Chien‐Hung Chen

ORCID: 0000-0003-0115-6288
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About
Contact & Profiles
Research Areas
  • Microwave Imaging and Scattering Analysis
  • EEG and Brain-Computer Interfaces
  • Non-Invasive Vital Sign Monitoring
  • Geophysical Methods and Applications
  • Numerical methods in inverse problems
  • Advanced Statistical Methods and Models
  • Electromagnetic Scattering and Analysis
  • Phonocardiography and Auscultation Techniques
  • High-pressure geophysics and materials
  • Nanowire Synthesis and Applications
  • Advanced Statistical Process Monitoring
  • Optical Imaging and Spectroscopy Techniques
  • Microfluidic and Capillary Electrophoresis Applications
  • Heart Rate Variability and Autonomic Control
  • Non-Destructive Testing Techniques
  • Ultrasonics and Acoustic Wave Propagation
  • Wireless Sensor Networks and IoT
  • Time Series Analysis and Forecasting
  • Nanoplatforms for cancer theranostics
  • Nuclear Materials and Properties
  • Photoreceptor and optogenetics research
  • Healthcare Technology and Patient Monitoring
  • Mineral Processing and Grinding
  • Nuclear Physics and Applications
  • Ion-surface interactions and analysis

Chang Gung University
2020-2023

Taiwan Semiconductor Manufacturing Company (Taiwan)
2023

Stanford University
2017-2022

Institute of Information Science, Academia Sinica
2021

National Health Research Institutes
2018

National Yang Ming Chiao Tung University
2013-2016

Case Western Reserve University
2013

Georgia Institute of Technology
2012

National Applied Research Laboratories
2011

National Chung Hsing University
2010

In this paper, we present a novel charge-free fluorescence-switchable near-infrared (IR) dye based on merocyanine for target specific imaging. contrast to the typical bathochromic shift approach by extending π-conjugation, of our near-IR region is due an unusual S-cis diene conformer. This first example where fluorescent adopts stable conformation. addition mechanism, exhibits properties in response polarity and viscosity. By incorporating protein-specific ligand dye, probes (for SNAP-tag...

10.1021/jacs.8b01159 article EN Journal of the American Chemical Society 2018-03-27

A major issue in thermochronology and U-Th-Pb dating is the effect of radiation damage, created by α-recoils from α-decay events, on diffusion radiogenic elements (e.g., He Pb) host mineral. Up until now, thermal events have been considered as only source energy for recovery radiation-damage. However, irradiation, such α-particle event, can itself induce damage recovery. Quantification radiation-induced caused α-particles during has not possible, process at atomic-scale difficult to observe....

10.1038/s41598-017-14379-9 article EN cc-by Scientific Reports 2017-10-20

Classification of objects is an important area in a variety fields and applications. In the presence full knowledge underlying joint distributions, Bayes analysis yields optimal decision procedure produces error rates. Many different methods are available to make those cases where information distributions not presented. The k nearest neighbor rule (k-NNR) well-known nonparametric procedure. classification rules based on k-NNR have already been proposed applied diverse substantive areas....

10.1109/3477.678652 article EN IEEE Transactions on Systems Man and Cybernetics Part B (Cybernetics) 1998-06-01

This paper reports a two-dimensional time-domain inverse scattering algorithm based upon the finite-difference time domain method (FDTD) for determining shape of perfectly conducting cylinder. FDTD is used to solve electromagnetic wave The problem resolved by an optimization approach and global searching scheme asynchronous particle swarm then employed search parameter space. By properly processing scattered field, some properties can be reconstructed. A set representative numerical results...

10.1117/1.3583998 article EN Journal of Applied Remote Sensing 2011-01-01

The seismocardiography (SCG) is one of the noninvasive diagnostic approaches to detect heart disease such as valvular (VHD) or failure (HF). lack operational guidelines identify SCG feature points in signal waveform made investigation feature-point-labeled template be essential topics researches. For this reason, a new generation method was studied and proposed article. leveraged clustering skill K-means algorithm alignment capability dynamic time warping (DTW) algorithm. merits using are...

10.1109/smc42975.2020.9283120 article EN 2022 IEEE International Conference on Systems, Man, and Cybernetics (SMC) 2020-10-11

Accelerometer-based motion sensing has been extensively applied to fall detection. However, such applications can only detect accidents; therefore, a system that prevent accidents is desirable. Bed falls account for more than half of patient and are preceded by clear warning indicator: the attempting get out bed. This study designed implemented an Internet Things module, namely, Bluetooth low-energy-enabled Sensing In Chip-packaging (BASIC) with tilt-sensing algorithm based on patented...

10.3390/bios11110428 article EN cc-by Biosensors 2021-10-29

We demonstrate a high sensitivity, throughput microfabricated cell sorting device with the integrated piezoelectric actuator and optofluidic waveguide on chip. For automated sorting, field-programmable-gate-array (FPGA) embedded real time control loop system is built. The performed under flow rate (~10 cm/sec), can achieve (> 1 kHz) purity. Moreover, to enhance its Teflon AF coated liquid core (LCW) structure demonstrated. has lower refractive index (n=1.31) than water (n=1.33) forms...

