A5004448267- Nanoparticle-Based Drug Delivery
- Electrospun Nanofibers in Biomedical Applications
- Advanced Drug Delivery Systems
- Bone Tissue Engineering Materials
- Advanced biosensing and bioanalysis techniques
- Graphene and Nanomaterials Applications
- Helicobacter pylori-related gastroenterology studies
- Bacteriophages and microbial interactions
- Pharmacological Effects of Natural Compounds
- Nanoplatforms for cancer theranostics
- Nanoparticles: synthesis and applications
- RNA Interference and Gene Delivery
- Dental materials and restorations
- Essential Oils and Antimicrobial Activity
- 3D Printing in Biomedical Research
- Dendrimers and Hyperbranched Polymers
- Tissue Engineering and Regenerative Medicine
- Oral microbiology and periodontitis research
- Zebrafish Biomedical Research Applications
- Collagen: Extraction and Characterization
- Phytochemicals and Medicinal Plants
- Gold and Silver Nanoparticles Synthesis and Applications
- Antifungal resistance and susceptibility
- Endodontics and Root Canal Treatments
- Monoclonal and Polyclonal Antibodies Research
Chettinad Academy of Research and Education
2016-2025
University of Oklahoma
2010-2023
Martin Luther University Halle-Wittenberg
2019
Chettinad Health City
2016
Indian Institute of Technology Madras
2013-2016
University of California, Los Angeles
2010
Texas Biomedical Research Institute
2010
University of Madras
2004-2009
Mattel Children's Hospital
2008
Ronald Reagan UCLA Medical Center
2008
Angiotensin-converting enzymes, ACE and ACE2, play not only a pivotal role in the regulation of blood pressure, but are involved processes pathophysiology, including thyroid dysfunction or progression several neoplasia such as cancers skin, lungs, pancreas leukemia. However, their carcinogenesis remains unknown. We examined this study expression ACE2 tissues possible employment biomarkers for cancer progression. Thyroid tissues, 14 goiters (G), 12 follicular adenomas (FA), 10 carcinomas...
Abstract Filamentous M13 phage can be engineered to display cancer cell–targeting or tumor-homing peptides through display. It would highly desirable if the tumor-targeting also carry anticancer drugs deliver them cells. We studied evolution of structures complexes between anionic filamentous and cationic serum-stable liposomes that encapsulate monomeric photosensitizer zinc naphthalocyanine. At specific phage-liposome ratios, multiple nanofibers are interwoven into a “nanoweb.” The chemical...
Abstract Lysosomal instability has been suggested as a major factor in the development of cellular injury during myocardial necrosis through formation inflammatory mediators. The present study was designed to investigate effect mangiferin on lysosomal hydrolases and TNF‐ α production isoproterenol (ISPH) induced rats. rats given ISPH (200 mg/kg body weight twice, subcutaneous) for 2 days showed significant increase plasma production, serum heart activity. administration resulted decreased...
This paper presents a detailed and systematic study of amine functionalization silica coating gold nanostructures the electrostatic covalent binding prepared capped to BSA. The involvement Tryptophan residue in hydrophobic pocket BSA its interaction with was established. Fluorescence studies tryptophan residues protein molecules after conjugation revealed that method crosslinking did not bring about major changes constant (1012 M−1) nanostructures. Electrostatic indicated larger number sites...
Narayan S, Tsai EW, Zhang Q, Wallace WD, Reed EF, Ettenger RB. Acute rejection associated with donor‐specific anti‐MICA antibody in a highly sensitized pediatric renal transplant recipient. Pediatr Transplantation 2011: 15:E1–E7. © 2010 John Wiley & Sons A/S. Abstract: Allograft HLA identical recipients and patients without detectable anti‐HLA antibodies has lead to the identification of non‐HLA antigens as targets alloimmune response. MICA antigen been recognized an important target...
The ethanol extract of Pterocarpus santalinus (PS) was evaluated for gastroprotection in rats using ibuprofen as the induction model. Rats treated with PS (100–400 mg/kg) showed a significant reduction gastric lesions. at dose 200 mg/kg found to be minimum effective and hence further studies that were carried out. treatment increased LDH activity decreased lipid peroxidation levels. had ability increase antioxidant enzymes SOD, CAT GPx when compared untreated but induced rats. membrane bound...
The methanol extract of the bark Terminalia arjuna (Combretaceae) (TAE) showed marked antiulcer and ulcer healing activity against 80% ethanol (ETH), diclofenac sodium (DIC) dexamethasone (DEX) induced models dose dependently at doses 100, 400 200 mg/kg body weight respectively. Pre-, post co-administration TAE offered 100% protection to gastric mucosa ETH, DIC DEX ulcers as observed from score. Gastric mucosal analysis rats were associated with changes in levels protein, protein bound...
Objectives This review explores the vital role of oligodendrocytes in axon myelination and efficient neuronal transmission impact dysfunction resulting from neurotransmitter deficiencies related disorders. Furthermore, also provides insight into potential bionanotechnology for addressing neurodegenerative diseases by targeting oligodendrocytes.
Abstract: Environmental factors like UV radiation and epigenetic changes are significant for skin cancer that trigger early aging. This review provides essential information on development concerning aging, the receptors involved, therapeutic targets. Biopolymers polysaccharide, polyphenols, proteins, nucleic acid plays a vital role in regulation of normal cell homeostasis. Therefore, it is pertinent to explore biopolymers as antiaging formulations possibility these being used against via...