Manuel Pan
- Coronary Interventions and Diagnostics
- Cardiac Valve Diseases and Treatments
- Cardiac Imaging and Diagnostics
- Infective Endocarditis Diagnosis and Management
- Acute Myocardial Infarction Research
- Congenital Heart Disease Studies
- Cardiac Structural Anomalies and Repair
- Aortic Disease and Treatment Approaches
- Cardiovascular Function and Risk Factors
- Cardiac pacing and defibrillation studies
- Cardiac Arrhythmias and Treatments
- Cerebrovascular and Carotid Artery Diseases
- Peripheral Artery Disease Management
- Cardiovascular and Diving-Related Complications
- Cardiac, Anesthesia and Surgical Outcomes
- Coronary Artery Anomalies
- Atrial Fibrillation Management and Outcomes
- Mechanical Circulatory Support Devices
- Vascular Procedures and Complications
- Aortic aneurysm repair treatments
- Antiplatelet Therapy and Cardiovascular Diseases
- Heart Failure Treatment and Management
- Cardiac and Coronary Surgery Techniques
- Pulmonary Hypertension Research and Treatments
- Mesenchymal stem cell research
Hospital Universitario Reina Sofía
2016-2025
University of Córdoba
2016-2025
Centro de Investigación en Red en Enfermedades Cardiovasculares
2024-2025
Instituto Maimónides de Investigación Biomédica de Córdoba
2016-2025
Centro de Investigación Biomédica en Red
2024-2025
Red de Investigación Cardiovascular
2025
Instituto de Salud Carlos III
2025
Guangdong Medical College
2025
Affiliated Hospital of Hangzhou Normal University
2025
Institute for Research in Biomedicine
2016-2023
Percutaneous coronary intervention (PCI) of bifurcation lesions remains a subject debate. Many studies have been published in this setting. They are often small scale and display methodological flaws other shortcomings such as inaccurate designation lesions, heterogeneity, inadequate description techniques implemented.The aim is to propose consensus established by the European Bifurcation Club (EBC), on definition classification treatments implemented with purpose allowing comparisons...
Background— We aimed to determine the incidence, predictors, clinical characteristics, management, and outcomes of infective endocarditis (IE) after transcatheter aortic valve implantation (TAVI). Methods Results— This multicenter registry included 53 patients (mean age, 79±8 years; men, 57%) who suffered IE TAVI 7944 a mean follow-up 1.1±1.2 years (incidence, 0.67%, 0.50% within first year TAVI). Mean time from was 6 months (interquartile range, 1–14 months). Orotracheal intubation (hazard...
The European Bifurcation Club (EBC) is an independent, non-political and informal "think tank" of scientists with a particular interest in clinical, technical fundamental aspects the management coronary artery bifurcation disease. Bifurcations account for 15-20% all percutaneous interventions (PCI) remain one most challenging lesions interventional cardiology terms procedural success rate as well long-term cardiac events. optimal is, despite fast growing scientific literature, still subject...
The 15th European Bifurcation Club (EBC) meeting was held in Barcelona October 2019. It facilitated a renewed consensus on coronary bifurcation lesions (CBL) and unprotected left main (LM) percutaneous interventions. stenting techniques continue to be refined, developed tested. remains evident that provisional approach with optional side branch treatment utilising T, T small protrusion (TAP) or culotte continues provide flexible options for the majority of CBL patients. Debate persists...
Abstract Background Patients with non-left-main coronary bifurcation lesions are usually best treated a stepwise provisional approach. However, patients true left main stem have been shown in one dedicated randomized study to benefit from systematic dual stent implantation. Methods and results Four hundred sixty-seven requiring intervention were recruited the EBC MAIN 11 European countries. aged 71 ± 10 years; 77% male. randomly allocated layered strategy (n = 230) or approach 237). The...
Stepwise layered provisional stenting (PS) is the most commonly used strategy to treat coronary bifurcation lesions (CBL). The term 'stepwise layered' emphasises versatility of this approach that allows adjustment procedure plan according CBL complexity, starting with stent implantation in one branch and a second other only when required. A series refinements have been implemented over years facilitate achievement predictable procedural results using approach. However, despite its simplicity...
The European Bifurcation Club (EBC) supports a continuous review of the field coronary artery bifurcation interventions and aims to facilitate scientific discussion an exchange ideas on management disease. recent focus meetings consensus statements has been technical issues in stenting, recognising that final result procedure long-term outcome for our patients are strongly influenced by factors, including preprocedural strategy, stenting technique selection, performance optimal procedural...
There are limited head-to-head randomised trials comparing the performance of different transcatheter heart valves (THVs).
Background— For the treatment of coronary bifurcation lesions, a provisional strategy is superior to systematic 2-stent techniques for most lesions. However, complex anatomies with large side branches (SBs) significant ostial disease length are considered by expert consensus warrant technique upfront. This view has not been scientifically assessed. Methods and Results— Symptomatic patients caliber true lesions (SB diameter ≥2.5 mm) (≥5 were randomized either T-stent or dual stent culotte...
Defining the optimal conduction of percutaneous-coronary-intervention (PCI) to treat bifurcation lesions has been subject many clinical studies showing that applied stenting technique may influence outcome. Accordingly, classifications and technical sequences should be standardized allow proper reporting comparison.
The aim of this study was to describe the epidemiology, mechanisms, management, and outcomes coronary artery perforation during chronic total occlusion (CTO) percutaneous intervention (PCI).We included 1,811 consecutive patients undergoing CTO PCI at five centres between 2011 2018. Coronary observed in n=99 (5.5%). Patients with were older, had a higher J-CTO score, more often required antegrade dissection/re-entry retrograde approach, lower success rates. frequency Ellis type I, II, III...