A5014708711- Traditional Chinese Medicine Studies
- Venous Thromboembolism Diagnosis and Management
- Nanoparticle-Based Drug Delivery
- Free Radicals and Antioxidants
- Streptococcal Infections and Treatments
- Synthesis and Biological Evaluation
- Quinazolinone synthesis and applications
- Heparin-Induced Thrombocytopenia and Thrombosis
- Sphingolipid Metabolism and Signaling
- Photoacoustic and Ultrasonic Imaging
- Medicinal Plants and Bioactive Compounds
- Pharmacological Effects of Natural Compounds
- Cancer, Hypoxia, and Metabolism
- Synthesis and biological activity
- Nanoplatforms for cancer theranostics
- Eicosanoids and Hypertension Pharmacology
Chengdu University of Traditional Chinese Medicine
2023-2024
Acute lung injury (ALI) is a severe and often fatal pulmonary disease. Current treatments for ALI acute respiratory distress syndrome (ARDS) are limited. Natural product metabolites have shown promise as therapeutic alternatives. However, the effects of Licochalcone B (LCB) on largely unknown.We investigated LCB lipopolysaccharide-challenged mice human microvascular endothelial cells. Cell viability, apoptosis, ROS production were assessed. Lung tissue histopathology oxidative stress...
To investigate the inhibitory effect of EVO on colorectal cancer (CRC) growth and further explore potential mechanism involving RTKs-mediated PI3K/AKT/p53 signaling pathway.
Conventional inorganic semiconductor nanoparticles have emerged as photothermal agents in therapy and sonosensitizers sonodynamic therapy. However, their weak drug-loading capabilities the deficient techniques for multifunctional limit applications. A bismuth-based gold-crowned nanocomposite (BACN) was rationally designed successfully synthesized could then be used to prepare nanoplatforms with excellent biocompatibilities synergistic real-time imaging. Because of constituent gold pyridine,...
After orthopedic surgeries, such as hip replacement, many patients are prone to developing deep vein thrombosis (DVT), which in severe cases can lead fatal pulmonary embolism or major bleeding. Clinical intervention with high-dose anticoagulant therapy inevitably carries the risk of Therefore, a targeted drug delivery system that adjusts local DVT lesions and potentially reduces dosage toxic side effects important. In this study, we developed platelet-derived nanoplatform (AMSNP@PM-rH/A) for...
Protein polypeptides and polysaccharides, the indispensable macromolecular active components in traditional Chinese medicine, are widely found medicine decoction after of medicine. However, through oral administration, these macromolecules digested by stomach intestine thus fail to be absorbed prototype. This is inconsistent with actual clinical efficacy decoction. According modern research, new phase structures effects emerge during but change law caused interaction among relationship...
Abstract Lung cancer is one of the malignant tumors with leading morbidity and mortality worldwide. H 2 O an important oxidant, lethal to tumor cells. The present study aimed explore new higher‐H ‐content faster‐H ‐release rate carbamide peroxide (CP) compounds for treatment lung cancer. CP added benzoic acid termed CP−B was applied in research. Fenton reaction used determine content release by degrading organic small molecule dyes. results showed that could be decolorized 200 mg/L RhB...