- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Radiomics and Machine Learning in Medical Imaging
- Bladder and Urothelial Cancer Treatments
- Health Systems, Economic Evaluations, Quality of Life
- Urologic and reproductive health conditions
- Urinary and Genital Oncology Studies
- Renal cell carcinoma treatment
- Cancer, Lipids, and Metabolism
- Radiopharmaceutical Chemistry and Applications
- Colorectal Cancer Surgical Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- MRI in cancer diagnosis
- Clinical practice guidelines implementation
- Cancer Immunotherapy and Biomarkers
- Economic and Financial Impacts of Cancer
- Statistical Methods in Clinical Trials
- Genital Health and Disease
- Advanced X-ray and CT Imaging
- Advanced Radiotherapy Techniques
- Hormonal and reproductive studies
- Radiation Dose and Imaging
- Radiation Therapy and Dosimetry
- Urinary Bladder and Prostate Research
- Pelvic floor disorders treatments
Istituti di Ricovero e Cura a Carattere Scientifico
2021-2025
IRCCS Ospedale San Raffaele
2018-2025
Vita-Salute San Raffaele University
2018-2025
Memorial Sloan Kettering Cancer Center
2023-2025
Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele
2021-2024
Fondazione Vincenzo Pansadoro
2018-2020
Istituto Nazionale di Fisica Nucleare, Sezione di Milano
2020
University of Minnesota Rochester
2020
Bladder Cancer Advocacy Network
2020
University of Catania
1998-2020
Extended pelvic nodal dissection (ePLND) represents the gold standard for staging in prostate cancer (PCa). Prostate-specific membrane antigen (PSMA) radioguided surgery (RGS) could identify lymph node invasion (LNI) during robot-assisted radical prostatectomy (RARP). To report planned interim analyses of a phase 2 prospective study (NCT04832958) aimed at describing PSMA-RGS RARP. A trial enrolling 100 patients with intermediate- or high-risk cN0cM0 PCa conventional imaging risk LNI >5% was...
To assess the survival outcomes of adjuvant radiation therapy (aRT) versus observation with or without early salvage RT (Obs±esRT) for cN0M0 pN1 PCa and to create a model clinical decision making. We retrospectively identified 1,103 patients after surgery ( 2000-2021) at 18 referral centers. Kaplan-Meier curves, Cox proportional hazards were used. Overall, 670 (61%) had ISUP 4-5 median number positive nodes was 1. On multivariable analyses, ≥3 (HR 2.03,95% CI 1.22-3.37; p=0.006) 5 1.92,95%...
ISUP Grade-Group (GG) is based on the relative proportion of Gleason patterns 3 and 4. We investigated whether absolute pattern 4 volume more strongly associated with advanced stage biochemical recurrence than GG in patients but not 5. Overall, 1171 men received radical prostatectomy. Advanced definitions were extra-prostatic extension (EPE) or seminal vesicle invasion (SVI) nodal (LNI), SVI LNI. explored association between percentage, using logistic Cox regressions. examined incorporating...