A5075405373- Mechanical Circulatory Support Devices
- Cardiac Structural Anomalies and Repair
- Cardiac Arrest and Resuscitation
- Optical Imaging and Spectroscopy Techniques
- Cardiac Valve Diseases and Treatments
- Photoacoustic and Ultrasonic Imaging
- Cardiac, Anesthesia and Surgical Outcomes
- Healthcare Systems and Practices
- Cardiomyopathy and Myosin Studies
- Infrared Thermography in Medicine
- Health, Medicine and Society
- Ultrasound and Hyperthermia Applications
- Organ Transplantation Techniques and Outcomes
- Transplantation: Methods and Outcomes
Centre National de la Recherche Scientifique
2021-2025
Inserm
2020-2025
Université de Montpellier
2021-2025
Hôpital Arnaud de Villeneuve
2021-2025
Centre Hospitalier Universitaire de Montpellier
2022-2024
Physiologie et Médecine Expérimentale du Coeur et des Muscles
2020-2021
Clinique du Millénaire
2017
Centre Hospitalier de Béziers
2015
Cardiogenic shock (CS) is a sudden low-cardiac-output state resulting in life-threatening hypoperfusion, complicating 3–13% of acute myocardial infarctions (AMI).1 Despite urgent revascularization and advanced mechanical circulatory support (aMCS) devices (extracorporeal life [ECLS], microaxial flow pump [mFP]), AMI-CS mortality remains unacceptably high approaching 45–60% at 1 year. While the latest guidelines for AMI management1 suggest that aMCS (whatever device used) may be considered...
Cardiogenic shock (CS) in patients with left ventricular hypertrophy (LVH) due to hypertrophic cardiomyopathy (HCM) or hypertensive heart disease, is underreported the literature. This study aimed delineate characteristics, management strategies and outcomes of experiencing CS preexisting LVH HCM. FRENSHOCK a prospective multicenter registry including 772 unselected from 49 centers. Baseline 1-year were analyzed according occurrence on LVH. Within included, occur 34 (4.4%, 1.4% HCM)....
Acute myocardial infarction-related cardiogenic shock (AMICS) is associated with persistent high early mortality rates ranging from 40% to 60%.1-6 Despite advancements in AMICS knowledge, few positive studies have impacted patient outcomes. Indeed, landmark trials such as SHOCK3 and CULPRIT-SHOCK4 provided valuable insights into (CS) management, but did not highlight the potential benefit of temporary mechanical circulatory support (tMCS). Recently, four randomized controlled (RCTs)...
Aims: Microvascular alterations occurring after myocardial infarction (MI) may represent a risk factor for multi-organ failure. Here we used in vivo photoacoustic (PA) imaging to track and define the changes vascular oxygen saturation (sO 2 ) over time experimental MI multiple peripheral organs brain. Methods Results: Experimental was obtained BALB/c mice by permanent ligation of left anterior descending artery. PA (Vevo LAZR-X) allowed tracking mouse-specific sO kinetics cardiac ventricular...
Over the past decade, extracorporeal life support (ECLS) has gained increasing utilization in management of refractory cardiogenic shock (CS) with a class IIaC recommendation according to latest European and US guidelines.1 However, recent randomized controlled trials (RCTs) meta-analyses can be considered inconclusive demonstrating benefit ECLS compared optimal medical treatment patients acute myocardial infarction complicated by CS. Various factors may explain these neutral results but...
Abstract Background: Encouraging results in several series of patients on refractory cardiogenic shock (CS) led to the consideration including temporary mechanical circulatory support (TMCS) guidelines for CS management. Benefit survival might be improved when TMCS devices are initiated early. This study assessed early real-world condition a cardiac assistance regional network. Methods: We examined clinical features and outcomes treated with TMCS, using data from prospective cohort admitted...
Abstract Background The field of temporary mechanical circulatory support (TMCS) has advanced in last decade justifying that TMCS is increasingly used for treatment refractory cardiogenic shock (CS). Nevertheless, the efficacy (extracorporeal life (ECLS) and Impella) CS remains controversial due to lack high-quality evidence. aim this prospective multicenter observational study simulating a randomized trial was assess impact on hospital mortality patients with CS. Methods This...