A5101717204- Glioma Diagnosis and Treatment
- Meningioma and schwannoma management
- Neurofibromatosis and Schwannoma Cases
- Neurological disorders and treatments
- Spinal Fractures and Fixation Techniques
- Traumatic Brain Injury and Neurovascular Disturbances
- Cerebrospinal fluid and hydrocephalus
- Vascular Malformations Diagnosis and Treatment
- Spine and Intervertebral Disc Pathology
- Pituitary Gland Disorders and Treatments
- Parkinson's Disease Mechanisms and Treatments
- Head and Neck Surgical Oncology
- Botulinum Toxin and Related Neurological Disorders
- Adrenal and Paraganglionic Tumors
- Sarcoma Diagnosis and Treatment
- Bone Tumor Diagnosis and Treatments
- Genetic Neurodegenerative Diseases
- Intracranial Aneurysms: Treatment and Complications
- Spinal Dysraphism and Malformations
- Radiation Dose and Imaging
- Cervical and Thoracic Myelopathy
- Reconstructive Surgery and Microvascular Techniques
- Intracerebral and Subarachnoid Hemorrhage Research
- Fetal and Pediatric Neurological Disorders
- Neurosurgical Procedures and Complications
All India Institute of Medical Sciences
2016-2025
University of Regina
2024
All India Institute of Medical Sciences Bhopal
2011-2023
University of New Brunswick
2023
All India Institute of Medical Sciences Raipur
2011-2023
Koneru Lakshmaiah Education Foundation
2022
Indian Institute of Technology Mandi
2020
National Neurosciences Centre
2020
Wayne State University
2019
Detroit Medical Center
2019
POST, MELVIN M.D.; SILVER, RONALD SINGH, MANMOHAN M.D.Editor(s): M.D. Author Information
In 22 acromegalic patients, microradiographic studies of biopsy samples from rib cortex Showed the proportion forming surfaces was greater than resorbing although both were increased (p < 0.01) and correlated 0.001) with serum concentration immunoreactive growth hormone; in 4 similar predominantly trabecular bone iliac crest or femoral neck showed that predominated. 26 transmission scanning an 125I source at midradius diameter 0.05) cortical mass normal (17 patients) (9 patients); these same...
Cerebral oedema is associated with significant neurological damage in patients traumatic brain injury. Bradykinin an inflammatory mediator that may contribute to cerebral by increasing the permeability of blood-brain barrier. We evaluated safety and effectiveness non-peptide bradykinin B2 receptor antagonist Anatibant treatment During course trial, funding was withdrawn sponsor. Adults injury a Glasgow Coma Scale score 12 or less, who had CT scan showing intracranial abnormality consistent...
Background. Vasospasm plays a major role in the morbidity and mortality after aneurysmal subarachnoid hemorrhage (aSAH). The preliminary studies suggest that statins protect against cerebral vasospasm. Objective. aim of study was to determine simvastatin preventing clinical vasospasm improving functional outcome patients with aSAH. Methods. All aSAH admitted within 96 h ictus were randomized receive either Simvastatin or placebo – 80 mg/day for 14 days. Thirty eight recruited study- 19...
Abstract Primary CNS Vasculitis (PCNSV) is a rare inflammatory disorder affecting the blood vessels of central nervous system. Patients present with combination headaches, seizures, and focal neurological deficits. There usually diagnostic delay. Treatment based on observational studies expert opinion. Our objective was to identify clinical, laboratory, neuroimaging, pathologic or management-related associations 2 year outcome in patients primary vasculitis. We conducted cohort study at...
Abstract Background and Objectives: Intracerebral hemorrhage (ICH) is associated with high mortality morbidity. Uncertainty still exists regarding the benefit of surgery in management supratentorial spontaneous ICH (sICH), especially basal ganglia thalamus. Studies have not shown clinical early surgical compared to best medical plus delayed surgery, when necessary. Our aim was compare efficacy different neurosurgical interventions alone. Methods: We conducted a single-center, retrospective...
Gliosarcoma is a rare variant of glioblastoma multiforme (GBM) with similar clinical presentation and prognosis but distinct genetic profile. The clinicopathological features 22 cases gliosarcoma were analyzed respect to age, sex, KPS score, operative diagnosis, extent resection histopathological subtype (predominantly sarcomatous [PS], predominantly gliomatous [PG] or mixed). Twelve PS, six PG four mixed. histological did not correlate the diagnosis; however, it significantly (P=0.014). In...
Background Hypoglossal schwannomas are rare intracranial neoplasms. Microsurgical resection with the goal of cure is aim management but associated a high rate postoperative morbidity. Objective The objective study was to outline clinical presentation, radiologic characteristics, surgical techniques, morbidity, and long-term follow-up results for hypoglossal schwannomas. Methods Patients treated schwannoma at Department Neurosurgery tertiary-level referral institution from January 2001 until...
Molecular and clinical characteristics of pediatric meningiomas are poorly defined. Therefore, we analyzed clinical, morphological molecular profiles meningiomas. Forty from January 2002 to June 2015 were studied. 1p36, 14q32 22q-deletion assessed by fluorescent in situ hybridization mutations most relevant exons AKT, SMO, KLF4, TRAF pTERT using sequencing. Expression GAB1, stathmin, progesterone receptor (PR), p53 along with MIB-1 LI was examined immunohistochemistry. There 36 sporadic four...
Ependymomas are relatively rare glial tumours, whose pathogenesis is not well elucidated. They enigmatic tumours that show site-specific differences in their biological behaviour. Recent studies have hypothesized ependymoma cancer stem cells (CSCs) derived from radial glia and express cell markers such as nestin, which associated with a poor prognosis. CSCs reside 'vascular niches', where endothelial molecular signals like vascular growth factor (VEGF) play an important role survival....