Patricia J. Peña‐Orihuela
A5071751829- Nutritional Studies and Diet
- Diet and metabolism studies
- Obesity, Physical Activity, Diet
- Reproductive Biology and Fertility
- Cardiac Health and Mental Health
- COVID-19 and healthcare impacts
- Assisted Reproductive Technology and Twin Pregnancy
- Antioxidant Activity and Oxidative Stress
- Consumer Attitudes and Food Labeling
- Nuts composition and effects
- Long-Term Effects of COVID-19
- Adipose Tissue and Metabolism
- Reproductive Health and Technologies
- Obesity and Health Practices
- Cardiovascular Health and Risk Factors
- Health disparities and outcomes
- COVID-19 and Mental Health
- Per- and polyfluoroalkyl substances research
- Adipokines, Inflammation, and Metabolic Diseases
- Ovarian function and disorders
- Food Security and Health in Diverse Populations
- Lipoproteins and Cardiovascular Health
- Effects and risks of endocrine disrupting chemicals
- Coconut Research and Applications
- Tea Polyphenols and Effects
Instituto de Salud Carlos III
2012-2025
Hospital Universitario Reina Sofía
2021-2025
Instituto Maimónides de Investigación Biomédica de Córdoba
2012-2024
University of Córdoba
2012-2024
Centro de Investigación Biomédica en Red
2015-2024
Universidade Católica de Petrópolis
2024
Magna Graecia University
2024
Spanish Biomedical Research Centre in Physiopathology of Obesity and Nutrition
2021-2023
Cordoba University
2021
Hospital Nacional Cayetano Heredia
2015
Dietary patterns can produce an environmental impact. Changes in people's diet, such as the increased consumption of ultra-processed food (UPF) not only influence human health but also environment sustainability.Assessment impact 2-year changes UPF on greenhouse gas emissions and water, energy land use.A longitudinal study after a dietary intervention including 5879 participants from Southern European population between ages 55-75 years with metabolic syndrome.Food intake was assessed using...
This article aims to estimate the differences in environmental impact (greenhouse gas [GHG] emissions, land use, energy used, acidification and potential eutrophication) after one year of promoting a Mediterranean diet (MD). Baseline 1-year follow-up data from 5800 participants PREDIMED-Plus study were used. Each participant's food intake was estimated using validated semi-quantitative frequency questionnaires, adherence MD Dietary Score. The influence on assessed through EAT-Lancet...
Previous evidence supports the important role that oxidative stress (OxS) plays in metabolic syndrome (MetS)-related manifestations. We determined relationship between number of MetS components and degree OxS patients. In this comparative cross-sectional study from LIPGENE cohort, a total 91 patients (43 men 48 women; aged 45 68 years) were divided into four groups based on components: subjects with 2, 3, 4 5 (n=20, 31, 28 12, respectively). measured ischemic reactive hyperemia (IRH), plasma...
Background Food insecurity is linked to poorer cardiovascular health (CVH) outcomes, particularly in underresourced communities, where social determinants of play a critical role. Despite the recognized connections, there remains lack empirical evidence delineating implications food on CVH. CVH, broader concept than disease, encompasses overall well‐being system and supported by favorable lifestyle choices physiological metrics. Particularly study CVH could provide valuable insights for...
Journal Article Predictive value of human chorionic gonadotrophin in the outcome early pregnancy after in-vitro fertilization and spontaneous conception Get access F. Zegers-Hochschild, Zegers-Hochschild 1 Unit Reproductive Medicine, Clínica Las CondesLo Fontecilla 441, Condes, Santiago, Chile 1To whom correspondence should be addressed Search for other works by this author on: Oxford Academic PubMed Google Scholar E. Altieri, Altieri C. Fabres, Fabres Fernández, Fernández A. Mackenna,...
Metabolic syndrome is a multi-component disorder associated to high risk of cardiovascular disease. Its etiology the result complex interaction between genetic and environmental factors, including dietary habits. We aimed identify target proteins modulated by long-term consumption four diets differing in quality quantity lipids whole proteome peripheral blood mononuclear cells (PBMC). A randomized, controlled trial conducted within LIPGENE study assigned 24 MetS patients for 12 weeks each 1...
Tree nuts and peanuts (henceforth, nuts) are nutrient-dense foods rich in neuroprotective components; thus, their consumption could benefit cognitive health. However, evidence to date is limited inconsistent regarding the potential benefits of for function.To prospectively evaluate association between nut 2-y changes performance older adults at decline risk.A total 6,630 participants aged 55 75 y (mean age 65.0±4.9 y, 48.4% women) with overweight/obesity metabolic syndrome completed a...
