A5038861297- RNA Interference and Gene Delivery
- Extracellular vesicles in disease
- Immune Response and Inflammation
- Immunotherapy and Immune Responses
- Ocular Infections and Treatments
- Nanopore and Nanochannel Transport Studies
- Catalysts for Methane Reforming
- Mycobacterium research and diagnosis
- MicroRNA in disease regulation
- Immune Cell Function and Interaction
- Ocular Surface and Contact Lens
- Catalytic Processes in Materials Science
- Catalysis and Oxidation Reactions
- Intraocular Surgery and Lenses
- Bacteriophages and microbial interactions
- Dendrimers and Hyperbranched Polymers
University of Pittsburgh
2022
Washington State University
2016-2018
Exosomes play a significant role in cancer progression and are potentially useful biomarkers for noninvasive diagnostics therapeutic treatments. Although exosomes difficult to study because of their small, inconsistent sizes challenging purification processes, new micro- nanotechnologies have been recently developed that seek overcome these limitations. In this review, we examine compare isolation detection techniques various types extracellular vesicles (EVs) including exosomes, which <200...
We evaluated the potential of a nanoparticle (NP) delivery system to improve methods candidate peptide‐based vaccines for Paratuberculosis in cattle. Peptides derived from Mycobacterium avium subsp. paratuberculosis (Map), and pro‐inflammatory monophosphoryl lipid A (MPLA) were incorporated polymeric NPs based on poly (d,l‐lactide‐co‐glycolide) (PLGA). The PLGA/MPLA carriers incubated with macrophages examine their effects survival function. NPs, without Map antigens, are efficiently...
Poly (lactic-co-glycolic acid) nanoparticles (PLGA NPs) have been considerably studied as a promising biodegradable delivery system to induce effective immune responses and improve stability, safety, cost effectiveness of vaccines. The study aimed at evaluating early inflammatory effects cellular safety PLGA NPs, co-encapsulating ovalbumin (PLGA/OVA NPs), model antigen the adjuvant monophosphoryl lipid A (PLGA/MPLA an adjuvant, on primary canine macrophages. NPs constructs were prepared...
Purpose: Intravitreal injection has become a popular treatment for various retina disorders and dramatically increased over the past few years. In traditional preintravitreal injection, preparation steps are time consuming practitioners who perform significant number of injections per day. Besides, lidocaine gel (L-Gel) shows potential absorption barrier on antibacterial effect povidone iodine (PI). Methods: this study, we describe L/PI system as an alternative approach to address these...