Laser-induced fluorescence (LIF) excitation, UV-UV hole burning, and single vibronic level (SVLF) spectra of jet-cooled o-fluoroanisole (o-FA) were measured. The most intense lowest-frequency band at 36 612 cm(-1) was assigned to the origin stable trans conformer. hole-burning spectrum demonstrated that prominent bands in LIF excitation responsible for metastable non-planar conformer not observed spectra. vibrational assignments performed with aid quantum chemical calculations B3LYP/cc-pVTZ...

Laser-induced fluorescence (LIF), dispersed (DF), mass-resolved one-color resonance enhanced two-photon ionization (RE2PI) and UV-UV hole-burning spectra of 2-aminoindan (2-AI) were measured in a supersonic jet. The demonstrated that the congested vibronic structures observed LIF excitation spectrum responsible for three conformers 2-AI. origins at 36931, 36934, 36955 cm(-1). DF obtained by exciting band showed quite similar vibrational structures, with exception bands around 600-900...

Photoreaction of ketoprofen (KP), one the widely used nonsteroidal anti-inflammatory drugs (NSAIDs), was studied with transient absorption spectroscopy in phosphate buffer solution (pH 7.4) presence basic amino acids histidine (His), lysine (Lys) and arginine (Arg). Deprotonated form KP (KP(-)) excited UV-light irradiation gave rise to carbanion through a decarboxylation reaction. It found that abstracted proton from side chain protonated yield 3-ethylbenzophenone ketyl biradical (EBPH);...

Simultaneous two-photon absorption to one-photon forbidden electronically excited states of diphenylacetylene (DPA) and diphenylbutadiyne (DPB) was investigated by means highly sensitive optical-probing photoacoustic spectroscopy. The incident laser power dependencies on signal intensity indicate that the signals are dominated regime. Two-photon is responsible for transitions gerade based selection rule. bands observed in heat action spectra were assigned with aid quantum chemical...

Reaction of excited ketoprofen (KP) with tryptophan (Trp) and tyrosine (Tyr) in a phosphate buffer solution was studied by the transient absorption spectroscopy. Both amino acids, which would interact KP bovine serum albumin [Monti, S. [2009] Phys. Chem. Phys., 11, 9104-9113], accelerated proton transfer reaction to yield 3-ethylbenzophenone ketyl biradical (EBPH) from carbanion, produced photoexcitation KP(-) through decarboxylation. By means actinometry method benzophenone, quantum...

Photoreaction of 2-(3-benzoylphenyl)propionic acid (ketoprofen, KP) with basic amino acids (histidine, lysine, and arginine) dipeptides (carnosine anserine) including a histidine moiety in phosphate buffer solution (pH 7.4) has been investigated transient absorption spectroscopy. With UV irradiation KP(-) gave rise to carbanion through decarboxylation reaction, the easily abstracted proton from surrounding molecule yield 3-ethylbenzophenone ketyl biradical (EBPH). The as well were found...

2′,3′,5′-Tri-O-acetyl-6,8-dithioguanosine (taDTGuo) is an analogue of nucleosides and currently under investigation as a potential agent for photodynamic therapy (PDT). Excitation by simultaneous two-photon absorption visible or near-infrared light would provide efficient PDT deep-seated tumors. The spectrum taDTGuo was obtained optical-probing photoacoustic spectroscopy (OPPAS). A band corresponding to the S5 ← S0 transition observed at 556 nm, cross-section σ(2) determined be 26 ± 3 GM,...

The UV-UV hole-burning spectra of the jet-cooled 1-aminoindan were measured for first time. Complicated spectral features observed in laser-induced fluorescence excitation spectrum due to two conformers, R and B, firmly separated. On basis measurements B3LYP/cc-pVTZ calculations, low-frequency ring twisting puckering modes assigned. These are coupled S1 state Duschinsky rotation. matrix was calculated from normal predicted by quantum chemical calculations. coupling between conformer B is...

