A5101406988- Acute Myeloid Leukemia Research
- Acute Lymphoblastic Leukemia research
- Genetic diversity and population structure
- RNA Interference and Gene Delivery
- Plant Pathogens and Fungal Diseases
- Plant Taxonomy and Phylogenetics
- Turfgrass Adaptation and Management
- Rangeland and Wildlife Management
- Lymphoma Diagnosis and Treatment
- Virus-based gene therapy research
- Chronic Myeloid Leukemia Treatments
- Chromosomal and Genetic Variations
- Retinoids in leukemia and cellular processes
- Childhood Cancer Survivors' Quality of Life
- Advanced biosensing and bioanalysis techniques
- Cancer-related molecular mechanisms research
- Livestock Management and Performance Improvement
- CAR-T cell therapy research
- RNA modifications and cancer
- Plant Disease Resistance and Genetics
- Ultrasound and Hyperthermia Applications
- Wheat and Barley Genetics and Pathology
- Neutropenia and Cancer Infections
- Plant Virus Research Studies
- Genetics and Plant Breeding
Guizhou Provincial People's Hospital
2025
Lanzhou University
2025
State Key Laboratory of Herbage Improvement and Grassland Agro-ecosystems
2025
Qingdao University of Science and Technology
2025
Henan Agricultural University
2013-2024
Chongqing Medical University
2011-2024
Children's Hospital of Chongqing Medical University
2011-2024
China International Science and Technology Cooperation
2016-2024
Guangdong Pharmaceutical University
2024
Nankai University
2022
Abstract Background Geographical variation in morphological traits may reflect evolutionary patterns of adaptability along environmental gradients. Comprehensive information on longitudinal trait is very meaningful to explore diversity and trends widespread bermudagrass. Methods To the spatial traits, we investigated 10 bermudagrass soil nutrient indexes collected local climate data for 13 different regions from 119°E 105°E latitude 34°N. Results Considerable variations were observed at...
Infection with Ascochyta medicaginicola triggers the production of defensive secondary metabolites in plants, varying levels observed across two alfalfa varieties. Among six identified, 3-indoleacrylic acid (YD) and 3-ethynylaniline (EL) exhibited antifungal activity, achieving inhibition rates 82.21 66.36% at 200 μg/mL, respectively. YD EL exerted protective therapeutic effects, reducing leaf lesion areas by more than 96.00% compared to blank control. The mechanisms against A. included...
In this work, a one‐step method synthesis of lactide was reported instead the traditional two‐step method. The selection suitable acid catalyst polyphosphoric (PPA) and optimization reaction conditions resulted in yield 97%. Moreover, new strategy eliminates need for metal catalysts does not require high‐temperature conditions, thereby avoiding issue racemization. simple offers combination efficiency, sustainability, product quality improvements, making it modern, practical approach to synthesis.
Fall dormancy (FD) is an important indicator of winter hardiness in alfalfa ( Medicago sativa L.), but the relationship between FD and yield potential varieties with contrasting classes has not been determined temperate regions mild winters. This study was conducted 42 eight (2–9) over four consecutive years to determine seasonal annual total dry matter (DM) yields classes. The results showed that all survived without any persistency problems during production years. greatest average DM 24.4...
Understanding the population genetic pattern and process of gene flow requires a detailed knowledge how landscape characteristics structure populations. Although Cynodon dactylon (L.) Pers. (common bermudagrass) is widely distributed in world, information on its along latitudinal gradients limited. We tried to estimate diversity C. gradient across China. Genetic among different ploidy levels was also compared study. The material used consisted 296 individuals sampled from 16 geographic sites...
Abstract Knowledge of ploidy level and genome size in a germplasm collection is critical before studying genetic diversification different environmental range grasses other plants. We assessed the geographic patterns 216 individuals Cynodon dactylon (L.) Pers. (common bermudagrass) by flow cytometry accessions sampled from 16 sites along latitudinal gradient 22°35′ N to 36°18′ across China. Flow histograms combined with mitotic chromosome observations results show that tetraploids were most...
This complex environmental heterogeneity coupled with the long-standing history offers scenario suitable for and favoring evolution existence of variation morphological traits. In this study, we measured 10 traits 310 Cynodon dactylon individuals sampled at 16 different locations along latitudinal gradients between 22°35′N 36°18′N to reveal phenotypic plasticity influenced by latitude. addition, relationships soil nutrient climate factors were analyzed. Analysis variance, divesity...
Abstract Background The KMT2A gene, formerly named the MLL is rearranged ( r) in 70–75% of infants, 5–6% children and 10–15% adult patients with B cell acute lymphoblastic leukemia (B-ALL). outcome after chemotherapy pediatric cases remains poor, only a few studies have investigated clinical laboratory features, treatment response prognosis Chinese populations. Methods A total 48 B-ALL r were enrolled study, data collected analyzed by age group. relationship between traditional risk factors...
