Leif Thuesen

ORCID: 0000-0003-0916-9868
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Coronary Interventions and Diagnostics
  • Cardiac Imaging and Diagnostics
  • Acute Myocardial Infarction Research
  • Cardiac Valve Diseases and Treatments
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Cerebrovascular and Carotid Artery Diseases
  • Cardiovascular Function and Risk Factors
  • Peripheral Artery Disease Management
  • Aortic aneurysm repair treatments
  • Atrial Fibrillation Management and Outcomes
  • Cardiac electrophysiology and arrhythmias
  • Cardiac Arrhythmias and Treatments
  • Growth Hormone and Insulin-like Growth Factors
  • Infective Endocarditis Diagnosis and Management
  • Heart Failure Treatment and Management
  • Cardiac Arrest and Resuscitation
  • Cardiac, Anesthesia and Surgical Outcomes
  • Cardiac and Coronary Surgery Techniques
  • Diabetes Management and Research
  • Cardiac pacing and defibrillation studies
  • Cardiovascular Syncope and Autonomic Disorders
  • Venous Thromboembolism Diagnosis and Management
  • Health Systems, Economic Evaluations, Quality of Life
  • Aortic Disease and Treatment Approaches
  • Lipoproteins and Cardiovascular Health

Aalborg University Hospital
2015-2025

Aalborg University
2011-2021

Aarhus University
2007-2016

Aarhus University Hospital
2006-2015

Regionshospitalet Herning
2012-2014

Odense University Hospital
2007-2014

Rigshospitalet
2007-2013

Copenhagen University Hospital
2013

Maastricht University Medical Centre
2013

Université de Montpellier
2013

For the treatment of myocardial infarction with ST-segment elevation, primary angioplasty is considered superior to fibrinolysis for patients who are admitted hospitals facilities. Whether this benefit maintained require transportation from a community hospital center where invasive available uncertain.We randomly assigned 1572 acute or accelerated intravenous alteplase; 1129 were enrolled at 24 referral and 443 5 invasive-treatment centers. The study end point was composite death, clinical...

10.1056/nejmoa025142 article EN New England Journal of Medicine 2003-08-20

Background— The optimal stenting strategy in coronary artery bifurcation lesions is unknown. In the present study, a of both main vessel and side branch (MV+SB) was compared with only, optional (MV), sirolimus-eluting stents. Methods Results— A total 413 patients lesion were randomized. primary end point major adverse cardiac event: death, myocardial infarction, target-vessel revascularization, or stent thrombosis after 6 months. At months, there no significant differences rates events...

10.1161/circulationaha.106.664920 article EN Circulation 2006-10-24

AimsExenatide, a glucagon-like-peptide-1 analogue, increases myocardial salvage in experimental settings with coronary occlusion and subsequent reperfusion. We evaluated the cardioprotective effect of exenatide at time reperfusion patients ST-segment elevation infarction (STEMI) treated primary percutaneous intervention (pPCI).

10.1093/eurheartj/ehr309 article EN European Heart Journal 2011-09-14

In comparison with non-occlusive lesions, percutaneous coronary intervention (PCI) of chronic total occlusions (CTO) represents a greater challenge for the interventionalist, due to lower procedural success rates, relatively higher incidence complications and increased rate restenosis. The European Registry Chronic Total Occlusion (ERCTO) was created goal evaluating real impact CTO PCI in context, trying analyse rates success, technical information from procedures patient outcome.Data...

10.4244/eijv7i4a77 article EN EuroIntervention 2011-08-01

Spontaneous coronary artery dissection (SCAD) is a rare cause of acute syndrome (ACS) that associates with high acute-phase mortality rate, whereas long-term outcome less well described.To describe the incidence, predictors, and prognosis SCAD.Retrospective case-identification study from Western Denmark Heart Registry database Forensic Institute at Aarhus University 1999 through 2007.SCAD was documented in 22 32,869 (0.7 per thousand) angiograms angiographic registry. The SCAD incidence...

10.1002/ccd.22115 article EN Catheterization and Cardiovascular Interventions 2009-05-06

Background— The first generation of the bioresorbable everolimus drug-eluting vascular scaffold showed signs shrinkage at 6 months, which largely contributed to late luminal loss. Nevertheless, loss was less than that observed with bare metal stents. To maintain mechanical integrity device up design and manufacturing process its polymer were modified. Methods Results— Quantitative coronary angiography, intravascular ultrasound analysis radiofrequency backscattering, as an optional...

