A5004431042- Pancreatic and Hepatic Oncology Research
- Esophageal and GI Pathology
- Hepatocellular Carcinoma Treatment and Prognosis
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Plasmonic and Surface Plasmon Research
- Advanced biosensing and bioanalysis techniques
- Gastric Cancer Management and Outcomes
- Magnetic Properties and Applications
- AI in cancer detection
- Cancer Genomics and Diagnostics
- Musculoskeletal synovial abnormalities and treatments
- Esophageal Cancer Research and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Gallbladder and Bile Duct Disorders
- Magnetic Properties of Alloys
- Dysphagia Assessment and Management
- Photonic and Optical Devices
- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Magnetic properties of thin films
- Congenital Diaphragmatic Hernia Studies
- Gastroesophageal reflux and treatments
- Data Quality and Management
- Vascular Malformations and Hemangiomas
- Autoimmune and Inflammatory Disorders
Keio University
2000-2025
Nippon Medical School
2020-2025
Cancer Institute (WIA)
2024
Japanese Foundation For Cancer Research
2022-2024
Keio University Hospital
2020-2024
The University of Tokyo
2022
Social Insurance Saitama Chuo Hospital
2018
Shinshu University
2011
Toppan (Japan)
2003
Hokkaido University
1981
Abstract Robust underwater adhesion is challenging because a hydration layer impedes the interaction between substrates and adhesives. Phenolic adhesives inspired by marine creatures such as mussels were extensively studied, but these have not reached strength substrate diversity of Man-made dry Here, we report class ultrastrong with molecular phenolic designs extending beyond what nature has produced. These non-canonical polymers show versatile on various materials, strengths exceeding 10...
Plasmon-induced hot-electron generation has recently received considerable interest and been studied to develop novel applications in optoelectronics, photovoltaics green chemistry. Such hot electrons are typically generated from either localized plasmons metal nanoparticles or propagating patterned nanostructures. Here we simultaneously generate these heterogeneous plasmon-induced exploit their cooperative interplay a single metal-semiconductor device demonstrate, as an example,...
Abstract Surface plasmon resonance is a well-established technology for real-time highly sensitive label-free detection and measurement of binding kinetics between biological samples. A common drawback, however, surface the necessity far field angular resolved specular reflection, which increases size as well requiring precise calibration optical apparatus. Here we present an alternative optoelectronic approach in plasmonic sensor integrated within photovoltaic cell. Incident light generates...
Abstract Purpose To achieve a historical perspective, the chronological changes in primary liver cancer over 20-year period were investigated at single institution, focusing on shifts etiology and impact imaging pathological findings using The Liver Imaging Reporting Data System. Materials methods A retrospective study of surgically resected 680 patients from 2001 to 2020 resulted 434 with 482 nodules being analyzed. Dynamic contrast-enhanced computed tomography System 2018 classification...
Abstract Introduction: Circulating tumor cells (CTCs) are expected to provide various types of information about tumors. However, their low abundance in the bloodstream poses a challenge obtaining sufficient quantity for analysis. For detecting genetic mutations, circulating DNA (ctDNA) has higher sensitivity. We previously reported that sensitivity RAS mutation using ELESTA CROSSORTER (AFI Technology) is only 10.3%. Thus, we improved our system enhance gene mutations CTC, and compared...
Abstract Background Loss of skeletal muscle mass is a prognostic factor after surgery for gastrointestinal cancers. The treatment perihilar cholangiocarcinoma (PHC) highly invasive surgery. Biliary drainage and portal vein embolization, which can prolong the preoperative waiting time (PWT), are often required before Assuming that change during PWT, we investigated clinical effect on surgical outcomes PHC. Methods We retrospectively reviewed medical records 89 patients who underwent curative...
Introduction: Pancreatic cancer (PC) is highly malignant and metastatic; however, bone metastases are rare. Although the effectiveness of conversion surgery for distant PC has been reported in a few cases, there no reports on surgical resection metastases. Here, we report case long-term survival after metastasis from PC. Patient concerns: A 60-year-old woman underwent pancreaticoduodenectomy neoadjuvant chemoradiotherapy pancreatic head cancer. At 28 months surgery, multiple lung were...
Abstract Background Surgery is indicated for symptomatic epiphrenic esophageal diverticula. Based on the features of a case, thoracoscopic or laparoscopic approaches may be used. Epiphrenic diverticula are often associated with motility disorders, but cases reflux esophagitis have rarely been reported. In this report, we describe case an diverticulum esophagitis, which was successfully treated by diverticulectomy and fundoplication. Case presentation A 69-year-old man visited hospital chief...