Abstract Background The novel gene HA117 is a multidrug resistance (MDR) expressed by all-trans retinoic acid-resistant HL-60 cells. In the present study, we compared of with that classical 1 (MDR1) in breast cancer cell line 4T1. Methods Transduction 4T1 adenoviral vectors encoding and green fluorescence protein (GFP) (Ad-GFP-HA117), MDR1 GFP (Ad-GFP-MDR1) or (Ad-GFP) was respectively carried out. transduction efficiency multiplicity infection (MOI) were detected microscope flow cytometry....
HomePlant DiseaseVol. 104, No. 3First Report of Alfalfa Leaf Curl Virus Infecting (Medicago sativa) in China Previous DISEASE NOTES OPENOpen Access licenseFirst ChinaZ. P. Guo, J. X. Zhang, M. L. Wang, Y. Z. Guan, G. Qu, Liu, and B. YanZ. Guohttp://orcid.org/0000-0002-6550-3448College Animal & Veterinary Science, Henan Agricultural University, Zhengzhou 450002, China, ZhangCollege WangCollege GuanCollege QuCollege LiuCollege Guo†Corresponding authors: Guo; E-mail Address: yuxiaguo@163.com...
Abstract Introduction To investigate the correlation of long noncoding RNA‐SOX6‐1 (lnc‐SOX6‐1) with clinicopathological features and treatment outcomes in pediatric acute myeloid leukemia (AML) patients, further explore its function AML cell proliferation apoptosis. Methods A total 146 de novo patients 73 nonhematologic malignancy patients/donors were recruited. Bone marrow samples obtained, followed by measurement lnc‐SOX6‐1 expression qPCR. Besides, various cells control was detected....
The aim of this study was to investigate the prevalence and causes low vision blindness in Baotou, Inner Mongolia. A cross-sectional carried out. Multistage sampling used select samples. visual acuity estimated using LogMAR corrected by pinhole as best-corrected acuity. There were 7000 samples selected 5770 subjects included investigation. overall bilateral rates 3.66% (95% CI: 3.17–4.14) 0.99% 0.73–1.24), respectively. vision, blindness, impairment increased with age decreased education...
Clostridial fermentation is the determining process causing spoilage of direct-cut alfalfa silage, and application lactic acid bacteria (LAB) inoculant considered as most promising technology for inhibiting clostridial fermentation. In order to screen target-based LAB strains, identification correlation analysis key Clostridia species in silage were conducted this study. Three cultivars (Sanditi, SD; Celsius, CE; SW5909, SW) harvested at early bloom stage ensiled without (CK) or with (LB)...
Palladium-NHCs served as highly efficient precatalysts for SMPs of dichloroarenes with diarylboronic acids, affording high molecular weight CPs yields.
Abstract Objective A novel multi-drug resistance gene named as HA117 has been screened and cloned in multidrug resisitant leukemia cell lines our previous research, but its function is still unknown. In this study, was investigated whether it could increase the drug chronic myelogenous myeloid line K562. Methods adenovirus vectors were constructed with (Adeasy-HA117). K562 cells infected by Ad-HA117 to get K562/Ad-HA117 expression. The infection efficiency multiplicity of (MOI) detected...
All-trans retinoic acid (ATRA) induces complete remission in almost all patients with acute promyelocytic leukemia (APL) via its ability to induce the vivo differentiation of APL blasts. However, prolonged ATRA treatment can result drug resistance. In previous studies, we generated a multi-drug-resistant HL60/ATRA cell line and found it contain new resistance-related gene segment, HA117. this study, demonstrate that subpopulations HL60 cells putative stem-like signature by up-regulating...
Elymus sibiricus L. is a perennial allotetraploid belonging to Triticeae of Poaceae, L., as the type species genus The existing geographical distribution pattern and genetic spatial structure E. on Qinghai–Tibetan Plateau (QTP) are not yet clear. In this study, population demography history 216 individuals from 44 populations QTP were studied used specific-locus amplified fragment sequencing (SLAF-seq). result diversity showed that there was no single center observed across all populations....
Abstract Genetic diversity was investigated for forty populations of ten Elymus species from the Tibetan and Inner Mongolian plateaus China using allozyme micro‐satellite markers. The two assays differed in amount polymorphism detected. Micro‐satellites detected higher amounts polymorphism. For allozymes markers, between each species, proportion polymorphic loci, heterozygosity Shannon's Information index ranged 0·1667 to 0·833, 0·455 1·00, respectively, 0·0800 0·2528 0·1622 0·3619, 0·1173...
Cynodon dactylon (L.) Pers. (common Bermuda grass) has a limited capacity to grow at low temperatures, which limits its geographical range. Exploring evolutionary relationship across different environmental gradients is necessary understand the effects of temperature change on genetics common grass. In this study, high-throughput transcriptome sequencing was performed 137 samples C. from 16 latitudinal explore differential molecular markers and analyze genetic diversity structure along...