A5084027661- Hydrogen's biological and therapeutic effects
- Anesthesia and Neurotoxicity Research
- Acute Ischemic Stroke Management
- Biochemical effects in animals
- Traumatic Brain Injury and Neurovascular Disturbances
- Orthopedic Infections and Treatments
- Intracranial Aneurysms: Treatment and Complications
- Stroke Rehabilitation and Recovery
- Hippo pathway signaling and YAP/TAZ
- Neuroscience of respiration and sleep
- Bone fractures and treatments
- MicroRNA in disease regulation
- Nerve injury and regeneration
- Gastroesophageal reflux and treatments
- Cervical and Thoracic Myelopathy
- Surgical site infection prevention
- Voice and Speech Disorders
- Dysphagia Assessment and Management
- Axon Guidance and Neuronal Signaling
- Cerebrovascular and Carotid Artery Diseases
- Spinal Fractures and Fixation Techniques
- Spine and Intervertebral Disc Pathology
- Neurogenesis and neuroplasticity mechanisms
Loma Linda University
2015-2022
Czech Academy of Sciences, Institute of Physiology
2018
Loma Linda University Medical Center
2016
Kaiser Permanente Fontana Medical Center
2016
After ischemic stroke, apoptosis of neurons is a primary factor in determining outcome. Wnt3a naturally occurring protein that has been shown to have protective effects the brain for traumatic injury. Although wnt3a investigated phenomena neurogenesis, anti-apoptosis, and anti-inflammation, it never as therapy stroke. We hypothesized potential neuroprotective agent would reduce infarction improve behavior following stroke by attenuating neuronal promoting cell survival through...
Modern warfare has caused a large number of severe extremity injuries, many which become infected. In more recent conflicts, pattern co-infection with Acinetobacter baumannii and methicillin-resistant Staphylococcus aureus emerged. We attempted to recreate this in an animal model evaluate the role vascularity contaminated open fractures. Historically, it been observed that infected bones frequently appear hypovascular, but association bone infection not examined models. Adult rats underwent...
A total of 35 adult male Sprague-Dawley rats (weighing 300-320 g, 8-10 weeks age) were used in the proposed study.All experiments approved by Institutional Animal Care and Use Committee Loma Linda University, USA (Approval No. 8160016) May 2016, complied with
Recent cerebrovascular recanalization therapy clinical trials have validated delayed in patients outside of the conventional window. However, a paucity information on pathophysiology and favorable outcomes remains. Since macrophages are extensively studied tissue repair, we anticipate that they may play critical role after ischemic stroke. In adult male Sprague-Dawley rats, two stroke groups were used: permanent middle cerebral artery occlusion (pMCAO) at 3 days following (rMCAO). To...