ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPreparation and Properties of Serum Plasma Proteins. IV. A System for the Separation into Fractions Protein Lipoprotein Components Biological Tissues Fluids1a,b,c,dE. J. Cohn, L. E. Strong, W. Hughes, D. Mulford, N. Ashworth, M. Melin, H. TaylorCite this: Am. Chem. Soc. 1946, 68, 3, 459–475Publication Date (Print):March 1, 1946Publication History Published online1 May 2002Published inissue 1 March...

A previously unknown rigid helical structure of zinc oxide consisting a superlattice-structured nanobelt was formed spontaneously in vapor-solid growth process. Starting from single-crystal stiff nanoribbon dominated by the c-plane polar surfaces, an abrupt structural transformation into led to formation uniform nanohelix due lattice rotation or twisting. The made two types alternating and periodically distributed long crystal stripes, which were oriented with their c axes perpendicular each...

Abstract Zinc oxide, an important semiconducting and piezoelectric material, has three key characteristics. First, it is a semiconductor, with direct bandgap of 3.37 eV large excitation binding energy (60 meV), exhibits near‐UV emission transparent conductivity. Secondly, due to its non‐centrosymmetric symmetry, piezoelectric, which phenomenon in building electro‐mechanical coupled sensors transducers. Finally, ZnO bio‐safe bio‐compatible, can be used for biomedical applications without...

Bending of polar-surface-dominated (PSD) nanobelts ZnO can be explained by one two processes: electrostatic neutralization the dipole moment via deformation (called an polar charge model) or imbalances between surface tensions surface-termination induced stresses. This article presents experimental data on structural features nanorings and nanobows formed bending single-crystal, PSD nanobelts. Our exclusively support model as dominant mechanism for bending.

To fabricate quantum dot arrays with programmable periodicity, functionalized DNA origami nanotubes were developed. Selected staple strands biotin-labeled to form periodic binding sites for streptavidin-conjugated dots. Successful formation of periods 43 and 71 nm demonstrates precise, programmable, large-scale nanoparticle patterning; however, limitations in array periodicity also observed. Statistical analysis AFM images revealed evidence steric hindrance or site bridging that limited the...

Semiconducting oxide nanobelts of ZnO have been sectioned and manipulated, for microelectromechanical systems, using an atomic force microscopy probe. Structurally modified demonstrate potential nanocantilever based technologies. With dimensions ∼35–1800 times smaller than conventional cantilevers, the nanocantilevers are expected to improved physical, chemical, biological sensitivity scanning probe sensor applications.

The complete crystal structure of Rochelle salt (sodium potassium tartrate tetrahydrate) has been determined by Fourier and Patterson methods. Some the difficulties in application these methods are discussed. molecule is found to lie approximately three planes, planes each half being inclined at 60° plane carbon atoms. molecules bonded sodium atoms both directly through medium water molecules. If preserve their customary tetrahedral ‘ bonding ’ it necessary suppose that one carboxyl groups...

Abstract DNA is a compelling alternative to non-volatile information storage technologies due its density, stability, and energy efficiency. Previous studies have used artificially synthesized store data automated next-generation sequencing read it back. Here, we report digital Nucleic Acid Memory (dNAM) for applications that require limited amount of high redundancy, copy number. In dNAM, encoded by selecting combinations single-stranded with (1) or without (0) docking-site domains. When...

An experimental procedure is presented for the controlled synthesis and manipulation of ZnO nanorings nanobows at high purity large yield. Atomic force microscopy nanostructures demonstrates their mechanical toughness flexibility. Extensive bending suggests an extremely deformation limit with potential building ultrasensitive electromechanical coupled nanoscale sensors, transducers, resonators.

In this paper, a bulk acoustic resonator based on ZnO belts is demonstrated. This device shows great deal of promise in applications as an electronic filter and mass sensor. The fabricated was characterized using vector network analysis, both the first third harmonics resonance were observed at approximately 247 754 MHz, respectively. A one-dimensional Krimholt−Leedom−Matthaei model utilized to predict resonant frequency confirm behavior.