Abstract 6‐Thioguanine (1a) is considered to be photochemotherapeutic due its specific characteristics of photosensitivity UVA light and singlet molecular oxygen generation. To extend phototherapeutic ability, two related thioguanines, 8‐thioguanine (2a) 6,8‐dithioguanine (3a), have been designed explored. Since the solubility these thioguanines in dehydrated organic solvents too poor study, their triacetyl‐protected ribonucleosides, that is, 2′,3′,5′‐tri‐ O ‐acetyl‐6‐thioguanosine (1c),...

2',3',5'-Tri- O-acetyl-6,8-dithioguanosine (taDTGuo) is a nucleoside derivative of drug 6-thioguanine and under further development as potential photochemotherapeutic agent due to its desirable properties photosensitivity UVA light singlet molecular oxygen generation. The photochemical characteristics taDTGuo biological conditions (namely in aqueous solution) were intensively investigated by the steady-state absorption emission, time-resolved near-infrared emission measurements, quantum...

Relaxation of excited states and reactivity ketoprofen (KP), one the most popular nonsteroidal anti-inflammatory drugs, with indole methylindoles have been studied transient absorption quantum chemical calculations. KP in triplet state, 3KP*, abstracted a hydrogen atom from to afford ketyl radical counter radical. The bimolecular quenching rate constants 3KP* by methylindoles, kq, abstraction constants, kr, were obtained. kr values for larger than that indole; addition, spectra at around 350...

Two-photon absorption for diphenylacetylene (DPA) derivatives with two substituents (-OMe and/or -NO2) at the 4,4'-position was investigated experimentally and theoretically. The two-photon spectra cross-sections σ(2) DPA were obtained by optical-probing photoacoustic spectroscopy (OPPAS). simulated of derivatives, time-dependent density functional theory within Tamm-Dancoff approximation, agreed well experimental ones. mechanisms enhancement centrosymmetric non-centrosymmetric found to be...

Two-photon absorption for diphenylacetylene derivatives with an electron-donating (ED) or electron-withdrawing (EW) group (DPA-Rs) was investigated by high-sensitivity optical-probing photoacoustic spectroscopy. spectra and two-photon cross sections σ(2) DPA-Rs were successfully obtained. of stronger ED EW groups display more significant red-shifts larger values. Simulated spectra, using time-dependent density functional theory within the Tamm–Dancoff approximation, compared well...

A new display device, SXRD, has been developed for projection displays. SXRD consists of vertical aligned nematic (VAN) liquid crystal and inorganic alignment layers with narrow cell thickness less than 2 μm on uniquely-designed Silicon backplane, featuring high resolution more Full HD, contrast ratio 4000:1 rapid response 5 msec. The devices deliver HD (1920H × 1080V) in 0.78-inch diagonal panel 8.85M (4096H 2160V) 1.55-inch panel. Products using will appear into the market rear TVs, front...

Two-photon absorption spectra and two-photon cross sections of Cl-substituted diphenylacetylenes (ClDPAs) were investigated by optical-probing photoacoustic spectroscopy quantum chemical calculations for the first time. The ClDPAs exhibited intense bands at around 480 nm, which are forbidden one-photon absorption. σ(2) o-, m-, p-ClDPAs 476 nm determined to be 22 ± 1, 23 38 2 GM, respectively. Compared with diphenylacetylene (DPA) (27 GM 472 nm), values o- m-ClDPAs lower, while that p-ClDPA...

A π-type hydrogen bonding between the OH group and π electron is a crucial factor for conformational preference of molecular structure with flexible group. However, information on effect substituent OH/π interaction insufficient. The laser-induced fluorescence (LIF) excitation, dispersed (DF), IR-UV hole-burning, IR dip spectra jet-cooled 2-(4-methoxyphenyl)ethanol were measured first time. Almost all bands observed in spectral region 35 550-36 500 cm-1 LIF excitation spectrum successfully...