A5089303763- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Acute Myocardial Infarction Research
- Cardiac Valve Diseases and Treatments
- Parathyroid Disorders and Treatments
- Peripheral Artery Disease Management
- Cardiovascular Function and Risk Factors
- Cerebrovascular and Carotid Artery Diseases
- Cardiac electrophysiology and arrhythmias
- Cardiac pacing and defibrillation studies
- Cardiac Arrhythmias and Treatments
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Structural Anomalies and Repair
- Chemotherapy-induced cardiotoxicity and mitigation
- Vitamin D Research Studies
- Vascular Procedures and Complications
- Advanced MRI Techniques and Applications
- Blood Pressure and Hypertension Studies
- Medical Imaging and Pathology Studies
- Takotsubo Cardiomyopathy and Associated Phenomena
- Cardiac Health and Mental Health
- Dialysis and Renal Disease Management
- Heart Rate Variability and Autonomic Control
- Pharmacological Effects and Toxicity Studies
University of Palermo
2019-2025
Azienda Ospedaliera Universitaria Policlinico "Paolo Giaccone" di Palermo
2020-2025
University of Palermo
2024
St. Eugenio Hospital
2024
All India Institute of Medical Sciences
2024
AOL (United States)
2006-2023
Royal Brompton & Harefield NHS Foundation Trust
2021-2023
Shaheed Rajaei Cardiovascular Medical and Research Center
2023
Iran University of Medical Sciences
2023
Saint Laurent Polyclinique
2023
The clinical value of percutaneous coronary intervention (PCI) for chronic total occlusions (CTOs) is not established by randomized trials. This study should compare the benefit PCI vs. optimal medical therapy (OMT) on health status in patients with at least one CTO.Three hundred and ninety-six were enrolled a prospective randomized, multicentre, open-label, controlled trial to treatment OMT 2:1 randomization ratio. primary endpoint was change assessed Seattle angina questionnaire (SAQ)...
In comparison with non-occlusive lesions, percutaneous coronary intervention (PCI) of chronic total occlusions (CTO) represents a greater challenge for the interventionalist, due to lower procedural success rates, relatively higher incidence complications and increased rate restenosis. The European Registry Chronic Total Occlusion (ERCTO) was created goal evaluating real impact CTO PCI in context, trying analyse rates success, technical information from procedures patient outcome.Data...
Percutaneous coronary intervention (PCI) of bifurcation lesions remains a subject debate. Many studies have been published in this setting. They are often small scale and display methodological flaws other shortcomings such as inaccurate designation lesions, heterogeneity, inadequate description techniques implemented.The aim is to propose consensus established by the European Bifurcation Club (EBC), on definition classification treatments implemented with purpose allowing comparisons...
Since its inception in December 2006, the EuroCTO Club has strived to provide framework for state-of-the-art chronic total occlusion (CTO) percutaneous coronary intervention (PCI) Europe and nearby regions. Among initiatives, published a set of recommendations regarding technical aspects CTO PCI, whose last edition dates 2012. The consensus document discusses PCI clinical indications, techniques equipment use, as well qualifications operators/centres. Given considerable amount progress made...
Over the past 2 decades, chronic total occlusion (CTO) percutaneous coronary intervention has developed into its own subspecialty of interventional cardiology. Dedicated terminology, techniques, devices, courses, and training programs have enabled progressive advancements. However, only a few randomized trials been performed to evaluate safety efficacy CTO intervention. Moreover, several published observational studies shown conflicting data. Part paucity clinical data stems from fact that...
Through contemporary literature, the optimal strategy to manage coronary chronic total occlusions (CTOs) remains under debate. The aim of Italian Registry Chronic Total Occlusions (IRCTO) was provide data on prevalence, characteristics, and outcome CTO patients according management strategy. IRCTO is a prospective real world multicentre registry enrolling showing at least one CTO. Clinical angiographic were collected independently from therapeutic [optimal medical therapy (MT), percutaneous...
Chronic total occlusions (CTOs) of coronary arteries can be found in the context chronic or acute syndromes; sometimes they are an incidental finding those apparently healthy individuals undergoing imaging for preoperative risk assessment. Recently, invasive management CTOs has made impressive progress due to sophisticated preinterventional assessment, including advanced non-invasive imaging, availability novel and dedicated tools CTO percutaneous intervention (PCI), experienced...
BACKGROUND Oxygen-15-labeled water is a diffusible, metabolically inert myocardial blood flow tracer with short half-life (2 minutes) that can be used quantitatively positron emission tomography (PET). The purpose of this study was to validate new technique quantify (MBF) in animals and assess its application patients. METHODS AND RESULTS involves the administration 15O-labeled carbon dioxide (C15O2) rapid dynamic scanning. Arterial time activity curves were fitted single tissue compartment...
The intravenous infusion of adenosine provokes anginalike chest pain. To establish its origin, an intracoronary increasing concentrations was given in 22 patients with stable angina pectoris. During infusion, 20 had pain without electrocardiographic signs ischemia. They all reported that the similar to their usual anginal In 10 also infused into right atrium, but it never produced symptoms at doses provoked during infusion. seven other patients, repeated after administration aminophylline,...
Recanalisation rates of coronary chronic total occlusions (CTO) remain sub-optimal. The retrograde technique was recently introduced to improve success rates.From February 2005 until December 2007, 175 patients were treated with this in seven European centres by highly experienced operators: 84 (48%) as primary strategy, 41 (23.5%) immediately after antegrade failure and 50 (28.5%) a repeat procedure previous failure. Baseline characteristics revealed mean age 61.4 +/- 10.8 years 29.5% 39%...
The study focuses on the evolution of practice, procedural outcomes, and in-hospital complications chronic total occlusion percutaneous coronary intervention in Europe.Data from 17 626 procedures enrolled European Registry Chronic Total Occlusion between January 2008 June 2015 were assessed. mean patient age was 63.9±10.9 years; 85% men. Procedural success increased 79.7% to 89.3% through period. Patients during years had increasing comorbidities lesion complexity (J-CTO score [Multicenter...
Percutaneous coronary intervention (PCI) for chronic total occlusions (CTO) improves clinical symptoms and quality of life. The longer-term safety PCI compared to optimal medical therapy (OMT) remains uncertain.
Percutaneous coronary interventions (PCI) of chronic total occlusions (CTO) have reached high procedural success rates thanks to dedicated equipment, evolving techniques, and worldwide adoption state-of-the-art crossing algorithms.
The term MINOCA (Myocardial Infarction with Non-Obstructive Coronary Arteries) refers to myocardial infarction cases where coronary arteries exhibit less than 50 % stenosis. encompasses a diverse range of pathologies varying etiologies. Diagnosis involves meeting acute criteria and excluding other causes (myocarditis, takotsubo syndrome). Clinical features often resemble those traditional infarction, but patients tend be younger more frequently female. Etiological investigations include...