resulting in colistin resistance. However, little known about mechanism, and few drugs exist address this issue. We present crystal...
A chemical-vapor deposition-like strategy was developed for the synthesis of versatile core–shell transition metal sulfide (TMS)@carbon heterostructured nanowires electrochemical sodium ion storage.
The influence of rock mechanical properties on the electromagnetic radiation (EMR) mechanism fracturing is an important research topic in solid mechanics and earthquake prediction. In this study, EMR model considering fracture factor, elastic modulus, Poisson's ratio, distance crack length derived based Hertz oscillator array assumption. An experimental system, including shielding module, signal induction transmission a recording module loading developed to understand characteristics four...