A5018545738- Computational Drug Discovery Methods
- Nonlinear Optical Materials Research
- ZnO doping and properties
- Enzyme Structure and Function
- Crystallography and molecular interactions
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Biochemical and Molecular Research
- Copper-based nanomaterials and applications
- Protein Structure and Dynamics
- Advancements in Battery Materials
- TiO2 Photocatalysis and Solar Cells
- Nanoparticles: synthesis and applications
- Gas Sensing Nanomaterials and Sensors
- Ga2O3 and related materials
- vaccines and immunoinformatics approaches
- Trypanosoma species research and implications
- Magnetic Properties and Synthesis of Ferrites
- HIV/AIDS drug development and treatment
- Agronomic Practices and Intercropping Systems
- Insect symbiosis and bacterial influences
- Advanced biosensing and bioanalysis techniques
- Parasitic Diseases Research and Treatment
- Plant Growth Enhancement Techniques
- Synthesis and biological activity
Karpagam Academy of Higher Education
2023-2025
Tamil Nadu Agricultural University
2023-2024
Anna University Regional Campus, Coimbatore
2023-2024
Anna University, Chennai
2023-2024
Frontier Energy (United States)
2024
Bharath University
2021-2023
Sree Balaji Dental College and Hospital
2021-2023
Southeast University
2019-2023
Alagappa University
2013-2022
Annamalai University
2014-2021
Breast cancer in woman is the most common and 2018 there were around 2 million new cases recorded. The maximum rate of breast reported Belgium followed by Luxembourg. It second general cancer, Lung being first. If tumor located only breast, survival would be 99%. has wide to lymph nodes 85% if had extend distant parts, come down 27%. Mammary gland an important organ mammals which potential function secrete, synthesize deliver milk infants for nourishment, improvement protection. Generally,...
Aluminum-doped zinc oxide (ZnO:Al) thin films were deposited onto glass substrates using spray pyrolysis technique with the substrate temperature of 400 °C. X-ray diffraction analysis indicated that polycrystalline hexagonal wurtzite structure preferentially oriented along (002) direction. Surface morphology obtained by scanning electron microscopy showed grains nanoscale size porous nature for 6 at.% Al. Atomic force observations revealed particles and surface roughness decreased Al-doping....
Type 2 diabetes is one of the biggest health challenges in world and WHO projects it to be 7th leading cause death 2030. It a chronic condition affecting way our body metabolizes sugar. Insulin resistance high risk factor marked by expression Lipoprotein Lipases Peroxisome Proliferator-Activated Receptor that predisposes type diabetes. AMP-dependent protein kinase AMPK signaling pathway central sensor energy status. Deregulation leads inflammation, oxidative stress, deactivation autophagy...
Lymphatic filariasis is a debilitating vector borne parasitic disease that infects human lymphatic system by nematode Brugia malayi. Currently available anti-filarial drugs are effective only on the larval stages of parasite. So far, no for humans to treat filarial infections. In this regard, aspartate semialdehyde dehydrogenase (ASDase) in lysine biosynthetic pathway from Wolbachia endosymbiont malayi represents an attractive therapeutic target development novel agents. present study,...
Although gold nanoparticles based photodynamic therapy (PDT) were reported to improve efficacy and specificity, the impact of surface charge in targeting cancer is still a challenge. Herein, we report nanotriangles (AuNTs) tuned with anionic cationic conjugating triphenylphosphonium (TPP) breast cells 5-aminoleuvinic acid (5-ALA) PDT, vitro. Optimized AuNTs without TPP kill cells. By combining, 5-ALA augmented deliver improved cellular toxicity as revealed by MTT, fluorescent probes flow...
Introduction: The marine habitat is a plentiful source of diverse, active compounds that are extensively utilised for their medicinal properties. Pharmaceutical trends have currently changed towards utilising diverse range goods derived from the environment. Method: This study aimed to examine inhibitory effects bioactive chemicals algae and bacteria. identification these was carried out through process Gas Chromatography-Mass Spectrometry (GC-MS) profiling. Subsequently, were subjected...
ABSTRACT Lymphatic filariasis (LF) is a mosquito‐borne disease caused by parasitic nematodes Brugia malayi, timori , and Wuchereria bancrofti . The drugs available are effective in several cases, the absence of vaccination crucial factor hindering elimination LF. UDP‐ N ‐acetylmuramoyl‐L‐alanyl‐D‐glutamate‐2,6‐diaminopimelate ligase (MurE) plays an important role peptidoglycan biosynthesis Wolbachia endosymbiont B. malayi which reported to be vital drug target for bacterial endosymbiotic...
Abstract Objectives Cancer remains a significant global health challenge, with prostate, breast, and ovarian cancers ranking among the leading causes of morbidity mortality. Natural products, particularly those derived from medicinal plants, have gained attention for their potential in alternative cancer therapies. The main objective study was an isolation characterization Jerantinine A, bioactive alkaloid Tabernaemontana coronaria , its interactions key protein targets involved progression....
Prostate cancer is the second most dangerous type worldwide. While various treatment options are present i.e. agonists and antagonists, their utilization leads to adverse effects due this resistance developing, ultimately outcome remission. So, overcome issue, we have undertaken an in-silico investigation identify promising unique flavonoid candidates for combating prostate cancer. Using GOLD software, study assessed effectiveness of 560 natural secondary polyphenols against CDKN2. Protein...