Objective: To evaluate the impact of patient follicular environment with oxidative stress on oocyte quality.Methods: Patients fertility treatment either advanced maternal age or endometriosis were asked to donate fluid collected during ovum pick-up.Follicular (FF) was added (20%, 10% and 5%; %V/V) in vitro maturation (IVM) medium mouse oocytes.Following culture, oocytes assessed for meiosis reinitiation.In a second setup, coenzyme Q10 culture FF.In addition assessing meiotic maturation,...
The principal source of exposure to Polychlorinated dibenzo-p-dioxins and polychlorinated dibenzo-p-furans (PCDD/Fs) in humans comes from food intake. PCDD/Fs, are a family potential endocrine disruptors have been associated with different chronic diseases such as diabetes hypertension. However, studies assessing the relationship between dietary PCDD/Fs adiposity or obesity status middle-aged population limited. To assess cross-sectionally longitudinally associations estimated intake (DI)...
Abstract Background The coronavirus disease 2019 (COVID-19) has serious physiological and psychological consequences. long-term (>12 weeks post-infection) impact of COVID-19 on mental health, specifically in older adults, is unclear. We longitudinally assessed the association with depression symptomatology community-dwelling adults metabolic syndrome within framework PREDIMED-Plus cohort. Methods Participants ( n = 5486) aged 55–75 years were included this longitudinal status...
Abstract Background Peripheral artery disease (PAD) is recognized as a significant predictor of mortality and adverse cardiovascular outcomes in patients with coronary heart (CHD). In fact, coexisting PAD CHD strongly associated greater event recurrence compared either one them alone. High-density lipoprotein (HDL)-mediated cholesterol efflux capacity (CEC) found to be inversely an increased risk incident CHD. However, this association not established the context secondary prevention. sense,...
Background Helping consumers to improve the nutritional quality of their diet is a key public health action prevent cardiovascular diseases (CVDs). The modified version Food Standard Agency Nutrient Profiling System Dietary Index (FSAm-NPS DI) underpinning Nutri-Score front-of-pack label has been used in strategies address deleterious consequences poor diets. This study aimed assess association between FSAm-NPS DI and some CVD risk factors including body mass index (BMI), waist...
We tested the effects of a weight-loss intervention encouraging energy-reduced MedDiet and physical activity (PA) in comparison to ad libitum on COVID-19 incidence older adults.
Endocrine disruptors (EDs) have emerged as potential contributors to the development of type-2 diabetes. Perfluorooctane sulfonate (PFOS), is one these EDs linked with chronic diseases and gathered attention due its widespread in food.
<p><strong>Background</strong></p> <p>The coronavirus disease 2019 (COVID-19) has serious physiological and psychological consequences. The long-term (>12 weeks post-infection) impact of COVID-19 on mental health, specifically in older adults, is unclear. We longitudinally assessed the association with depression symptomatology community-dwelling adults metabolic syndrome within framework PREDIMED-Plus cohort.</p>...
<p><strong>Objective</strong></p> <p>This article aims to estimate the differences in environmental impact (greenhouse gas [GHG] emissions, land use, energy used, acidification and potential eutrophication) after one year of promoting a Mediterranean diet (MD).</p> <p><strong>Methods</strong></p> <p>Baseline 1-year follow-up data from 5800 participants PREDIMED-Plus study were used. Each participant's food intake was estimated...
The aim of our cross-sectional and longitudinal study is to assess the relationship between daytime night-time sleep duration health-related quality life (HRQoL) in adults with metabolic syndrome after a 1-year healthy lifestyle intervention. Analysis data from 2119 Spanish aged 55-75 years PREDIMED-Plus was performed. Sleep assessed using wrist-worn accelerometer. HRQoL measured SF-36 questionnaire. Linear regression models adjusted for socioeconomic factors morbidity were developed. In...
Endothelial dysfunction is a key player in both the onset and development of atherosclerosis. No study has examined whether healthy dietary patterns can improve microvascular endothelial function patients with coronary heart disease (CHD) long-term this relationship affect patient's risk CHD recurrence. In CORDIOPREV study, randomized, double-blind, controlled trial, intervention either Mediterranean diet or low-fat was implemented 1,002 patients. A laser-doppler flowmetry performed at...