A5101508456- Cancer-related molecular mechanisms research
- Ferroptosis and cancer prognosis
- Metal and Thin Film Mechanics
- MXene and MAX Phase Materials
- Corrosion Behavior and Inhibition
- Cancer, Lipids, and Metabolism
- Selenium in Biological Systems
- Complex Network Analysis Techniques
- Heme Oxygenase-1 and Carbon Monoxide
- Traumatic Brain Injury and Neurovascular Disturbances
- Tryptophan and brain disorders
- Topic Modeling
- Glioma Diagnosis and Treatment
- Ginseng Biological Effects and Applications
- Glutathione Transferases and Polymorphisms
- Mitochondrial Function and Pathology
- Autophagy in Disease and Therapy
- Connexins and lens biology
- RNA Research and Splicing
- Advanced Text Analysis Techniques
- Retinal Development and Disorders
- Hippo pathway signaling and YAP/TAZ
Hunan Normal University
2025
Second Affiliated Hospital of Xi'an Jiaotong University
2025
Nanjing University of Aeronautics and Astronautics
2019-2022
Ministry of Industry and Information Technology
2020-2021
Purpose: To study whether radiation-induced bleeding in the bone marrow induced iron accumulation, and subsequently caused ferroptosis granulocyte-macrophage hematopoietic progenitor cells.Materials methods: Male mice were subjected to different doses (0, 4, 8, or 10 Gy) of gamma radiation from a 137Cs source. The changes metabolism ferroptosis-related parameters irradiated accessed with biochemical, histopathological, antibody methods. Hematocytes detected hematology analyzer. counts cells...
Purpose Baicalein (an anti-ferroptosis drug) was recently reported to synergistically improve the survival rate of mice following a high dose total body irradiation with anti-apoptosis and anti-necroptosis drugs. At same time, our group has demonstrated that ferrostatin-1, ferroptosis inhibitor, improves mouse model hematopoietic acute radiation syndrome 60% for 150 days (p < .001). These phenomena suggest inhibition can mitigate damage. In this study, we continued study mechanisms by which...
Accumulating evidence suggests that ionizing radiation (IR)‑induced cataract may be associated with oxidative stress. Nuclear factor erythroid 2‑related 2 (Nrf2) serves as a master regulator of the antioxidant defense system against The present study aimed to investigate effects different doses neutron on Nrf2‑reegulated in rat lens and assess status A total 24 SD rats were randomly divided into following four groups: i) Control group; iis) 0.4 Sv iii) 1.2 iv) 3.6 group. sacrificed 7 days...
Backgrounds: It remains unclear whether radiation-induced haemorrhage in the spleen causes iron accumulation, and subsequently, ferroptosis splenic lymphocytes. In this study, we investigated occurrence of lymphocytes gamma-irradiated mice. Materials Methods: Mice were subjected to gamma radiation from a 137Cs source. Iron, Ferroportin 1, regulatory protein (IRP) levels spleen, serum hepcidin blood measured study change metabolism irradiated spleen. After Ferrostatin 1/LDN193189 was...
Understanding the performance of data mining approach and topic evolution in a certain scientific domain is imperative to capturing key developments facilitating knowledge transfer within across domains. Our research selects linguistics as an exploratory exploits feature maximization (FM) measurement for selection, combined with contrast ratio conduct diachronic analysis domain’s topics. To accurately mine topics obtain optimal clustering model we exploit integrated method associated deep...