To estimate the rates and patterns of major depression bipolar disorder based on cross-national epidemiologic surveys.Population-based studies using similar methods from 10 countries: United States, Canada, Puerto Rico, France, West Germany, Italy, Lebanon, Taiwan, Korea, New Zealand.Approximately 38000 community subjects.Rates, demographics, age at onset disorder. Symptom profiles, comorbidity, marital status with depression.The lifetime for vary widely across countries, ranging 1.5 cases...

Data from five psychiatric populations and a community sample are presented on the CES-D, 20-item self-report depression symptom scale developed by Center for Epidemiologic Studies. Results show that is sensitive tool detecting depressive symptoms change in over time populations, it agrees quite well with more lengthy scales used clinical studies clinician interview ratings. Although cannot differentiate between diagnositc groups, CES-D has demonstrated its validity as screening populations.

Current emphasis on early case finding, outpatient care, and longitudinal studies of asymptomatic patients has focused attention the community adjustment psychiatric patients. Thus, simple inexpensive methods such as self-report scales, which allow routine assessment patient adjustment, are potentially useful. The derivation testing a method, Social Adjustment Scale Self-Report, is described. This scale covers patient's role performance, interpersonal relationships, friction, feelings...

• Six-month prevalence rates for selected DSM-III psychiatric disorders are reported based on community surveys in New Haven, Conn, Baltimore, and St Louis. As part of the Epidemiologic Catchment Area program, data were gathered more than 9,000 adults, employing Diagnostic Interview Schedule to collect information make a diagnosis. The most common found phobias, alcohol abuse and/or dependence, dysthymia, major depression. diagnoses women phobias depression, whereas men, predominant disorder...

Objective: This study was a 20-year follow-up of offspring depressed and nondepressed parents to determine the magnitude continuity risk parental depression offspring. Method: The authors followed 151 moderately severely or nonpsychiatrically ill comparison subjects for about 20 years, mean age 35 years. Four interviews diagnostic assessments from childhood adolescence adulthood were conducted by assessors blind parents’ clinical status offspring’s previous history. Final best-estimate...

ContextMajor depressive disorder (MDD) that arises in adolescence impairs functioning and is associated with suicide risk, but little known about its continuity into adulthood.ObjectiveTo describe the clinical course of adolescent-onset MDD adulthood.Design ParticipantsProspective case-control study. Seventy-three subjects had onset based on systematic assessment during (Tanner stage III-V) 37 controls no evidence past or current psychiatric disorders, also were assessed (assessment years:...

This paper reports on the testing of self-report scales, in a pilot study 28 children with psychiatrically ill parent. We examined relationship between children's responses about themselves and mothers' their children, symptom social functioning scales. The scales administered to included Center for Epidemiologic Studies Depression Scale, Children's Inventory, Social Adjustment Scale. mothers completed Achenbach Child Behavior Checklist, Conners Parent Questionnaire, Scale children....

The authors gave the CES-D, a self-report depression symptom scale, to 515 people drawn from longitudinal community survey. subjects were also interviewed using Schedule for Affective Disorders and Schizophrenia (SADS). From information collected on SADS, given diagnoses based Research Diagnostic Criteria. results indicate modest relationship between self-reported symptoms of diagnosis major or minor depression. However, groups defined as "cases" by such reports include many with other no at...

Article Abstract Background: Our goal was to estimate the rate of positive screens for bipolar I and II disorders in general population United States. Method: The Mood Disorder Questionnaire (MDQ), a validated screening instrument disorders, sent sample 127,800 people selected represent U.S. adult by demographic variables. 85,358 subjects (66.8% response rate) that were 18 years age or above returned survey had usable data. Of nonrespondents, 3404 matched demographically 2000 Census data...

• The current point and lifetime prevalence rates of affective disorders, based on the application Research Diagnostic Criteria to a US urban community sample, are reported. disorders studied included major minor depression, mania, hypomania, bipolar I II, primary secondary schizo-affective disorder, depressive cyclothymic personality, grief reactions. Epidemiologic surveys that include treated untreated persons obtain specific psychiatric needed for scientific purposes health care planning.

