A5055315511- Advanced Sensor and Energy Harvesting Materials
- Shoulder Injury and Treatment
- Shoulder and Clavicle Injuries
- Electrospun Nanofibers in Biomedical Applications
- Nerve Injury and Rehabilitation
- Dielectric materials and actuators
- Muscle Physiology and Disorders
- Tissue Engineering and Regenerative Medicine
- Bone Tissue Engineering Materials
- Conducting polymers and applications
- Hydrogels: synthesis, properties, applications
- Exercise and Physiological Responses
- Polymer Nanocomposite Synthesis and Irradiation
- Knee injuries and reconstruction techniques
- Protease and Inhibitor Mechanisms
- Micro and Nano Robotics
- Advanced Materials and Mechanics
- Orthopedic Surgery and Rehabilitation
- Nerve injury and regeneration
- Biochemical and Structural Characterization
- Wireless Power Transfer Systems
- Cardiac Valve Diseases and Treatments
- Traditional and Medicinal Uses of Annonaceae
- Muscle metabolism and nutrition
Rutgers, The State University of New Jersey
2015-2023
University of Pittsburgh
2011-2013
Electroactive hydrogels (EAH) that exhibit large deformation in response to an electric field have received great attention as a potential actuating material for soft robots and artificial muscle. However, their application has been limited due the use of traditional two-dimensional (2D) fabrication methods. Here we present robotic manipulation locomotion with 3D printed EAH microstructures. Through design precise dimensional control enabled by digital light processing (DLP) based micro...
Abstract Advancements in tissue engineering and biomaterial development have the potential to provide a scalable solution problem of large‐volume skeletal muscle defects. Previous research on scaffolds for regeneration has focused strategies increasing conductivity, which improved satellite cell attachment differentiation. However, these usually increase scaffold stiffness, some studies suggest may be detrimental myoblast development. In this study, polymers polypyrrole (PPy)...
Abstract Injuries to peripheral nerves and/or skeletal muscle can cause scar tissue formation and loss of function. The focus this article is the creation a conductive, biocompatible scaffold with appropriate mechanical properties regenerate muscle. Poly(3,4‐ethylenedioxythiophene) (PEDOT) nanoparticles (Np) were electrospun poly(ɛ‐caprolactone) (PCL) form conductive scaffolds. During electrospinning, ribboning, larger fiber diameters, unaligned scaffolds observed increasing PEDOT amounts....
Abstract This paper presents in vitro studies of the sustained release Annona muricata leaf extracts (AME) from hybrid electrospun fibers for breast cancer treatment. Electrospun scaffolds were fabricated crude AME extracts, poly(lactic‐co‐glycolic acid)/gelatin (PLGA/Ge) and pluronic F127. The physicochemical properties extract studied. antiproliferative effects also assessed on (MCF‐7 MDA‐MB‐231) non‐tumorigenic (MCF10A) cell lines. Scanning electron microscope micrographs revealed a...
Abstract During shoulder dislocation, the glenohumeral capsule undergoes non‐recoverable strain, leading to joint instability. Clinicians use physical exams diagnose injury and direct repair procedures; however, they are subjective do not provide quantitative information. Our objectives were to: (1) determine relationship between function following anterior dislocation strain; (2) identify positions at which can be used detect strain in specific regions. Physical simulated three including...
Hydrogels have been used for many applications in tissue engineering and regenerative medicine due to their versatile material properties similarities the native extracellular matrix. Poly (ethylene glycol) diacrylate (PEGDA) is an ionic electroactive polymer (EAP), a that responds electric field with change size or shape while solution, may be development of hydrogels. In this study, we investigated positively charged EAP can bend without need external ions. PEGDA was modified molecule...
Towards the development of new classes subcutaneous muscle prosthesis, this paper presents and discusses results in vitro characterization biocompatible ionic electro-active polymers (iEAPs) under different electrical stimulation scenarios. The is provided via a low-dropout regulator (LDO). functionality electrically stimulated iEAPs evaluated steady-state transient conditions. Electrical characteristics terms conductance, movement changes bending angle during fixed are evaluated. Measured...
Glenohumeral joint stability is maintained by a combination of active and passive soft tissue structures osteoarticular contact. Anatomical that contribute to each these categories include the rotator cuff muscles, glenohumeral capsule, contact between articular surfaces humeral head glenoid scapula, respectively. Dislocation may result in injury one or more stabilizing components requiring other account for deficit. For example, previous research has shown torn supraspinatus tendon results...
The glenohumeral joint is the most frequently dislocated major in body with about 2% of population dislocating their shoulders between ages 18 and 70 [1]. About 80% these shoulder dislocations occur anterior direction, they commonly apprehension position, which characterized by 60° abduction external rotation [2]. common pathology associated dislocation instability due to permanent deformation [3]. Current surgical repair techniques for are inadequate 25% patients still experiencing pain...
In this demonstration, we present a frequency-based system serving as the stimulator for biocompatible ionic electroactive polymers (iEAPs). We will demonstrate that can wirelessly tune both magnitude and polarity of voltage provided by stimulator, changing frequency input signal, to control degree direction movement iEAPs.
Ionic electroactive polymers (iEAPs) respond to electrical stimulation by changing in shape, caused ion displacement inside the polymer. Due similarities between mechanism of action iEAPs and physiology native muscle tissue, have great potentials applications requiring skeletal regeneration. This paper presents a new system-level solution for realization tunable stimulator iEAPs, capable remotely altering degree direction movement iEAPs. Without using digital modulation schemes, proposed...
The anteroinferior glenohumeral capsule (anterior band of the inferior ligament (AB-IGHL), axillary pouch) limits anterior translation, particularly in positions external rotation, and as a result is frequently injured during dislocation. [1,2] A common capsular injury permanent tissue deformation, however, extent effects this are difficult to evaluate deformation cannot be seen using diagnostic imaging. In addition, clinical exams diagnose not reliable [3] poor patient outcome still exists...
The anteroinferior glenohumeral capsule (anterior band of the inferior ligament (AB-IGHL), axillary pouch) limits anterior translation, particularly in positions external rotation. [1, 2] Permanent tissue deformation that occurs as a result dislocation contributes to instability, but, extent and effects this injury are difficult evaluate cannot be seen using diagnostic imaging. Clinical exams used identify appropriate location damage current arthroscopic procedures allow for selective...
The glenohumeral joint is the most frequently dislocated major in body with about 2% of population dislocating their shoulders between ages 18 and 70 [1]. Instability due to permanent deformation capsule commonly associated dislocation [2]. Current surgical repair techniques for shoulder dislocations typically consist plication capsule, or folding tissue over on itself, reduce redundancy restore stability shoulder. Up 25% patients who undergo surgery a still experience pain, instability,...