Nonenzymatic catalytic substrates have been engineered using toehold-mediated DNA strand displacement, and their programmable applications range from medical diagnosis to molecular computation. However, the complexity, stability, scalability, sensitivity of those systems are plagued by network leakage. A novel way suppress leakage is increase its energy barrier through four-way branch migration. Presented here, we designed multi-arm junction that simultaneously exploit migration, with a...

A promising application of DNA self-assembly is the fabrication chromophore-based excitonic devices. brick assembly a compelling method for creating programmable nanobreadboards on which chromophores may be rapidly and easily repositioned to prototype new devices, optimize device operation, induce reversible switching. Using nanobreadboards, we have demonstrated each these functions through construction operation two different AND logic gates. The modularity high chromophore density...

DNA origami templated self-assembly has shown its potential in creating rationally designed nanophotonic devices a parallel and repeatable manner. In this investigation, we employ multiscaffold approach to fabricate linear waveguides of 10 nm diameter gold nanoparticles. This provides independent control over nanoparticle separation spatial arrangement. The were characterized using atomic force microscopy far-field polarization spectroscopy. work path toward large-scale plasmonic circuitry.

We introduce a novel probe structure for the atomic force microscope. The has sharp tip placed on micromachined membrane with an integrated displacement sensor, diffraction-based optical interferometer. use this in microscope to directly measure transient interaction forces between and sample when operating dynamic mode. form images related viscoelasticity adhesion of samples by recording salient features individual tap signals. also produce tapping mode topography order magnitude faster...

Fluorescence resonance energy transfer (FRET) is a promising means of enabling information processing in nanoscale devices, but dynamic control over exciton pathways required. Here, we demonstrate the operation two complementary switches consisting diffusive FRET transmission lines which flow controlled by DNA. Repeatable switching accomplished removal or addition fluorophores through toehold-mediated strand invasion. In principle, these can be networked to implement any Boolean function.

Locked nucleic acids (LNAs) are conformationally restricted RNA nucleotides. Their increased thermal stability and selectivity toward their complements make them well-suited for diagnostic therapeutic applications. Although the structural thermodynamic properties of LNA-LNA, LNA-RNA, LNA-DNA hybridizations known, kinetic effects incorporating LNA nucleotides into DNA strand displacement systems not. Here, we thoroughly studied kinetics as a function number position in oligonucleotides. When...

DNA strand displacement systems have transformative potential in synthetic biology. While powerful examples been reported nanotechnology, such are plagued by leakage, which limits network stability, sensitivity, and scalability. An approach to mitigate leakage is applicable biology, introduce mismatches complementary fuel sequences at key locations. However, this method overlooks nuances the secondary structure of substrate that impact reaction kinetics systems. In an effort quantify on we...

Lifetimes and operational performance were investigated for a DNA nanomachine linear probe in human serum blood to elucidate design principles future biomedical applications of DNA-based devices.

Abstract DNA has emerged as a promising material to address growing data storage demands. We recently demonstrated structure-based approach where probes are spatially oriented on the surface of origami and decoded using DNA-PAINT. In this approach, larger structures could improve efficiency reading writing data. However, require long single-stranded scaffolds that not commonly available. Here, we report engineering novel longer scaffold designed produce rectangle needed expand origami-based...

Abstract One of the obstacles hindering acceptance polymer composites in civil engineering applications is susceptibility polymeric matrix to degradation that initiated by moisture, temperature, and corrosive chemical environments. The objective this study was characterize physical changes resins following exposure these Resin systems studied were vinyl ester isophthalic polyester, both which are proposed for use construction applications. Unreinforced free films exposed water, alkaline...

To bring real-world applications of DNA nanostructures to fruition, advanced microscopy techniques are needed shed light on factors limiting the availability addressable sites. Correlative microscopy, where two or more microscopies combined characterize same sample, is an approach overcome limitations individual techniques, yet it has seen limited use for nanotechnology. We have developed accessible strategy high resolution, correlative DNA-based points accumulation imaging in nanoscale...