Results on the age/sex specific prevalence of DSM-III affective disorders from NIMH Epidemiologic Catchment Area Study (ECA), a probability sample over 18,000 adults five United States communities, are presented. The cross-site means for bipolar disorder ranged 0.7/100 (2 weeks) to 1.2/100 (lifetime), with mean age onset 21 years and no sex difference in rates. major depression 1.5/100 4.4/100 27 higher rates women. dysthymia, chronic condition, was 3.1/100 rate There reasonable consistency...

<h3>Background:</h3> There have been numerous studies that shown offspring of depressed parents are at a high risk for major depressive disorder (MDD) and impairment. None followed up the into adulthood to obtain more precise estimates risk. <h3>Method:</h3> One hundred eighty-two from 91 families, in which 1 or had MDD (high risk) neither parent was (low risk), were blindly reassessed third follow-up, using structured diagnostic instrument 10 years after their initial identification....

ContextChildren of depressed parents have high rates anxiety, disruptive, and depressive disorders that begin early, often continue into adulthood, are impairing.ObjectiveTo determine whether effective treatment with medication women major depression is associated reduction symptoms diagnoses in their children.DesignAssessments children whose mothers were being treated as part the multicenter Sequenced Treatment Alternatives to Relieve Depression (STAR*D) trial conducted (between December...

Panic disorder, which is found in about 1.5 percent of the population at some time their lives, includes recurrent episodes sudden, unpredictable, intense fear accompanied by symptoms such as palpitations, chest pain, and faintness. attacks, do not meet these diagnostic criteria fully, are two to three times more prevalent. Since panic can mimic those other medical disorders, patients with use services frequently. To determine risk suicidal ideation suicide attempts disorder we studied a...

Despite the importance of mental illness in Africa, few controlled intervention trials related to this problem have been published.To test efficacy group interpersonal psychotherapy alleviating depression and dysfunction evaluate feasibility conducting Africa.For cluster randomized, clinical trial (February-June 2002), 30 villages Masaka Rakai districts rural Uganda were selected using a random procedure; 15 then randomly assigned for studying men women. In each village, adult or women...

Understanding the consequences of regulatory variation in human genome remains a major challenge, with important implications for understanding gene regulation and interpreting many disease-risk variants that fall outside protein-coding regions. Here, we provide direct window into genetic by sequencing RNA from 922 genotyped individuals. We present comprehensive description distribution variation--by specific expression phenotypes altered, properties affected genes, genomic characteristics...

Background. There are few cross-national comparisons of the rates suicide ideation and attempts across diverse countries. Nine independently conducted epidemiological surveys using similar diagnostic assessment criteria provided an opportunity to obtain that data. Methods. Suicide were assessed on Diagnostic Interview Schedule in over 40000 subjects drawn from United States, Canada, Puerto Rico, France, West Germany, Lebanon, Taiwan, Korea New Zealand. Results. The lifetime prevalence...

Brief screens to collect lifetime family psychiatric history are useful in clinical practice and for identifying potential families genetic studies.The Family History Screen (FHS) collects information on 15 disorders suicidal behavior informants their first-degree relatives. Since each question is posed only once about all members as a group, the administrative time 5 20 minutes, depending size illness. Data validity against best-estimate (BE) diagnosis based independent blind direct...

• Data on the psychiatric diagnosis, overall functioning, and treatment of 220 6- to 23-year-old subjects who were at high or low risk for major depression are presented. The subjects' diagnoses made by a child psychiatrist based bestestimate evaluation diagnostic information derived from structured interviews (Schedule Affective Disorders Schizophrenia School-Aged Children, Epidemiologic Version) with separately their mothers about children. findings an increased prevalence substance abuse,...

Psychotherapy is widely used for depressed adolescents, but evidence supporting its efficacy sparse.In a controlled, 12-week, clinical trial of Interpersonal Depressed Adolescents (IPT-A), 48 clinic-referred adolescents (aged 12-18 years) who met the criteria DSM-III-R major depressive disorder were randomly assigned to either weekly IPT-A or monitoring. Patients seen biweekly by "blind" independent evaluator assess their symptoms, social functioning, and problem-solving skills. Thirty-two...

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