Raúl Moreno
A5101457385- Cardiac Valve Diseases and Treatments
- Coronary Interventions and Diagnostics
- Acute Myocardial Infarction Research
- Infective Endocarditis Diagnosis and Management
- Aortic Disease and Treatment Approaches
- Atrial Fibrillation Management and Outcomes
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac Imaging and Diagnostics
- Cardiac Arrest and Resuscitation
- Coronary Artery Anomalies
- COVID-19 and healthcare impacts
- Venous Thromboembolism Diagnosis and Management
- Mechanical Circulatory Support Devices
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Arrhythmias and Treatments
- Congenital Heart Disease Studies
- Health Systems, Economic Evaluations, Quality of Life
- Kawasaki Disease and Coronary Complications
- Immunodeficiency and Autoimmune Disorders
- Cardiac pacing and defibrillation studies
- Heart Failure Treatment and Management
- Pulmonary Hypertension Research and Treatments
- Cardiac electrophysiology and arrhythmias
- Testicular diseases and treatments
- Medical Coding and Health Information
Hospital Universitario La Paz
2016-2025
Hamilton Health Sciences
2024
Universidad Autónoma de Madrid
2021-2024
Radboud University Medical Center
2024
Christ Hospital
2024
Health Net
2024
Radboud University Nijmegen
2024
Population Health Research Institute
2024
Sorbonne Université
2024
St Mary's Hospital
2024
BackgroundInflammation is associated with adverse cardiovascular events. Data from recent trials suggest that colchicine reduces the risk of events.MethodsIn this multicenter trial a 2-by-2 factorial design, we randomly assigned patients who had myocardial infarction to receive either or placebo and spironolactone placebo. The results are reported here. primary efficacy outcome was composite death causes, recurrent infarction, stroke, unplanned ischemia-driven coronary revascularization,...
The role of direct oral anticoagulants as compared with vitamin K antagonists for atrial fibrillation after successful transcatheter aortic-valve replacement (TAVR) has not been well studied.We conducted a multicenter, prospective, randomized, open-label, adjudicator-masked trial comparing edoxaban in patients prevalent or incident the indication anticoagulation TAVR. primary efficacy outcome was composite adverse events consisting death from any cause, myocardial infarction, ischemic...
Patients experiencing myocardial infarction (MI) remain at high risk of future major adverse cardiovascular events (MACE). While low-dose colchicine and spironolactone have been shown to decrease post-MI MACE, more data are required confirm their safety efficacy in an unselected population. Therefore, we initiated the CLEAR SYNERGY (OASIS 9) trial address these uncertainties. The is a 2 × factorial randomized controlled 0.5 mg daily versus placebo 25 7,062 participants who were within 72...
BackgroundMineralocorticoid receptor antagonists have been shown to reduce mortality in patients after myocardial infarction with congestive heart failure. Whether routine use of spironolactone is beneficial uncertain.MethodsIn this multicenter trial a 2-by-2 factorial design, we randomly assigned who had undergone percutaneous coronary intervention receive either or placebo and colchicine placebo. The results the are reported here. two primary outcomes were composite death from...
The balloon-expandable Sapien-3 valve demonstrated superior results in terms of residual aortic regurgitation when compared with self-expandable devices. We aimed to compare for the first-time early outcomes transcatheter heart (THV) Myval device.Consecutive real-world patients from nine European institutions symptomatic severe stenosis treated either or THV devices after June 2018 were compared. Early clinical prospectively gathered and blinded analysis 30-day echocardiography was...
Importance In patients with multivessel coronary artery disease (CAD) presenting ST-segment elevation myocardial infarction (STEMI), complete revascularization reduces major cardiovascular events compared culprit lesion–only percutaneous intervention (PCI). Whether also improves angina-related health status is unknown. Objective To determine whether angina in STEMI and CAD. Design, Setting, Participants This secondary analysis of a randomized, multinational, open label trial patient-reported...
