Enrico Fabris
- Coronary Interventions and Diagnostics
- Acute Myocardial Infarction Research
- Cardiac Imaging and Diagnostics
- Cardiac Valve Diseases and Treatments
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiovascular Function and Risk Factors
- Heart Failure Treatment and Management
- Cardiac Structural Anomalies and Repair
- Cardiac Arrest and Resuscitation
- Cardiac pacing and defibrillation studies
- Cardiomyopathy and Myosin Studies
- Viral Infections and Immunology Research
- COVID-19 and healthcare impacts
- Atrial Fibrillation Management and Outcomes
- Peripheral Artery Disease Management
- Cardiovascular Effects of Exercise
- Cerebrovascular and Carotid Artery Diseases
- Mechanical Circulatory Support Devices
- Cardiac Arrhythmias and Treatments
- Cardiac tumors and thrombi
- Infective Endocarditis Diagnosis and Management
- Pericarditis and Cardiac Tamponade
- Venous Thromboembolism Diagnosis and Management
- Cardiac electrophysiology and arrhythmias
- Eosinophilic Disorders and Syndromes
Azienda Sanitaria Universitaria Integrata di Trieste
2017-2025
University of Trieste
2016-2025
Azienda Ospedaliero Universitaria Ospedali Riuniti
2015-2024
Isala
2016-2024
ERN GUARD-Heart
2024
Ospedale di Cattinara
2014-2024
Radboud University Medical Center
2024
Leiden University Medical Center
2024
Radboud University Nijmegen
2024
University Medical Center Utrecht
2024
Abstract Aims The aim of this study was to understand the impact optical coherence tomography (OCT)-detected thin-cap fibroatheroma (TCFA) on clinical outcomes diabetes mellitus (DM) patients with fractional flow reserve (FFR)-negative lesions. Methods and results COMBINE OCT-FFR a prospective, double-blind, international, natural history study. After FFR assessment, revascularization FFR-positive lesions, ≥1 FFR-negative lesions (target lesions) were classified in two groups based presence...
Abstract Objective To show that limiting dual antiplatelet therapy (DAPT) to six months in patients with event-free ST-elevation myocardial infarction (STEMI) results a non-inferior clinical outcome versus DAPT for 12 months. Design Prospective, randomised, multicentre, non-inferiority trial. Setting Patients STEMI treated primary percutaneous coronary intervention (PCI) and second generation zotarolimus-eluting stent. Participants aged 18 85 underwent PCI the implantation of drug-eluting...
BackgroundOne third of patients undergoing transcatheter aortic-valve implantation (TAVI) have an indication for oral anticoagulation owing to concomitant diseases. Interruption during TAVI may decrease the risk bleeding, whereas continuation thromboembolism.MethodsWe conducted international, open-label, randomized, noninferiority trial involving who were receiving anticoagulants and planning undergo TAVI. Patients randomly assigned in a 1:1 ratio periprocedural or interruption...
Background: Cardiogenic shock (CS) is the most frequent cause of in-hospital mortality after ST-elevation myocardial infarction (STEMI). Data about CS in very elderly (age ≥ 85 years) STEMI patients are scarce. We sought to assess prognostic factors and short- mid-term impact this population. Methods: Consecutive undergoing invasive treatment were included a retrospective multicenter registry. Results: Among 608 patients, 72 (11.8%) fulfilled experienced CS. Peripheral artery disease (PAD)...
Aims This study reports on the concerns about myocarditis and pericarditis following COVID-19 vaccination that have been raised worldwide. However, heterogeneous diagnostic criteria for postvaccination inflammatory heart diseases may result in overestimating incidence rates. The aim of this multicentre Italian registry is to evaluate impact vaccines population. Methods Consecutive patients admitted hospitals endomyocardial and/or cardiac magnetic resonance proven acute same period (1 June–31...
To evaluate the long-term clinical impact of application cardiac rehabilitation (CR) early after discharge in a real-world population.We analysed 5-year incidence cardiovascular mortality and hospitalization for causes two populations, attenders vs. non-attenders to an ambulatory CR program which were consecutively discharged from tertiary hospitals, ST-elevation myocardial infarction, non-ST-elevation coronary artery bypass graft, or planned percutaneous intervention. A primary analysis...
BACKGROUND: Despite fractional flow reserve (FFR)–guided deferral of revascularization, recurrent events in patients with diabetes or after myocardial infarction remain common. This study aimed to assess the association between FFR-negative but high-risk nonculprit lesions and clinical outcomes. METHODS: is a patient-level pooled analysis prospective natural-history COMBINE (OCT-FFR) (Optical Coherence Tomography Morphologic Fractional Flow Reserve Assessment Diabetes Mellitus Patients)...
The initial data of the International Study on Acute Coronary Syndromes - ST Elevation Myocardial Infarction COVID-19 showed in Europe a remarkable reduction primary percutaneous coronary intervention procedures and higher in-hospital mortality during phase pandemic as compared with prepandemic period. aim current study was to provide final results registry, subsequently extended outside larger inclusion period (up June 2020) longer follow-up 30 days).This is retrospective multicentre...
Autopsy studies have established that thin-cap fibroatheromas (TCFAs) are the most frequent cause of fatal coronary events. In living patients, optical coherence tomography (OCT) has sufficient resolution to accurately differentiate TCFA from thick-cap fibroatheroma (ThCFA) and not lipid rich plaque (non-LRP). However, impact OCT-detected phenotype nonischemic lesions on future adverse events remains unknown. Therefore, we studied natural history TCFA, ThCFA, non-LRP in patients enrolled...
Thin-cap fibroatheroma (TCFA) lesions are associated with a high risk of future major adverse cardiovascular events. However, the impact other optical coherence tomography-detected vulnerability features (OCT-VFs) and their interplay TCFA in predicting events remains unknown.
Fractional flow reserve (FFR) is a widely used tool for the identification of ischaemia-generating stenoses and to guide decisions on coronary revascularisation. However, safety FFR-based in high-risk subsets, such as patients with Diabetes Mellitus (DM) or vulnerable presenting thin-cap fibro-atheroma (TCFA), unknown. This study will examine impact optical coherence tomography (OCT) plaque morphological assessment TCFA, combination FFR better predict clinical outcomes DM patients. COMBINE...
Deferred revascularisation based upon fractional flow reserve (FFR >0.80) is associated with a low incidence of target lesion failure (TLF). Whether deferred also as safe in diabetes mellitus (DM) patients unknown.All DM and the next consecutive Non-DM who underwent FFR-assessment between 1/01/2010 31/12/2013 were included, followed until 1/07/2015. Patients lesions FFR >0.80 analysed according to presence vs. absence DM, while index FFR-assessed or other excluded. The primary endpoint was...