- Cardiac Imaging and Diagnostics
- Pain Management and Treatment
- Cardiac Valve Diseases and Treatments
- Cardiac pacing and defibrillation studies
- Coronary Interventions and Diagnostics
- Acute Myocardial Infarction Research
- Infective Endocarditis Diagnosis and Management
- Cardiac, Anesthesia and Surgical Outcomes
- Aortic Disease and Treatment Approaches
- COVID-19 Clinical Research Studies
- Cardiac Structural Anomalies and Repair
- Advanced MRI Techniques and Applications
- Heart rate and cardiovascular health
- Cardiac Arrhythmias and Treatments
- Fish Biology and Ecology Studies
- Pain Mechanisms and Treatments
- Mechanical Circulatory Support Devices
- Aortic aneurysm repair treatments
- Infectious Aortic and Vascular Conditions
- Pericarditis and Cardiac Tamponade
- Identification and Quantification in Food
- Cardiac and Coronary Surgery Techniques
- Diabetes and associated disorders
- Musculoskeletal pain and rehabilitation
- COVID-19 and healthcare impacts
Maria Cecilia Hospital
2020-2022
Istituti di Ricovero e Cura a Carattere Scientifico
2017-2022
Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele
2017-2022
Vita-Salute San Raffaele University
2017-2022
Humanitas University
2022
Training Programs in Epidemiology and Public Health Interventions Network
2018
San Raffaele University of Rome
2018
Abstract Objectives To evaluate the impact of coronary sinus (CS) Reducer implantation upon left ventricular (LV) function. Background CS is associated with symptomatic relief in patients refractory angina. The effects device function remains unknown. Methods Prior to and at 4‐months, resting volumes were measured using cardiac magnetic resonance (CMR). Stress CMR was performed extract quantitative indices myocardial perfusion (myocardial reserve index‐MPRI). Results Nineteen (18 males, 66.0...
The coronary sinus Reducer is a percutaneous device proven to improve angina symptoms in refractory (RA). We evaluated its potential cost-effectiveness and impact on the healthcare resource use. Angina-related usage quality-of-life data were collected for 215 consecutive RA patients undergoing implantation Belgium, Netherlands, Italy. Costs assessed from each country's system perspective. Data date of diagnosis [Standard-of-Care (SoC)-period] follow-up (Reducer-period) compared: during...
Abstract Background Coronary sinus (CS) narrowing by reducer implantation has emerged as a safe and effective therapy for patients suffering from refractory angina. However, data regarding the clinical benefit of this treatment over time is lacking. Methods Patients undergoing successful were enrolled prospectively to registries at three medical centers. Those with more than 2‐years follow‐up included in present analysis. Peri‐procedural data, adverse events, current evaluation angina...
Clinical efficacy of coronary sinus reducer (CSR) in refractory angina (RA) patients with ischemia due to the chronic total occlusion (CTO) right artery (RCA) remains unknown.To evaluate CSR implantation RA CTO RCA and compare them recipients left (LCA) ischemia.Consecutive from 2 centers were prospectively included compared LCA ischemia. All underwent evaluation severity quality life (QoL) at baseline after 12 months. In a subgroup patients, stress cardiac magnetic resonance (CMR) imaging...
Background Coronary access after transcatheter aortic valve implantation (TAVI) with supra-annular self-expandable valves may be challenging or un-feasible. There is little data concerning coronary following valve-in-valve (ViV-TAVI) for degenerated surgical bioprosthesis. Aims To evaluate the feasibility and challenge of ViV-TAVI ACURATE neo valve. Materials methods Sixteen patients underwent Post-procedural computed tomography (CT) was used to create 3D-printed life-sized patient-specific...
Valve-in-valve transcatheter aortic valve replacement (ViV-TAVR) is an emerging alternative to re-do surgery. However, the challenge of coronary access (CA) following ViV-TAVR a potential limitation as TAVR expands younger lower-risk populations.Using post-implantation computed tomography (CT) scans evaluate geometrical relationship between ostia and frame in patients undergoing with ACURATE neo valve.Post-implant CT 18 out 20 consecutive treated were analyzed. Coronary location relation...
Refractory angina affects an increasing proportion of the population with advanced coronary artery disease and microvascular dysfunction. Limited effective pharmacological interventional therapies exist for this patient cohort. The sinus (CS) reducer, recently recommended in 2019 guidelines European Society Cardiology management chronic refractory angina, is a balloon-expandable, stainless-steel device designed implantation CS. It acts by CS pressure, thereby redistributing blood to ischemic...
Coronary sinus (CS) reducer implantation is associated with symptomatic relief of patients refractory angina. However, 15% to 30% the do not respond this treatment. Aim if study was evaluate effect CS size in effectiveness device.Prior device and at 4-month resting ventricular function assessed by stress cardiac magnetic resonance. Ischemia myocardial perfusion reserve index (MPRI).Fifteen (66 ± 10 years) underwent successful Reducer implantation, improvements angina class exercise...