- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Acute Myocardial Infarction Research
- Cardiac Valve Diseases and Treatments
- Antiplatelet Therapy and Cardiovascular Diseases
- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular Function and Risk Factors
- Peripheral Artery Disease Management
- Aortic aneurysm repair treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac electrophysiology and arrhythmias
- Cardiac Arrhythmias and Treatments
- Growth Hormone and Insulin-like Growth Factors
- Infective Endocarditis Diagnosis and Management
- Heart Failure Treatment and Management
- Cardiac Arrest and Resuscitation
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac and Coronary Surgery Techniques
- Diabetes Management and Research
- Cardiac pacing and defibrillation studies
- Cardiovascular Syncope and Autonomic Disorders
- Venous Thromboembolism Diagnosis and Management
- Health Systems, Economic Evaluations, Quality of Life
- Aortic Disease and Treatment Approaches
- Lipoproteins and Cardiovascular Health
Aalborg University Hospital
2015-2025
Aalborg University
2011-2021
Aarhus University
2007-2016
Aarhus University Hospital
2006-2015
Regionshospitalet Herning
2012-2014
Odense University Hospital
2007-2014
Rigshospitalet
2007-2013
Copenhagen University Hospital
2013
Maastricht University Medical Centre
2013
Université de Montpellier
2013
For the treatment of myocardial infarction with ST-segment elevation, primary angioplasty is considered superior to fibrinolysis for patients who are admitted hospitals facilities. Whether this benefit maintained require transportation from a community hospital center where invasive available uncertain.We randomly assigned 1572 acute or accelerated intravenous alteplase; 1129 were enrolled at 24 referral and 443 5 invasive-treatment centers. The study end point was composite death, clinical...
Background— The optimal stenting strategy in coronary artery bifurcation lesions is unknown. In the present study, a of both main vessel and side branch (MV+SB) was compared with only, optional (MV), sirolimus-eluting stents. Methods Results— A total 413 patients lesion were randomized. primary end point major adverse cardiac event: death, myocardial infarction, target-vessel revascularization, or stent thrombosis after 6 months. At months, there no significant differences rates events...
AimsExenatide, a glucagon-like-peptide-1 analogue, increases myocardial salvage in experimental settings with coronary occlusion and subsequent reperfusion. We evaluated the cardioprotective effect of exenatide at time reperfusion patients ST-segment elevation infarction (STEMI) treated primary percutaneous intervention (pPCI).
In comparison with non-occlusive lesions, percutaneous coronary intervention (PCI) of chronic total occlusions (CTO) represents a greater challenge for the interventionalist, due to lower procedural success rates, relatively higher incidence complications and increased rate restenosis. The European Registry Chronic Total Occlusion (ERCTO) was created goal evaluating real impact CTO PCI in context, trying analyse rates success, technical information from procedures patient outcome.Data...
Spontaneous coronary artery dissection (SCAD) is a rare cause of acute syndrome (ACS) that associates with high acute-phase mortality rate, whereas long-term outcome less well described.To describe the incidence, predictors, and prognosis SCAD.Retrospective case-identification study from Western Denmark Heart Registry database Forensic Institute at Aarhus University 1999 through 2007.SCAD was documented in 22 32,869 (0.7 per thousand) angiograms angiographic registry. The SCAD incidence...
Background— The first generation of the bioresorbable everolimus drug-eluting vascular scaffold showed signs shrinkage at 6 months, which largely contributed to late luminal loss. Nevertheless, loss was less than that observed with bare metal stents. To maintain mechanical integrity device up design and manufacturing process its polymer were modified. Methods Results— Quantitative coronary angiography, intravascular ultrasound analysis radiofrequency backscattering, as an optional...
It is unknown whether the preferred 1-stent bifurcation stenting approach with of main vessel (MV) and optional side branch using drug-eluting stents should be finalized by a kissing balloon dilatation (FKBD). Therefore, we compared strategies MV without FKBD.We randomized 477 patients lesion to FKBD (n=238) or no (n=239) after stenting. The primary end point was major adverse cardiac events: death, non-procedure-related index myocardial infarction, target revascularization, stent thrombosis...
BackgroundRemote ischaemic conditioning with transient ischaemia and reperfusion applied to the arm has been shown reduce myocardial infarct size in patients ST-elevation infarction (STEMI) undergoing primary percutaneous coronary intervention (PPCI). We investigated whether remote could incidence of cardiac death hospitalisation for heart failure at 12 months.MethodsWe did an international investigator-initiated, prospective, single-blind, randomised controlled trial (CONDI-2/ERIC-PPCI) 33...
To assess observations with multimodality imaging of the Absorb bioresorbable everolimus-eluting vascular scaffold performed in two consecutive cohorts patients who were serially investigated either at 6 and 24 months or 12 36 months.In ABSORB multicentre single-arm trial, 45 (cohort B1) 56 B2) underwent serial invasive imaging, specifically quantitative coronary angiography (QCA), intravascular ultrasound (IVUS), radiofrequency backscattering (IVUS-VH) optical coherence tomography (OCT)....
Intracoronary polymer-based stent delivery of paclitaxel has been shown to be effective in reducing restenosis simple coronary lesions, but the evidence base for contemporary use longer, more complex stenoses is lacking.TAXUS VI a prospective, multicenter, double-blind, randomized trial assessing clinical and angiographic outcomes TAXUS Moderate Release paclitaxel-eluting treatment long, artery lesions. Four hundred forty-eight patients at 44 sites were (1:1) between drug-eluting Express2 an...