Othman F. Abdelzaher

ORCID: 0000-0003-0101-2962
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About
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Research Areas
  • Aquaculture Nutrition and Growth
  • Aquatic life and conservation
  • Aquaculture disease management and microbiota
  • Nanoparticles: synthesis and applications
  • Reproductive Biology and Fertility
  • Mesenchymal stem cell research
  • Sperm and Testicular Function
  • Pancreatic function and diabetes
  • Sexual Differentiation and Disorders
  • Natural Products and Biological Research
  • Congenital heart defects research
  • Heavy Metal Exposure and Toxicity
  • Renal and related cancers
  • Fish Biology and Ecology Studies
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Testicular diseases and treatments
  • Assisted Reproductive Technology and Twin Pregnancy
  • Reproductive biology and impacts on aquatic species
  • Echinoderm biology and ecology
  • Pomegranate: compositions and health benefits

Al-Azhar University
2018-2025

Background: Pyroptosis is an inflammatory programmed cell death accompanied by activation of inflammasomes and maturation pro-inflammatory cytokines interleukin-1β (IL-1β) IL-18. closely linked to the development diabetic cardiomyopathy (DC). Pomegranate peel extract (PPE) exhibits a cardioprotective effect due its antioxidant anti-inflammatory properties. This study aimed investigate underlying mechanisms protective PPE on myocardium in rat model DC determine molecular mechanism. Methods:...

10.3389/fphar.2023.1166653 article EN cc-by Frontiers in Pharmacology 2023-03-28

The formulator of aquatic diets is part a continuous search for alternative protein sources instead depreciated fish meal. utilization zooplankton as feed ingredient an interesting trend due to their high-quality content and abundance essential nutrients. current study aims investigate the effects partial total replacement meal (FM) by Dahpnia magna (DMM) on growth performance, utilization, histological, economic status mullet, M. cephalus, larvae. In addition control diet, 100% FM, D0, four...

10.3390/su13137093 article EN Sustainability 2021-06-24

Fishmeal is the most expensive feedstuff in aquafeed and one of environmentally limiting factor aquaculture development. Therefore, search for alternative protein sources a continuous process. The present feeding trial was conducted to evaluate effects replacing fishmeal with zooplankton biomass meal (ZBM) on growth performance, nutrient utilization, intestine, liver histological changes grey mullet, Mugil cephalus (initial weight 0.10 ± 0.01 g). Five isoproteic (35% crude protein)...

10.3390/fishes6030038 article EN cc-by Fishes 2021-09-10

Abstract The current study aimed to evaluate growth performance, digestive enzyme activities, antioxidant status, nonspecific immune response and intestinal histological status of red tilapia fed Daphnia meal (DM) as a substitute for fishmeal (FM). Hybrid ( Oreochromis mossambicus × aureus ) fry (0.54 ± 0.05 g fish −1 was allocated in nylon haba cages (100 m −3 2 weeks an acclimation period. were divided into five groups (three replicates each). experimental diets prepared by replacing FM...

10.1111/jpn.13925 article EN Journal of Animal Physiology and Animal Nutrition 2024-02-02

In this study, a sustainable and eco-friendly method was used to prepare zinc oxide nanoparticles (ZnO-NPs) using sea cucumber aqueous extract. Then, ZnO-NPs were characterized by instrumental analysis (UV-vis, HR-TEM, XRD, FT-IR, DLS) evaluated for their possible antibacterial, antifungal, insecticidal activities. Additionally, the toxicity of in vivo against Nile Tilapia (Oreochromis niloticus). The collected from Gulf Suez (Red Sea) at Al-Ain Al-Sokhna coast Egypt identified as Holothuria...

10.3390/separations10030173 article EN cc-by Separations 2023-03-03

The future of aquaculture development is directed toward high intensification to overcome the decline in natural fishing and provide enough protein for increasing world population. spread production requires search high-quality, new efficient feed ingredients with low cost sustainable importance. Therefore, current study aimed detect effects partial or total replacement fishmeal amphipod meal, Gammarus pulex, on growth performance, survival percent, utilization, histological alteration...

10.3390/jmse9121336 article EN cc-by Journal of Marine Science and Engineering 2021-11-27

Abstract Fishmeal substitution with sustainable feed sources is highly essential towards production. This study aimed to investigate the effects of substituting fishmeal (FM) Daphnia magna biomass meal (DBM) or zooplankton (ZBM) on growth performance, liver and intestinal histology, gut bacterial abundance stress tolerance Nile tilapia , Oreochromis niloticus fry. fry (0.23 ± 0.04 g) were randomly assigned five groups three replicates. The control diet comprised 300 g/kg FM, FM was...

10.1111/jpn.13991 article EN mit Journal of Animal Physiology and Animal Nutrition 2024-05-29

Oncotherapeutics like doxorubicin can affect male gonads; as a result, it leads to infertility. This work was conducted demonstrate the toxic effects of on testes albino rats. Fifty rats aged 5-7 weeks were used in this study. The animals randomly separated into 5 sets (each set containing ten rats). Group I received saline (i.p.) for 4 weeks. II given (DOX), mg/kg BW once/week Groups III and IV treated same way DOX group, left one week without medication, then injected with mesenchymal...

10.1155/2021/9979670 article EN cc-by BioMed Research International 2021-08-06

The marine environment is a rich source of bioactive compounds. Therefore, the sea cucumber was isolated from Red Sea at Al-Ain Al-Sokhna coast and it identified as surf redfish (Actinopyga mauritiana). aqueous extract utilized an ecofriendly, novel sustainable approach to fabricate zinc oxide nanoparticles (ZnO-NPs). biosynthesized ZnO-NPs were physico-chemically characterized evaluated for their possible antibacterial insecticidal activities. Additionally, safety in non-target organism...

10.3390/md21080437 article EN cc-by Marine Drugs 2023-08-02

The role of hyaluronic acid (HA) as a 'physiologic selector' is also well recognized in vitro: it has been demonstrated that spermatozoa bind to immobilized HA vitro are those having completed their plasma membrane remodelling, and cytoplasmic meiotic maturation. Sperm selection using expected increase the implantation rate intracytoplasmic sperm injection (ICSI) cycles. This work was designed evaluate an alternative product for slowing motility contains measures its outcomes: fertilization...

10.1017/s0967199422000685 article EN Zygote 2023-01-23

Nanoparticles (NPs) not only offer a great possibility for biomedical application, pharmaceutics, but also may be used novel diagnostic and therapeutic approaches.Currently, there are no data available regarding to what extent the degree of toxicity gold nanoparticles (AuNSs).This study aimed investigate histopathological ultrastructural effect AuNSs size on liver kidney female pregnant rats.To achieve that 10 nm, 25nm 50 nm were Interperitoneally injected in rats at 48 hr during rat...

10.21608/absb.2018.33816 article EN Al-Azhar Bulletin of Science 2018-12-01

The present work investigates the outcome of Fresh Testicular Biopsy in Comparison to Histopathological Examination NOA Patients.In current study, there were nine discordant instances (16.9%) between andrology lab and histology.Histopathology characterised these cases as hypospermatogenesis, but reported one case SCO, three spermatocyte, five late spermatid.To our knowledge, no study done before examine biopsy from patients who have negative sperm retrieval a fresh examination on side...

10.21608/eajbsz.2023.295691 article EN cc-by Egyptian Academic Journal of Biological Sciences. B, Zoology 2023-04-21
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