Wenlong Gou

ORCID: 0000-0001-7432-3011
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About
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Research Areas
  • Ruminant Nutrition and Digestive Physiology
  • Soil Carbon and Nitrogen Dynamics
  • Orthopaedic implants and arthroplasty
  • Bone and Joint Diseases
  • Hip disorders and treatments
  • Bone health and treatments
  • Food Industry and Aquatic Biology
  • Genetic diversity and population structure
  • Total Knee Arthroplasty Outcomes
  • Turfgrass Adaptation and Management
  • Plant Taxonomy and Phylogenetics
  • Phytase and its Applications
  • Hip and Femur Fractures
  • Muscle metabolism and nutrition
  • Genetic and phenotypic traits in livestock
  • Agroforestry and silvopastoral systems
  • Plant and Fungal Species Descriptions
  • Bioenergy crop production and management
  • Bone health and osteoporosis research
  • Orthopedic Infections and Treatments
  • Forest, Soil, and Plant Ecology in China
  • Surgical site infection prevention
  • Plant Molecular Biology Research
  • Periodontal Regeneration and Treatments
  • Mesenchymal stem cell research

Southwest University of Science and Technology
2023-2025

Sichuan Academy Of Social Sciences
2018-2025

Chinese PLA General Hospital
2012-2023

Army Medical University
2017-2023

Daping Hospital
2016-2023

Peking University
2023

Peking University Third Hospital
2023

People's Liberation Army No. 150 Hospital
2013

Chinese People's Liberation Army
2013

The 309th Hospital of Chinese People's Liberation Army
2013

Dysregulated microRNAs (miRNAs) play an important role in osteosarcoma (OS) progression. In the present study, we investigate clinical significance of serum miR-491 level and potential OS lung metastasis chemoresistance. Clinical data show that was decreased from patients compared with healthy control subjects, a is correlated increased metastasis, poor chemoresponse, lower survival rate patients. vitro vivo experiments overexpression suppresses cell whereas it enhances cisplatin...

10.1016/j.ymthe.2017.05.018 article EN cc-by-nc-nd Molecular Therapy 2017-06-23

Objective To detect and compare the bone microstructure osteoblast osteoclast activity in different regions of human osteonecrotic femoral heads. Methods Osteonecrotic heads were obtained from 10 patients (6 males, 4 females; Ficat IV) undergoing total hip arthroplasty between 2011 2013. The samples divided into subchondral bone, necrotic, sclerotic, healthy based on micro-computed tomography (CT) images. microstructure, micromechanics, assessed using micro-CT, pathology,...

10.1371/journal.pone.0096361 article EN cc-by PLoS ONE 2014-05-06

Bone marrow is an important source of stem cells, which can promote bone fracture healing. We investigated the optimal time to inject mesenchymal cells (BMSCs) in a C57 murine unilateral, transverse, femur model. BMSCs transfected with red fluorescent protein (RFP-BMSCs) were injected via tail vein on day 1, 7, or 14 post-fracture. AMD3100 (inhibitor stromal cell-derived factor 1 [SDF-1]) was also before RFP-BMSCs one group for comparison; control received saline injections. RFP-BMSC...

10.1186/s13287-018-1034-7 article EN cc-by Stem Cell Research & Therapy 2018-10-25

To investigate the effects of lactic acid bacteria inoculant (LI) and abandoned rhubarb stalk (RS) on anaerobic fermentation bacterial community alfalfa Qinghai Tibetan Plateau, was harvested ensiled without (control) or with LI RS at ambient temperature (5 ∼ 15℃) for 90 days. Addition ensiling increased (P < 0.05) lactate, acetate propionate contents, decreased final pH value as compared control. alpha diversity indices, while inherent Lactococcus lactis and/or Lactobacillus sakei dominated...

10.1016/j.biortech.2021.126347 article EN cc-by-nc-nd Bioresource Technology 2021-11-19

Galega orientalis, a leguminous herb in the Fabaceae family, is an ecologically and economically important species widely cultivated for its strong stress resistance high protein content. However, genomic information of orientalis has not been reported, which limiting evolutionary analysis. The small genome size makes chloroplast relatively easy to obtain sequence phylogenetic studies molecular marker development. Here, was sequenced annotated. results showed that G. 125,280 bp length with...

