A5072518652- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Bladder and Urothelial Cancer Treatments
- Radiomics and Machine Learning in Medical Imaging
- Urologic and reproductive health conditions
- Urological Disorders and Treatments
- MRI in cancer diagnosis
- Health Systems, Economic Evaluations, Quality of Life
- Renal cell carcinoma treatment
- Urinary and Genital Oncology Studies
- Radiopharmaceutical Chemistry and Applications
- Cancer Immunotherapy and Biomarkers
- Genital Health and Disease
- Advanced X-ray and CT Imaging
- Cancer, Lipids, and Metabolism
- Advanced Radiotherapy Techniques
- Cardiac, Anesthesia and Surgical Outcomes
- Venous Thromboembolism Diagnosis and Management
- Radiation Dose and Imaging
- Colorectal Cancer Surgical Treatments
- Cancer Genomics and Diagnostics
- Renal and Vascular Pathologies
- Economic and Financial Impacts of Cancer
- Statistical Methods in Clinical Trials
- Health Promotion and Cardiovascular Prevention
IRCCS Ospedale San Raffaele
2021-2025
Vita-Salute San Raffaele University
2021-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2021-2025
Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele
2021-2025
Memorial Sloan Kettering Cancer Center
2024-2025
Istituto Nazionale di Fisica Nucleare, Sezione di Milano
2020
University of Minnesota Rochester
2020
Extended pelvic nodal dissection (ePLND) represents the gold standard for staging in prostate cancer (PCa). Prostate-specific membrane antigen (PSMA) radioguided surgery (RGS) could identify lymph node invasion (LNI) during robot-assisted radical prostatectomy (RARP). To report planned interim analyses of a phase 2 prospective study (NCT04832958) aimed at describing PSMA-RGS RARP. A trial enrolling 100 patients with intermediate- or high-risk cN0cM0 PCa conventional imaging risk LNI >5% was...
Our aim was to evaluate whether transperineal (TP) MRI-targeted prostate biopsy (TBx) may improve the detection of clinically significant cancer (csPCa), defined as International Society Urological Pathology ≥2, in comparison transrectal (TR) TBx.A multicenter retrospective cohort study comprising patients who underwent MRI-guided conducted. To address possible benefits TP-TBx (PCa) and csPCa, a undergoing were compared TR-TBx. Multivariable logistic regression analyses performed assess...
Guideline recommendations regarding early management of grade group (GG) 2 prostate cancer with confirmatory biopsy (cBx) are not well established. Our aim was to determine which patients GG should undergo cBx before treatment decision-making by evaluating the probability downgrading 1 or no on cBx. This a single-institution retrospective analysis who underwent We modeled having Gleason pattern 4 according magnetic resonance imaging (MRI) Prostate Imaging-Reporting and Data System (PI-RADS)...
Prostate-specific membrane antigen radioguided surgery (PSMA-RGS) might identify lymph node invasion (LNI) in prostate cancer (PCa) patients undergoing extended pelvic dissection (ePLND). The optimal target-to-background (TtB) ratio to define RGS positivity is still unknown.
No AccessJournal of UrologyOriginal Clinical Article31 Jul 2024Management and Oncologic Outcomes Incidental Prostate Cancer After Transurethral Resection the in DenmarkThis article is commented on by following:Editorial Comment Riccardo Leni, Andrew Julian Vickers, Klaus Brasso, Francesco Montorsi, Alberto Briganti, Torben Kjær Nielsen, Andreas Røder, Hein Vincent Stroomberg LeniRiccardo Leni https://orcid.org/0000-0003-0779-0984 Department Epidemiology Biostatistics, Memorial Sloan...
Patients diagnosed with grade group (GG) 1 prostate cancer (PCa) following treatment for benign disease ("incidental" PCa) are typically managed active surveillance (AS). It is not known how their outcomes compare those observed in patients GG1 on biopsy. We aimed at determining whether long-term oncologic of AS PCa differ according to the type diagnosis: incidental versus biopsy detected.
ISUP Grade-Group (GG) is based on the relative proportion of Gleason patterns 3 and 4. We investigated whether absolute pattern 4 volume more strongly associated with advanced stage biochemical recurrence than GG in patients but not 5. Overall, 1171 men received radical prostatectomy. Advanced definitions were extra-prostatic extension (EPE) or seminal vesicle invasion (SVI) nodal (LNI), SVI LNI. explored association between percentage, using logistic Cox regressions. examined incorporating...