A5028911269- Advanced Polymer Synthesis and Characterization
- Hydrogels: synthesis, properties, applications
- Advanced Sensor and Energy Harvesting Materials
- Electrospun Nanofibers in Biomedical Applications
- Viral Infectious Diseases and Gene Expression in Insects
- 3D Printing in Biomedical Research
- Innovative Microfluidic and Catalytic Techniques Innovation
- biodegradable polymer synthesis and properties
- Electrochemical sensors and biosensors
- Additive Manufacturing and 3D Printing Technologies
- Neurobiology and Insect Physiology Research
- Photopolymerization techniques and applications
University of Colorado Boulder
2017-2025
While many hydrogels are elastic networks crosslinked by covalent bonds, viscoelastic with adaptable crosslinks increasingly being developed to better recapitulate time and position-dependent processes found in tissues. In this work, 1,2-dithiolanes presented as dynamic photocrosslinkers of hydrogels, resulting disulfide bonds throughout the hydrogel that respond multiple stimuli. Using lipoic acid a model dithiolane, formed under physiological conditions, enabling cell encapsulation via an...
Abstract Granular synthetic hydrogels are useful bioinks for their compatibility with a variety of chemistries, affording printable, stimuli‐responsive scaffolds programmable structure and function. Additive manufacturing microscale hydrogels, or microgels, allows the fabrication large cellularized constructs percolating interstitial space, providing platform tissue engineering at length scales that inaccessible by bulk encapsulation where transport media other biological factors limited...
Abstract Hydrogels are often synthesized through photoinitiated step‐, chain‐, and mixed‐mode polymerizations, generating diverse network topologies resultant material properties that depend on the underlying connectivity. While many photocrosslinking reactions available, few afford controllable connectivity of hydrogel network. Herein, a versatile photochemical strategy is introduced for tuning structure poly(ethylene glycol) (PEG) hydrogels using macromolecular monomers functionalized with...
Proteases are involved in almost every important cellular activity, from embryonic morphogenesis to apoptosis. To study protease activity