10.1161/circulationaha.110.970772 article EN Circulation 2010-11-16

It is unknown whether the preferred 1-stent bifurcation stenting approach with of main vessel (MV) and optional side branch using drug-eluting stents should be finalized by a kissing balloon dilatation (FKBD). Therefore, we compared strategies MV without FKBD.We randomized 477 patients lesion to FKBD (n=238) or no (n=239) after stenting. The primary end point was major adverse cardiac events: death, non-procedure-related index myocardial infarction, target revascularization, stent thrombosis...

10.1161/circulationaha.110.966879 article EN Circulation 2010-12-21
Derek J. Hausenloy Rajesh Kharbanda Ulla Møller Manish Ramlall Jens Aarøe and 95 more Robert J. Butler Heerajnarain Bulluck Tim Clayton Ali Dana Matthew Dodd Thomas Engstrøm Richard D. Evans Jens Flensted Lassen Erika Frischknecht Christensen José M. García‐Ruiz Diana A Gorog Jakob Hjort R. Houghton Borja Ibáñez Rosemary Knight Freddy Lippert Jacob Thomsen Lønborg Michael Mæng Dejan Milasinovic Ranjit More Jennifer M. Nicholas Lisette Okkels Jensen Alexander Perkins Nebojša Radovanović Roby Rakhit Jan Ravkilde Alisdair Ryding Michael Rahbek Schmidt Ingunn S. Riddervold Henrik Toft Sørensen Goran Stanković Madhusudhan Varma Ian Webb Christian Juhl Terkelsen John P. Greenwood Derek M. Yellon Hans Erik Bøtker Anders Junker Anne Kaltoft Morten Madsen Evald Høj Christiansen Lars Jakobsen Steen Carstensen Steen Dalby Kristensen Troels Thim Karen E. Pedersen Marianne Korsgaard Allan Iversen Erik Jørgensen Francis R. Joshi Frants Pedersen Hans Henrik Tilsted Karam Alzuhairi Kari Saunamäki Lene Holmvang Ole Ahlehof Rikke Sørensen Steffen Helqvist B. Màrk Anton Boel Villadsen Bent Raungaard Leif Thuesen M. Christiansen Phillip Freeman Svend Eggert Jensen Charlotte Schmidt Skov Ahmed Aziz Henrik Hansen Julia Ellert Karsten Tange Veien Knud Erik Pedersen Knud Hansen Ole Ahlehoff Helle Cappelen Daniel Wittrock Poul Anders Hansen Jens Peter Ankersen Kathryn Hedegaard John Kempel Henning Kaus Dennis Erntgaard Henrik D. Pedersen Matthias Giebner Troels Martin Hansen Mina Radovanović Maja Prodanović Lidija Savić Marijana Pejic Dragan Matić Ana Ušćumlić Ida Subotić Ratko Lasica Vladan Vukcevic Alfonso Suárez Beatriz Samaniego

BackgroundRemote ischaemic conditioning with transient ischaemia and reperfusion applied to the arm has been shown reduce myocardial infarct size in patients ST-elevation infarction (STEMI) undergoing primary percutaneous coronary intervention (PPCI). We investigated whether remote could incidence of cardiac death hospitalisation for heart failure at 12 months.MethodsWe did an international investigator-initiated, prospective, single-blind, randomised controlled trial (CONDI-2/ERIC-PPCI) 33...

10.1016/s0140-6736(19)32039-2 article EN cc-by The Lancet 2019-09-06

To assess observations with multimodality imaging of the Absorb bioresorbable everolimus-eluting vascular scaffold performed in two consecutive cohorts patients who were serially investigated either at 6 and 24 months or 12 36 months.In ABSORB multicentre single-arm trial, 45 (cohort B1) 56 B2) underwent serial invasive imaging, specifically quantitative coronary angiography (QCA), intravascular ultrasound (IVUS), radiofrequency backscattering (IVUS-VH) optical coherence tomography (OCT)....

10.4244/eijv9i11a217 article EN EuroIntervention 2014-02-01

Intracoronary polymer-based stent delivery of paclitaxel has been shown to be effective in reducing restenosis simple coronary lesions, but the evidence base for contemporary use longer, more complex stenoses is lacking.TAXUS VI a prospective, multicenter, double-blind, randomized trial assessing clinical and angiographic outcomes TAXUS Moderate Release paclitaxel-eluting treatment long, artery lesions. Four hundred forty-eight patients at 44 sites were (1:1) between drug-eluting Express2 an...

10.1161/circulationaha.105.552190 article EN Circulation 2005-11-15
Coming Soon ...