10.1109/iembs.2009.5334976 article EN Annual International Conference of the IEEE Engineering in Medicine and Biology Society 2009-09-01

Accelerometer-based devices have been employed in seismocardiography fiducial point detection with the aid of quasi-synchronous alignment between echocardiography images and seismocardiogram signals. However, signal misalignments observed, due to heartbeat cycle length variation. This paper not only analyzes errors but also proposes mitigate issues by introducing reference signals adynamic time warping (DTW) algorithm. Two diagnostic parameters, ratio pre-ejection period left ventricular...

10.3390/bios12060374 article EN cc-by Biosensors 2022-05-30

To prepare for its new Dolphin Tales exhibit, Georgia Aquarium partnered with Institute of Technology to design the exhibit's guest movement goal enhancing experience while limiting congestion. The result was development and application RealOpt-ABM © simulation decision support system complex modeling optimization. This work advanced knowledge frontier in analytical methods three ways. First, we developed a powerful heuristic algorithm finding good feasible solutions intractable nonlinear...

10.1287/inte.1120.0652 article EN INFORMS Journal on Applied Analytics 2012-10-01

AbstractIn this paper, the shape reconstruction of a perfectly conducting cylinder buried in half-space by measured transverse magnetic scattered field and modified particle swarm optimization (MPSO). Assume that unknown is one scatters incident from another where filed measured. Based on boundary condition field, set nonlinear integral equations derived imaging problem reformulated into an problem. The inverse resolved approach, global searching scheme PSO then employed to search parameter...

10.4103/0377-2063.102307 article EN IETE Journal of Research 2012-01-01

Abstract We propose a parametric robust procedure for comparing several means of dependent populations counts. The validity the proposed method requires no knowledge true underlying joint distributions so long as they have finite second moments. efficacy this novel technique is demonstrated by simulations and analysis data set from Taiwan National Health Insurance Research Database. Our new also compared with popular semi‐parametric generalized estimating equations approach. Copyright © 2007...

10.1002/sim.3032 article EN Statistics in Medicine 2007-08-09

Abstract This article establishes a robust likelihood function about regression parameters for the correlation coefficients modeled in generalized linear model fashion. The validity of proposed requires no knowledge true underlying distributions, so long as they have finite fourth moments. efficacy methodology is shown via simulations. asymptotic variance maximum-likelihood estimate and empirical error probabilities resultant ratio test are specifically exhibited. Keywords: Correlation...

10.1080/02331880601013791 article EN Statistics 2007-02-01

With the rapid development of deep learning, automatic defect detection has been introduced into various manufacturing pipelines. Many studies on inspection focus training an accurate model that can perform well a certain type. However, as process evolves, new types may appear in practice. The trained old will struggle to detect ones. To address this issue, we propose use continual lifelong learning for detection. increasingly learn defects yet keeping learned ones non-forgetting without...

10.1109/indin45523.2021.9557417 article EN 2022 IEEE 20th International Conference on Industrial Informatics (INDIN) 2021-07-21

Surveillance using biomarkers is critical for the early detection, rapid intervention, and reduction in incidence of diseases. In this study, we describe preparation polycrystalline silicon nanowire field-effect transistors (pSNWFETs) that serve as biosensing devices biomarker detection. A protocol chemical biomolecular sensing by pSNWFETs presented. The pSNWFET device was demonstrated to be a promising transducer real-time, label-free, ultra-high-sensitivity applications. source/drain...

10.3791/53660-v article EN Journal of Visualized Experiments 2016-04-21

The development of handheld instruments for point-of-care virus analysis can potentially contribute to medical diagnosis. This study designed, fabricated, and tested a high-resolution multifunction detection system. system comprises microfluidics module, signal processing mechanism module. is capable quickly determining the transistor parameters used in biochemical current range from nano-ampere micro ampere. Additionally, replacement different microfluidic modules provides variety...

10.1109/imtc.2011.5944255 article EN IEEE International Instrumentation and Measurement Technology Conference 2011-05-01

In this paper, an H <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">infin</sub> , state feedback controller is developed for a class of T-S fuzzy systems that not all the states are available measurement. For given system measurement, we design observer to estimate states, and then based on piecewise continuous Lyapunov function guarantee global stability with performance. Finally, by decoupling technique two-stage procedure, overall control...

10.1109/fuzzy.2005.1452481 article EN 2005-07-27

In this paper, the concept of partial multicast protection is explored to decrease blocking probability establishing a connection. The link(s) which carry traffic for multiple destination nodes will be candidates in tree. Only one node not receive data from source when single failed link protected by proposed schemes. But affected can dynamically rejoin its session. way, reduced due saving backup resources. survivability service WDM networks also guaranteed high degree. Extended simulation...

10.1109/icact.2007.358665 article EN International Conference on Advanced Communication Technology 2007-02-01

This paper presents the studies of time domain inverse scattering for a two dimensional inhomogeneous dielectric cylinder buried in slab medium by finite difference (FDTD) method and asynchronous particle swarm optimization (APSO) method. The APSO is applied to reconstruct permittivity two-dimensional cylinder. Numerical result shows that able yield good reconstructed quality.

10.1109/igbsg.2014.6835270 article EN 2014-04-01

An imaging approach to clear detection of two-dimensional geometries is proposed in this paper.The reconstruction multiple dielectric objects retrieved by finite difference time domain (FDTD) method and the asynchronous particle swarm optimization (APSO) determine shape, location permittivity each object.The forward problem solved based on subgrid FDTD using EM pulse illuminate object.In order reduce number unknown parameters for problem, shape function object interpolated terms cubic...

10.5121/csit.2015.51205 article EN 2015-06-13
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