A5072863630- Natural Antidiabetic Agents Studies
- Phytochemistry and Biological Activities
- Botanical Research and Chemistry
- Ziziphus Jujuba Studies and Applications
- Seed and Plant Biochemistry
- Drug Transport and Resistance Mechanisms
- Ethnobotanical and Medicinal Plants Studies
- Pregnancy and Medication Impact
- Plant Toxicity and Pharmacological Properties
- Phytochemistry and Bioactive Compounds
- Toxin Mechanisms and Immunotoxins
- Psidium guajava Extracts and Applications
Centre National de la Recherche Scientifique et Technologique
2022-2025
Institut de Recherche en Sciences de la Santé
2022-2025
Balanites aegyptiaca (L.) Delile (Zygophyllaceae) is a medicinal plant used in traditional medicine Burkina Faso to treat helminthiasis. Using an ethnopharmacological approach, the "Institut de Recherche en Sciences la Santé (IRSS)" has developed phytomedicine based on almond extract from fruit of this for treatment This study aimed assess acute and subacute oral toxicity vivo mutagenicity phytomedicine. The was carried out following OECD guideline 423 by administering single dose 2000 mg/kg...
In Burkina Faso, sickle cell syndromes affect 8.42% of hospital patients. For the management anemia, a phytomedicine called FACA® capsules based on mixture roots barks powdered from Calotropis procera and Zanthozylum zanthozyloïdes has been developed. The objective this study was to evaluate acute sub-chronic toxicity mixture. Toxicity studies were conducted according OECD guidelines Wistar rats. test estimated LD50 be 5000 mg/kg body weight. showed significant dose-dependent decrease in...
Sickle cell disease remains a major public health problem in Burkina Faso and Africa. For the management of this pathology young children, Institute for Research Health Sciences has developed an herbal drug called FACA® syrup. The objective study was to verify safety pharmacological efficacy formulation its use sickle disease. Acute subacute oral toxicity tests were performed on Wistar rats accordance with Organization Economic Cooperation Development test guidelines anti-sickling activity...
Anastatica hierochuntica L. (Brassicaceae) has been claimed to treat various conditions including complicated childbirth. The principal objective of this research was provide scientific evidence on the contractile effect aqueous and hydroethanolic extracts whole plant from A. during labor. Qualitative quantitative methods helped identify quantify phytoconstituents in both extracts. antioxidant activity studied using four standard methods. inhibitory power pro-inflammatory enzymes such as...
Neptunia oleracea (Lourd.) Mimosaceae is a plant commonly used in traditional medicine for the treatment of several pathologies such as dysentery, jaundice, leucorrhoea, troubles earache, among others.
 Aim: The purpose this study was to carry out preliminary phytochemical screening, acute toxicity studies and evaluate effect aqueous hydro-ethanolic extracts N. on intestinal motility vivo.
 Methodology: Preliminary qualitative screening conducted using standard procedures while...