Achalasia is an esophageal motility disorder that presents as dysphagia and severely affects quality of life. An myotomy has been the golden standard for treatment. Peroral endoscopic (POEM) a first-line therapy acceptable outcome. However, after clinical failure POEM, appropriate second-line rather controversial. Here, we present first published case in English patient who was successfully treated using laparoscopic Heller (LHM) with Dor fundoplication following unsuccessful POEM.A...
<title>Abstract</title> <italic><bold>Purpose:</bold></italic> With advances in chemotherapy, conversion surgery is often performed for initially unresectable colorectal cancer liver metastasis (CLM). However, unexpected postoperative failure (POLF) sometimes associated with chemotherapy-related hepatotoxicity following long-term chemotherapy. We aimed to identify predictive factors POLF after CLM. <italic><bold>Methods:</bold></italic> retrospectively identified 774 consecutive patients who...
Abstract We report a case of reactive lymphoid hyperplasia (RLH) mimicking colorectal liver metastases (CRLM) on preoperative workup that was clinically indistinguishable. A 78-year-old woman found to have locally-advanced sigmoid cancer (T4), and then treated with radical sigmoidectomy. One year after the surgery, plain computed tomography (CT) revealed low-density area in right hepatic lobe. Metastatic tumors could not be ruled out CT/ magnetic resonant imaging (MRI) positron emission...
症例1は47歳の女性で,膵癌を疑う膵腫瘍に対し亜全胃温存膵頭十二指腸切除を施行した.膵尾部は脂肪置換され残膵断端の主膵管は同定できなかったため,膵管空腸吻合をせず膵断端を縫合し挙上空腸と膵実質を密着縫合した.術後に膵液漏は認めたが内分泌機能は良好で術後第33病日に退院した.術後2年5か月無再発で耐糖能良好である.症例2は46歳の男性で,慢性膵炎の既往がある膵神経内分泌腫瘍に対して亜全胃温存膵頭十二指腸切除を施行した.膵実質は脂肪置換され主膵管を同定できなかった.断端迅速組織診断にてランゲルハンス氏島細胞のみを認め主膵管は退縮していたため,膵断端を縫合閉鎖して残膵空置とした.術後Cペプチドの軽度低下を認め,ヒューマログ2-2-2で経過観察中である.膵体尾部脂肪置換に対する膵頭十二指腸切除は,残膵空置して可能なかぎりランゲルハンス氏島を残すことで膵全摘よりも良好な耐糖能を維持できると考えられた.
症例は80歳，女性．肛門縁から15cmの全周性2型腫瘍に対し高位前方切除術を施行した．術後第1病日より仙骨前面ドレーンから多量の乳縻様排液を認めリンパ漏と診断，禁食・利尿剤投与などで改善傾向となり第23病日に退院となった．術後1カ月頃よりリンパ漏が増悪し，オクトレオチドや利尿剤を投与するも改善に乏しく適宜腹水穿刺を施行した．術後112病日に診断的治療として両側鼠径リンパ節穿刺からリピオドールによるリンパ管造影を施行，腹部大動脈分岐部直上左側の外側大動脈リンパ節周囲から造影剤漏出を認め瘻孔部位と考えられた．術後151日目のCTで著明な腹水減少が得られ，現在，術後3年で無再発生存中である．保存的治療に反応しない消化管術後難治性リンパ漏に対しては外科的治療が推奨されているが，奏効率は高くない．リピオドールによる治療的リンパ管造影は，消化管術後難治性リンパ漏に対して有用な治療手段となり得る．
The new repair of the clear defects on half-tone PSM (EAPSM) was proposed. Ga (gallium) ions were implanted by FIB area adjacent to carbon films formed defects. ion SiO<sub>2</sub> substrate showed semi-transparency at KrF and ArF wavelengths. lithography simulations layouts designed for defect-repaired endorsed concept repair. implantation optimized using AIMS AFM measurements transmittance etched depth surface. authors applied this method programmed EAPSMs. analysis that deviation CD...
Magnetic properties and magnetotransport of Ni/TbFeCo/Ni trilayers have been studied. Due to the antiferromagnetic exchange coupling between Tb FeCo, antiparallel aligned spins FeCo Ni can be obtained at interfaces. Interesting hysteresis loops are observed for trilayers. Most importantly, magnetoresistance has spin flop where layer tend their moment aligned. Such kind explained by formation a sharp “domain wall” composing 3 <i xmlns:mml="http://www.w3.org/1998/Math/MathML"...