10.3390/genes14010176 article EN Genes 2023-01-09

Elymus nutans Griseb. (Poaceae: Triticeae, 2n=6x=42) is a dominant perennial plant species in the Qinghai-Tibetan Plateau China, which an important forage resource high-altitude and cold regions most popular used for high yield artificial grassland planting because of its rich nutritional value good palatability herbivorous ruminant animals. In this study, using advanced sequencing technology, we generated allohexaploid reference genome E. nutans, representing three sets chromosomes...

10.1101/2025.03.29.645954 preprint EN cc-by-nc-nd 2025-03-31

This study aimed to investigate the effects of delayed harvest and additives on fermentation quality bacterial community corn stalk silage in South China. The stalks after ear at 0 day (D0), 7 days (D7), 15 (D15) were used produce small-bale silages. silages each time treated without (control, CK) or with Lactobacillus plantarum (LP) sodium benzoate (BF). results showed that increased pH acetic acid content reduced lactic ( p &amp;lt; 0.05). Compared CK, decreased contents butyric ammonia...

10.3389/fmicb.2021.687481 article EN cc-by Frontiers in Microbiology 2021-07-07

Intertrochanteric fracture is a very common but serious type of hip in nonagenarians. The surgical treatment remains significant challenge for orthopedists. objective this study was to investigate postoperative complications and survival outcomes compared between bipolar hemiarthroplasty (HA) proximal femoral nail anti-rotation (PFNA) nonagenarians with intertrochanteric fractures, evaluate the efficacy safety two procedures patient population.A total 113 consecutive who underwent HA or PFNA...

10.1111/os.13913 article EN cc-by-nc-nd Orthopaedic Surgery 2023-10-25

Bisphosphonates (BPs) have been widely used in clinical treatment of bone diseases with increased resorption because their strong affinity for and inhibition resorption. Recently, there has growing interest improvement formation. However, the effect local controlled delivery BPs is unclear. We polylactide acid-glycolic acid copolymer (PLGA) as a drug carrier to deliver various doses bisphosphonate zoledronate (Zol) into distal femur 8-week-old Sprague-Dawley rats. After 6 weeks, samples were...

10.1371/journal.pone.0091317 article EN cc-by PLoS ONE 2014-03-11

To effectively use local available grass resources to cover the winter feed shortage on Qinghai-Tibetan Plateau, direct-cut and wilted reed canary (RCG) silages were prepared by using a rolled-bale system, their ensiling characteristics in vitro digestibility studied. Silages treated without (control) or with inoculants including LP (Lactobacillus plantarum), LPLB (L. plantarum, L. buchneri), LPLBc buchneri, cellulase), stored at ambient temperature (5.7-14.6°C) for 90 days. Compared...

10.1111/asj.13364 article EN Animal Science Journal 2020-01-01

Prairie grass (Bromus catharticus Vahl) is an important species that could be used in the production systems of certified seed and high-quality forage for grazing ruminants. In present research, a sequence-related amplified polymorphism (SRAP) marker was employed to detect genetic variability structure 80 prairie accessions from all over world. Altogether, 460 reliable bands were 47 SRAP primer pairs with 345 (75%) polymorphic bands. The average values discrimination power (DP) information...

10.3390/agronomy11102054 article EN cc-by Agronomy 2021-10-13

Abstract Background This study aimed to investigate the effect of phenyllactic acid as an additive on silage fermentation and bacterial community reed canary grass (RCG, Phalaris arundinacea L.) Qinghai Tibetan Plateau. At heading stage, RCG was harvested, chopped ensiled in small bag silos. The treated without (control, 1.0 g/mL sterile water, a fresh matter basis (FM)) or with (PLA, 3 mg/mL, FM), antimicrobial (PSB, mixture potassium sorbate sodium benzoate, 2%, lactic bacteria inoculant...

10.1186/s12866-022-02499-w article EN cc-by BMC Microbiology 2022-03-30

To effectively use local grass resources to cover the winter feed shortage on Qinghai-Tibetan Plateau, silage fermentation and in vitro digestibility of perennial oat (

10.3390/microorganisms9112403 article EN cc-by Microorganisms 2021-11-22
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