Abstract Background: Malnutrition is a relevant prognostic factor in cardiovascular disease. However, it has not been studied adults with CHD and Fontan circulation. Methods: Retrospective, single-centre cohort study including all consecutive Objectives: 1. To evaluate the prevalence of malnutrition, defined according to Controlling Nutritional Status score, which includes albumin, lymphocytes, cholesterol 2. assess its utility as marker. Results: We included 93 patients (55.9% male) mean...
The revascularization strategy to pursue in older myocardial infarction (MI) patients with multivessel disease (MVD) is currently unknown. For this reason, while waiting for the results of dedicated trials, we sought compare a complete versus culprit-only MI by merging data from four registries.The inclusion criteria target population present study were (i) age ≥ 75 years; (ii) (STE or NSTE); (iii) MVD; (iv) successful treatment culprit lesion. Propensity scores (PS) derived using logistic...
Background: The usefulness of drug-eluting balloons (DEBs) has not been fully elucidated in calcified coronary lesions (CCLs). This meta-analysis aimed to evaluate the efficacy DEBs compared a stent (DES) this setting. Methods: PubMed, EMBASE and Cochrane were searched through December 2023. primary endpoint was 12 months major adverse cardiac events (MACE). Secondary endpoints included clinical outcomes angiographic results after PCI at 12-month follow-up. Results: Five studies total 1141...
BACKGROUND: Stent underexpansion is a significant challenge in percutaneous coronary intervention, critically impacting patient outcomes. While excimer laser angioplasty (ELCA) and intravascular lithotripsy (IVL) are increasingly used to address this issue, their full impact on the integrity of drug-eluting stents remains unclear, raising concerns about safety efficacy. METHODS: This vitro study assessed effects ELCA IVL structural using scanning electron microscopy. Nine stents, 5 Onyx...
This EAPCI position statement provides guidance on safely restoring elective cardiac procedures during COVID-19 pandemic waves based the local situation and prioritizing patients according to clinical criteria.
Background: Patients with cardiogenic shock (CS) and mitral regurgitation (MI) have a prohibitive risk that contraindicates surgical treatment. Although the feasibility of transcatheter edge-to-edge therapy (TEER) has been demonstrated in this setting, benefit combined use TEER mechanical circulatory support devices (MCS) not studied. The aim study was to evaluate clinical outcomes patients MCS. Methods: MITRA-ASSIST is retrospective multicentre Spanish registry included MR CS who underwent...
Bicuspid aortic valve (BAV) is one of the most common congenital valvular heart diseases occurring in 0.5-2% general population, 2-6% patients with severe stenosis (AS) and up to 20% octo/nonagenarians undergoing surgery. In this regard, Transcatheter replacement (TAVR) has emerged as a therapeutic alternative. At present time, there not enough evidence determine which best approach for AS BAV. We report acute recoil following TAVR self-expanding prosthesis heavily calcified addition, we...
To study the agreement of Tuberculin Skin Tests (TST) and Interferon Gamma Release Assays (IGRA) when screening tuberculosis infection amongst inmates recently admitted to prison.Prospective conducted in a prison during months May June 2009. Inmates without TB history, with previous TST negatives or prior TSTs were included. Participants signed an informed consent form was approved by independent Ethical Committee. (positive 10 > = mm) IGRA (Quantiferon TB-Gold) performed standardized data...
Abstract Background Midterm data comparing clinical outcomes after successful implantation of self‐expanding and balloon‐expandable transcatheter heart valves (THV) are limited. We aimed to compare 2‐year aortic valve (TAVI) with the Edwards or Medtronic THV. Methods Two‐year were analyzed according implanted THV in GALILEO trial. Major adverse cardiac cerebrovascular events (MACCE) was a composite all‐cause death thromboembolic including stroke, myocardial infarction, symptomatic...
Concerns have been raised on a potential interaction between renin-angiotensin system inhibitors (RASI) and the susceptibility to coronavirus disease 2019 (COVID-19). No data so far reported prognostic impact of RASI in patients suffering from ST-elevation myocardial infarction (STEMI) during COVID-19 pandemic, which was aim present study. STEMI treated with primary percutaneous coronary intervention (PPCI) enrolled ISACS-STEMI registry were included sub-analysis divided according therapy at...