A5005080790- Acute Myocardial Infarction Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac Arrest and Resuscitation
- Mechanical Circulatory Support Devices
- Cardiac Imaging and Diagnostics
- Coronary Interventions and Diagnostics
- Cardiac Structural Anomalies and Repair
- Cardiac Valve Diseases and Treatments
- Venous Thromboembolism Diagnosis and Management
- Atrial Fibrillation Management and Outcomes
- Cardiac, Anesthesia and Surgical Outcomes
- Heart Failure Treatment and Management
- Emergency and Acute Care Studies
- Diversity and Career in Medicine
- Cardiovascular Function and Risk Factors
- Congenital Heart Disease Studies
- Inflammatory mediators and NSAID effects
- Healthcare Systems and Practices
- Drug-Induced Adverse Reactions
- Cardiovascular Issues in Pregnancy
- Healthcare Policy and Management
- Cardiac Arrhythmias and Treatments
- Lipoproteins and Cardiovascular Health
- Cardiac Health and Mental Health
- Coronary Artery Anomalies
Sorbonne Université
2023-2025
Pitié-Salpêtrière Hospital
2023-2025
Assistance Publique – Hôpitaux de Paris
2013-2025
Inserm
2012-2024
Université Toulouse III - Paul Sabatier
2024
Hôpital Charles-Foix
2023
Université Paris 1 Panthéon-Sorbonne
2023
Hôpital Lariboisière
2011-2021
Université Paris Cité
2012-2021
Shaare Zedek Medical Center
1996-2021
Background— Acute coronary occlusion is the leading cause of cardiac arrest. Because limited data, indications and timing angiography angioplasty in patients with out-of-hospital arrest are controversial. Using data from Parisian Region Out hospital Cardiac ArresT prospective registry, we performed an analysis to assess effect invasive strategy on survival. Methods Results— Between January 2003 December 2008, 714 were referred a tertiary center Paris, France. In 435 no obvious extracardiac...
This consensus document, a summary of the views an expert panel organized by European Association Percutaneous Cardiovascular Interventions (EAPCI), appraises importance ischaemia with non-obstructive coronary arteries (INOCA). Angina pectoris affects approximately 112 million people globally. Up to 70% patients undergoing invasive angiography do not have obstructive artery disease, more common in women than men, and large proportion INOCA as cause their symptoms. present wide spectrum...
This consensus document, a summary of the views an expert panel organized by European Association Percutaneous Cardiovascular Interventions (EAPCI), appraises importance ischaemia with non-obstructive coronary arteries (INOCA). Angina pectoris affects approximately 112 million people globally. Up to 70% patients undergoing invasive angiography do not have obstructive artery disease, more common in women than men, and large proportion INOCA as cause their symptoms. present wide spectrum...
Recent guidelines recommend the immediate performance of a coronary angiography when an acute myocardial infarction is suspected as cause out-of-hospital cardiac arrest. However, prehospital factors such postresuscitation electrocardiogram pattern or clinical features are poorly sensitive in this setting. We searched to evaluate if early measurement troponin I can help detect recent occlusion arrest.Retrospective analysis prospective electronic registry database.University arrest...
The initial data of the International Study on Acute Coronary Syndromes - ST Elevation Myocardial Infarction COVID-19 showed in Europe a remarkable reduction primary percutaneous coronary intervention procedures and higher in-hospital mortality during phase pandemic as compared with prepandemic period. aim current study was to provide final results registry, subsequently extended outside larger inclusion period (up June 2020) longer follow-up 30 days).This is retrospective multicentre...
In the setting of ST-elevation myocardial infarction (STEMI), epicardial vasoconstriction and thrombus load may lead to stent undersizing malapposition after primary percutaneous coronary intervention (PPCI), which can both be responsible for thrombosis or restenosis. Aggressive deployment can, on other hand, cause distal embolisation no-reflow phenomenon. The purpose our study was evaluate safety feasibility a novel self-expanding by assessing clinical, angiographic intravascular outcomes...
Abstract— Treatment of hypertensive patients with β-blockers reduces heart rate and decreases central blood pressure less than other antihypertensive drugs, implying that reducing without altering brachial could increase pressure, explaining the increased cardiovascular risk reported β-blocker. We describe a randomized, double-blind study to explore whether reduction I f inhibitor ivabradine had an impact on pressure. included 12 normotensive stable coronary artery disease, ≥70 bpm (sinus...
On-admission coronary angiogram (CA) with angioplasty (percutaneous intervention, PCI) may improve survival in patients resuscitated from out-of-hospital cardiac arrest (OHCA), but long-term data are scarce. We assessed OHCA managed on-admission CA and PCI if indicated compared rates with/without acute syndrome (ACS).Retrospective single-centre study including aged ≥18 years an without noncardiac cause, sustained return of spontaneous circulation, undergoing indicated. ACS was diagnosed...
Cardiogenic shock (CS) in patients with left ventricular hypertrophy (LVH) due to hypertrophic cardiomyopathy (HCM) or hypertensive heart disease, is underreported the literature. This study aimed delineate characteristics, management strategies and outcomes of experiencing CS preexisting LVH HCM. FRENSHOCK a prospective multicenter registry including 772 unselected from 49 centers. Baseline 1-year were analyzed according occurrence on LVH. Within included, occur 34 (4.4%, 1.4% HCM)....
An appropriate diagnostic process is crucial for managing patients with acute heart failure (AHF) in emergency department (ED). Our study aims to describe the characteristics and therapeutic management of admitted ED dyspnea suspected have AHF, their in-hospital pathway care outcome. Consecutive 26 French be consequence prior hospital test, were prospectively included at time admission DeFSSICA Survey. Clinical recorded by physicians. At discharge from ED, categorized as AHF or non-AHF based...
Cell transplantation and associated neovascularization in vivo may be beneficial ischemic disease. We hypothesized that transplanted mesothelial cells (MCs) could improve the post-myocardial infarct scar rats.Myocardial infarction was created by left coronary artery ligation Lewis rats. After 3 weeks, surviving rats with ventricular (LV) ejection fraction (EF) <50% were randomized into 2 groups which received, via injection scar, either syngeneic rat peritoneal MCs (transplanted group) or...
Fucoidan, a sulfated polysaccharide extracted from brown seaweed, is candidate for the treatment of ischemic diseases. The aim this study was to measure therapeutic potential fucoidan in rat model myocardial ischemia–reperfusion injury. Forty rats were submitted injury by transient occlusion left coronary artery. Rats then randomized into 2 groups: (5 mg/kg, intramuscularly; n = 20) or control (saline administered 1 hour before and daily thereafter month. At month, plasma levels stromal...
Objectives Cardiorenal syndrome (CRS) is the combination of acute heart failure (AHF) and renal dysfunction (creatinine clearance (CrCl) ≤60 mL/min). Real-life data were used to compare management outcome AHF with without dysfunction. Design Prospective, multicentre. Setting Twenty-six academic, community regional hospitals in France. Participants 507 patients assessed two groups according function: group 1 (patients CRS (CrCl mL/min): n=335) 2 normal function >60 n=172). Results...
Repeat open-heart operations are becoming more frequent with a patient population at higher risk. Sternal re-entry poses the risk of possible damage to vital structures. These include laceration myocardium, especially right ventricle, tearing patent grafts and internal mammary in particular, or dislodgement emboli from vein grafts. To minimize associated sternal re-entry, we adopted method establishing femoral artery-femoral cardiopulmonary bypass (CPB) order achieve cardiac decompression...