Alessandra Scoccia
A5054725035- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Acute Myocardial Infarction Research
- COVID-19 and healthcare impacts
- Cardiac Valve Diseases and Treatments
- Cardiac Arrest and Resuscitation
- COVID-19 Clinical Research Studies
- Cardiovascular Function and Risk Factors
- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular Disease and Adiposity
- Heart Failure Treatment and Management
- Antiplatelet Therapy and Cardiovascular Diseases
- Diabetes Treatment and Management
- Aortic aneurysm repair treatments
- Cardiovascular and Diving-Related Complications
- Venous Thromboembolism Diagnosis and Management
- Cardiac Arrhythmias and Treatments
- Healthcare cost, quality, practices
- Cardiac pacing and defibrillation studies
- Mechanical Circulatory Support Devices
- Vascular Procedures and Complications
- Peripheral Artery Disease Management
- Non-Invasive Vital Sign Monitoring
- Atrial Fibrillation Management and Outcomes
- Pericarditis and Cardiac Tamponade
Ospedale Sant'Anna
2020-2025
Erasmus MC
2022-2025
Sapienza University of Rome
2024
Arcispedale Sant'Anna
2019-2023
Erasmus University Rotterdam
2022-2023
Maria Cecilia Hospital
2021-2022
Azienda Ospedaliera S.Giuseppe Moscati
2021
Centro Cardiologico Monzino
2018-2021
University of Ferrara
2021
Cardiovascular Institute of the South
2021
ABSTRACT Background Fractional flow reserve (FFR) following percutaneous coronary intervention (PCI) can be used to evaluate procedural success and guide stent optimization. Several studies have demonstrated that lower FFR after implantation is associated with increased adverse event rates up 2 years. However, the impact of post‐PCI on very long‐term clinical outcome remains unknown. Methods The SEARCH study a single‐center, prospective, observational including consecutive patients...
The initial data of the International Study on Acute Coronary Syndromes - ST Elevation Myocardial Infarction COVID-19 showed in Europe a remarkable reduction primary percutaneous coronary intervention procedures and higher in-hospital mortality during phase pandemic as compared with prepandemic period. aim current study was to provide final results registry, subsequently extended outside larger inclusion period (up June 2020) longer follow-up 30 days).This is retrospective multicentre...
Abstract Background It has been suggested the COVID pandemic may have indirectly affected treatment and outcome of STEMI patients, by avoidance or significant delays in contacting emergency system. No data reported on impact diabetes that was therefore aim current subanalysis conducted patients included International Study Acute Coronary Syndromes–ST Elevation Myocardial Infarction (ISACS-STEMI) COVID-19. Methods The ISACS-STEMI COVID-19 is a retrospective registry performed European centers...
Abstract Purpose Wire-based coronary physiology pullback performed before percutaneous intervention (PCI) discriminates artery disease (CAD) distribution and extent, is able to predict functional PCI result. No research investigated if quantitative flow ratio (QFR)–based assessment provide similar information. Methods In 111 patients (120 vessels) treated with PCI, QFR was measured both after PCI. Pre-PCI trace used discriminate patterns of CAD (focal, serial lesions, diffuse disease,...
Resistant hypertension (RHT) is characterized by persistently high blood pressure (BP) levels above the widely recommended therapeutic targets of less than 140/90 mmHg office BP, despite life-style measures and optimal medical therapies, including at least three antihypertensive drug classes maximum tolerated dose (one should be a diuretic). This condition strongly related to hypertension-mediated organ damage and, mostly, risk hospitalization due emergencies or acute cardiovascular events....
Ticagrelor is a powerful P2Y12 inhibitor with pleiotropic effects in the cardiovascular system. Consistently, we have reported that patients stable coronary artery disease (CAD) and concomitant chronic obstructive pulmonary (COPD) who underwent percutaneous intervention (PCI), 1-month treatment ticagrelor was superior improving biological markers of endothelial function, compared clopidogrel. The objective this study to investigate mechanisms underlying these beneficial by conducting...
Abstract Recent clinical and demographical studies on COVID-19 patients have demonstrated that men experience worse outcomes than women. However, in most cases, the data were not stratified according to gender, limiting understanding of real impact gender outcomes. This study aimed evaluate disaggregated in-hospital explore possible interactions between cardiovascular calcifications. Data was derived from sCORE-COVID-19 registry, an Italian multicentre registry enrolled who had undergone a...
Vessel Fractional Flow Reserve (vFFR) as assessed by three-dimensional quantitative coronary angiography has high correlation with pressure wire-based fractional flow reserve in both a pre- and post-PCI setting. The present study aims to assess the prognostic value of vFFR on incidence target vessel failure (TVF), composite endpoint cardiac death, myocardial infarction revascularization (TVR) at 5-year follow up.Post-PCI was calculated after routine PCI total 748 patients (832 vessels)...
Background: Several scores have been developed to facilitate risk stratification and early discharge following primary angioplasty, particularly the Zwolle Risk Score (ZRS). However, validation in large-sized studies is still lacking. Therefore, aim of current study was validate use ZRS a contemporary global population, including patients who were treated during SARS-CoV-2 pandemic enrolled large intercontinental observational study. Methods: The ISACS-STEMI COVID-19 large-scale...
Abstract Objectives To investigate the correlation between quantitative flow ratio (QFR), Pd/Pa, diastolic hyperemia‐free (DFR) and fractional reserve (FFR, gold standard) in non‐culprit lesion (NCL) of patients with non ST‐segment elevation myocardial infarction (NSTEMI). Background The non‐hyperemic pressure (NHPR) angiography‐based indexes have been developed to overcome limitation use FFR. Methods Between January December 2019, 184 NCL from 116 NSTEMI underwent physiologic assessment...
Physiological assessment of intermediate coronary lesions to guide revascularization is currently recommended by international guidelines. Vessel fractional flow reserve (vFFR) has emerged as a new approach derive (FFR) from 3D-quantitative angiography (3D-QCA) without the need for hyperemic agents or pressure wires. The FAST III an investigator-initiated, open label, multicenter randomized trial comparing vFFR guided versus FFR in approximately 2228 patients with (defined 30%-80% stenosis...
Dedicated prospective studies investigating high-definition intravascular ultrasound (HD-IVUS)-guided primary percutaneous coronary intervention (PCI) are lacking. The aim of this study was to qualify and quantify culprit lesion plaque characteristics thrombus using HD-IVUS in patients presenting with ST-segment elevation myocardial infarction (STEMI).The SPECTRUM is a prospective, single-center, observational cohort the impact HD-IVUS-guided PCI 200 STEMI (NCT05007535). first 100 de novo...
Abstract Background Severe coronary artery calcification is associated with stent underexpansion and subsequent failure. Aims We aimed to identify optical coherence tomography (OCT)‐derived predictors of absolute (minimal area [MSA]) relative expansion in calcified lesions. Methods This retrospective cohort study included patients who underwent percutaneous intervention (PCI) OCT assessment before after implantation between May 2008 April 2022. Pre‐PCI was used assess calcium burden post‐PCI...
Introduction Intravascular ultrasound (IVUS) improves clinical outcome in patients undergoing percutaneous coronary intervention (PCI) but dedicated prospective studies assessing the safety and efficacy of IVUS guidance during primary PCI are lacking. Methods analysis The SPECTRUM study is a investigator-initiated single-centre single-arm observational cohort aiming to enrol 200 presenting with ST-segment elevation myocardial infarct IVUS-guided PCI. will be performed at baseline,...