- Maternal Mental Health During Pregnancy and Postpartum
- Neuroendocrine regulation and behavior
- Pregnancy and Medication Impact
- Menstrual Health and Disorders
- Child and Adolescent Psychosocial and Emotional Development
- Stress Responses and Cortisol
- Maternal and Perinatal Health Interventions
- Bipolar Disorder and Treatment
- Epigenetics and DNA Methylation
- Health Systems, Economic Evaluations, Quality of Life
- Adolescent and Pediatric Healthcare
- Family Support in Illness
- Endometriosis Research and Treatment
- Tryptophan and brain disorders
- Birth, Development, and Health
- Biochemical effects in animals
- Health, Environment, Cognitive Aging
- Neuroscience and Neuropharmacology Research
- Dementia and Cognitive Impairment Research
- Pregnancy and preeclampsia studies
- Global Financial Regulation and Crises
- Reproductive System and Pregnancy
- Attachment and Relationship Dynamics
- Schizophrenia research and treatment
- Sleep and related disorders
Johns Hopkins University
2015-2025
University of Virginia
2021-2025
Johns Hopkins Medicine
2014-2024
Valley Health System
2024
University of Oxford
2009-2021
University of Maryland, Baltimore
2021
Institute of Behavioral Sciences
2020
Johns Hopkins Hospital
1998-2017
American Congress of Obstetricians and Gynecologists
2017
Women’s Health Care
2017
OBJECTIVE: This study was conducted to determine the efficacy and safety of riluzole, a glutamate-modulating agent, in patients with recurrent major depression. METHOD: After 1-week drug-free period, subjects 18 years or older diagnosis depression Montgomery-Åsberg Depression Rating Scale score ≥20 received riluzole monotherapy (100–200 mg/day) openly for 6 weeks. RESULTS: Nineteen treatment-resistant depressed patients, 53% whom were classified as having stage 2 treatment resistance...
Considerable research suggests that suicide involves effects of genes, the environment, and their interaction. Analysis three independent data sets post-mortem brains revealed signs increased methylation in one particular gene, SKA2, a finding was extended to peripheral blood samples from other cohorts prospectively followed individuals.
Premenstrual symptoms, including physical and mood affect a large proportion of women worldwide. Data on premenstrual symptoms across nations age groups is limited. In the present study, we leveraged international dataset to explore patterns in symptom frequency with age. A survey was administered users Flo mobile application (app), aged 18 55. The queried app about range symptoms. Respondents were asked whether they experienced each every menstrual cycle, some cycles, or never. Age also...
Objective: Family studies have suggested that postpartum mood symptoms might a partly genetic etiology. The authors used genome-wide linkage analysis to search for chromosomal regions harbor variants conferring susceptibility such symptoms. then fine-mapped their best regions, assessing single nucleotide polymorphisms (SNPs) association with Method: Subjects were ascertained from two studies: the NIMH Genetics Initiative Bipolar Disorder project and of Recurrent Early-Onset Depression....
Suicide is the second leading cause of death among adolescents in USA, and rates are rising. Methods to identify individuals at risk essential for implementing prevention strategies, development a biomarker can potentially improve prediction suicidal behaviors. Prediction our previously reported SKA2 suicide PTSD substantially improved by questionnaires assessing perceived stress or anxiety therefore reliant on psychological assessment. However, such stress-related states may also leave...
To evaluate the association between maternal age, parity, gestational number (singleton vs twin), newborn gender and self-reported postpartum depressive symptoms (PDS) in a large multinational sample using survey data from digital telephone application.