A5083721221- Gastrointestinal Bleeding Diagnosis and Treatment
- Gastrointestinal disorders and treatments
- Pediatric Hepatobiliary Diseases and Treatments
- Trace Elements in Health
- Gastrointestinal Tumor Research and Treatment
- Cholesterol and Lipid Metabolism
- Iron Metabolism and Disorders
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Heavy Metal Exposure and Toxicity
- Cell Adhesion Molecules Research
- Congenital Diaphragmatic Hernia Studies
- Neuroendocrine Tumor Research Advances
- Platelet Disorders and Treatments
Istituto Giannina Gaslini
2020-2024
University of Genoa
2020-2024
Istituti di Ricovero e Cura a Carattere Scientifico
2020-2023
The endoscopic findings were suggestive of duodenum Dieulafoy's lesion (DL). We performed successful haemostasis by administering epinephrine injections and subsequent thermal coagulation with argon plasma. Repeat endoscopy 5 days later exhibited no signs complications or rebleed. infant was able to continue chemotherapy without recurrence symptoms. DL the is an extremely rare but potentially life-threatening cause gastrointestinal bleeding in infants children.1, 2 consists submucosal,...
Wilson's disease (WD) is a rare autosomal recessive disorder caused by mutations in the ATP7B gene, resulting copper accumulation. Symptoms rarely appear before age of 5, almost never 3. The phenotypic variability WD suggests presence modifying factors, making early diagnosis challenging. We present case symptomatic toddler, emphasizing importance considering differential diagnoses and exploring genetic modifiers influencing onset. Clinical laboratory assessments, including liver biopsy,...
A 15-year-old boy, native of Sudan from consanguineous parents, was evaluated for a 1-year history arthralgias, partially responsive to analgesic therapy, and the presence stretch-elastic consistency skin lesions on extensor surfaces joints. Basal blood tests showed mild normocytic anaemia thrombocytopenia, hypergammaglobulinaemia, hyperferritinaemia increased inflammatory index. Joints bones radiological evaluation normal. The lesion biopsy revealed extensive infiltrate foamy histiocytes...
Treatment of infantile-onset inflammatory bowel disease (IO-IBD) is often challenging due to its aggressive course and failure standard therapies with a need for biologics. Secondary loss response frequently caused by the production anti-drug antibodies, well-known problem in IBD patients on biologic treatment. We present case IO-IBD treated therapeutic drug monitoring (TDM)-guided high-dose anti-tumor necrosis factor therapy, which dose escalation was used as strategy overcome antibodies.A...