A5038849346- Neuroscience and Neural Engineering
- Neurological disorders and treatments
- EEG and Brain-Computer Interfaces
- Electrochemical Analysis and Applications
- Spectroscopy Techniques in Biomedical and Chemical Research
- Analytical Chemistry and Sensors
- Corneal Surgery and Treatments
- Laser-Matter Interactions and Applications
- Muscle activation and electromyography studies
- Parkinson's Disease Mechanisms and Treatments
- Magnetic and Electromagnetic Effects
- Advanced Fiber Laser Technologies
- Plant and Biological Electrophysiology Studies
- Characterization and Applications of Magnetic Nanoparticles
- Transcranial Magnetic Stimulation Studies
- Protein Interaction Studies and Fluorescence Analysis
- Advanced Fluorescence Microscopy Techniques
Linköping University
2010-2019
University of Ottawa
2009
The objective was to develop a physical action potential generator (Paxon) with the ability generate stable, repeatable, programmable, and physiological-like potential. Paxon has an equivalent of 40 nodes Ranvier that were mimicked using resin embedded gold wires (Ø = 20 μm). These software controlled potentials initiated by start trigger. Clinically used Ag-AgCl electrodes coupled for functional testing. Paxon's parameters tunable second order mathematical equation physiologically relevant...
New deep brain stimulation (DBS) electrode designs offer operation in voltage and current mode capability to steer the electric field (EF). The aim of study was compare EF distributions four DBS leads at equivalent amplitudes (3 V 3.4 mA). Finite element method (FEM) simulations (n = 38) around cylindrical contacts (leads 3389, 6148) or contact configurations 6180, SureStim1) were performed using homogeneous patient-specific (heterogeneous) tissue models. Steering effects 6180 SureStim1...
Computational models for activation assessment in deep brain stimulation (DBS) are commonly based on neuronal cable equations. The aim was to systematically compare the distance between a single model implemented MATLAB, and well-established double NEURON. Both have previously been used DBS studies. field distributions generated from point source 3389 lead were applied neuron as input stimuli. Simulations (n = 670) performed with intersecting axon diameters (D) (2.0, 3.0, 5.7, 7.3, 8.7, 10.0...
In situ characterization of the electric field ultrafast pulses is critical in multiphoton microscopy. Although second harmonic generation-based collinear Frequency-Resolved Optical Gating (FROG) addresses this need, interferometric measurement challenged by drift instability, required high sampling density acquired data, and inability to directly use data with conventional FROG retrieval algorithms. We address these issues combining low-pass Fourier filtering active kHz dithering path...