- Venous Thromboembolism Diagnosis and Management
- Pregnancy and Medication Impact
- Pregnancy and preeclampsia studies
- Birth, Development, and Health
- Atrial Fibrillation Management and Outcomes
- Inflammatory mediators and NSAID effects
- Antiplatelet Therapy and Cardiovascular Diseases
- Acute Myocardial Infarction Research
- Lipoproteins and Cardiovascular Health
- Colorectal Cancer Screening and Detection
- Cardiac Imaging and Diagnostics
- Health Systems, Economic Evaluations, Quality of Life
- Cancer Risks and Factors
- Coronary Interventions and Diagnostics
- Pneumonia and Respiratory Infections
- Liver Disease Diagnosis and Treatment
- Estrogen and related hormone effects
- Cardiac, Anesthesia and Surgical Outcomes
- Diabetes Treatment and Management
- Chronic Disease Management Strategies
- Inflammatory Bowel Disease
- Gestational Diabetes Research and Management
- Gastric Cancer Management and Outcomes
- Cancer, Lipids, and Metabolism
- Global Cancer Incidence and Screening
Aarhus University Hospital
2016-2025
Aarhus University
2016-2025
Stanford University
2016-2025
Boston University
2015-2025
Mountain Area Health Education Center
2025
AstraZeneca (Sweden)
1998-2024
Dartmouth College
2005-2024
Aalborg University
1996-2024
Brigham and Women's Hospital
2011-2024
Steno Diabetes Centers
2021-2024
Routinely collected health data, obtained for administrative and clinical purposes without specific a priori research goals, are increasingly used research. The rapid evolution availability of these data have revealed issues not addressed by existing reporting guidelines, such as Strengthening the Reporting Observational Studies in Epidemiology (STROBE). REporting studies Conducted using Data (RECORD) statement was created to fill gaps. RECORD an extension STROBE address items observational...
Introduction: Individual-level data on all prescription drugs sold in Danish community pharmacies has since 1994 been recorded the Register of Medicinal Products Statistics Medicines Agency. Content: The register subset, termed National Prescription Registry (DNPR), contains information dispensed prescriptions, including variables at level drug user, prescriber, and pharmacy. Validity coverage: Reimbursement-driven record keeping, with automated bar-code-based entry provides high quality,...
Little is known about the prognosis of cancer discovered during or after an episode venous thromboembolism.
Accurate population-based data are needed on the incidence of esophageal adenocarcinoma and high-grade dysplasia among patients with Barrett's esophagus.We conducted a nationwide, population-based, cohort study involving all esophagus in Denmark during period from 1992 through 2009, using Danish Pathology Registry Cancer Registry. We determined rates (numbers cases per 1000 person-years) dysplasia. As measure relative risk, standardized ratios were calculated use national cancer period.We...
The Charlson comorbidity index is often used to control for confounding in research based on medical databases. There are few studies of the accuracy codes obtained from these We examined positive predictive value (PPV) ICD-10 diagnostic coding Danish National Registry Patients (NRP) 19 conditions.Among all hospitalizations Northern Denmark between 1 January 1998 and 31 December 2007 with a first-listed diagnosis condition NRP, we selected 50 hospital contacts each condition. reviewed...
Background: It is well known that the time from conception to early childhood has importance for health conditions reach into later stages of life. Recent research supports this view, and diseases such as cardiovascular morbidity, cancer, mental illnesses, asthma, allergy may all have component causes act in Exposures period, which infl uence fetal growth, cell divisions, organ functioning, long-lasting impact on disease susceptibility. Methods: To investigate these issues Danish National...
Background: The expected survival of HIV-infected patients is major public health interest. Objective: To estimate time and age-specific mortality rates an population compared with that the general population. Design: Population-based cohort study. Setting: All persons receiving care in Denmark from 1995 to 2005. Patients: Each member nationwide Danish HIV Cohort Study was matched as many 99 according sex, date birth, municipality residence. Measurements: authors computed Kaplan–Meier life...
Parkinson's disease (PD) may be caused by an enteric neurotropic pathogen entering the brain through vagal nerve, a process that take over 20 years. We investigated risk of PD in patients who underwent vagotomy and hypothesized truncal is associated with protective effect, whereas superselective has minor effect.We constructed cohorts all Denmark during 1977-1995 matched general population cohort linking Danish registries. used Cox regression to compute hazard ratios (HRs) for corresponding...
Objective The majority of cardiovascular diagnoses in the Danish National Patient Registry (DNPR) remain to be validated despite extensive use epidemiological research. We therefore examined positive predictive value (PPV) DNPR. Design Population-based validation study. Setting 1 university hospital and 2 regional hospitals Central Denmark Region, 2010–2012. Participants For each diagnosis, up 100 patients from participating were randomly sampled during study period using Main outcome...
Several small studies have indicated an association between deep venous thrombosis or pulmonary embolism and a subsequent diagnosis of cancer, but the subject is controversial.We conducted nationwide study cohort patients with that was drawn from Danish National Registry Patients for years 1977 through 1992. The occurrence cancer in determined by linkage to Cancer Registry. expected number cases estimated on basis national age-, sex-, site-specific incidence rates.A total 15,348 11,305 were...
The clinical course of alcoholic cirrhosis, a condition with high mortality, has not been well described. We examined prevalence, risk, chronology, and mortality associated three complications cirrhosis: ascites, variceal bleeding, hepatic encephalopathy. followed population-based cohort 466 Danish patients diagnosed cirrhosis in 1993–2005, starting from the date hospital diagnosis ending August 2006. Data were extracted medical charts during follow-up period. Risk calculated using...
<b>Objectives</b> To examine 25 year trends in first time hospitalisation for acute myocardial infarction Denmark, subsequent short and long term mortality, the prognostic impact of sex comorbidity. <b>Design</b> Nationwide population based cohort study using medical registries. <b>Setting</b> All hospitals Denmark. <b>Subjects</b> 234 331 patients with a from 1984 through 2008. <b>Main outcome measures</b> Standardised incidence rate 30 day 31–365 mortality by sex. Comorbidity...
In pharmacoepidemiology, routinely collected data from electronic health records (including primary care databases, registries, and administrative healthcare claims) are a resource for research evaluating the real world effectiveness safety of medicines. Currently available guidelines reporting using non-randomised, data—specifically REporting studies Conducted Observational Routinely Data (RECORD) Strengthening Reporting OBservational in Epidemiology (STROBE) statements—do not capture...
OBJECTIVES: It is known that liver disease can cause an imbalance in the coagulation system, but available data on and risk of venous thromboembolism are conflicting. We examined patients hospitalized with diseases. METHODS: conducted a nationwide Danish case-control study incident cases from 1980 to 2005 using population-based National Registry Patients, Civil Registration System. used conditional logistic regression compute relative compared population controls. then excluded malignancy...