A5012392213- Statistical Methods and Inference
- Statistical Methods and Bayesian Inference
- Bipolar Disorder and Treatment
- Advanced Causal Inference Techniques
- Liver Disease Diagnosis and Treatment
- Statistical Methods in Clinical Trials
- Statistical Distribution Estimation and Applications
- Insurance, Mortality, Demography, Risk Management
- Schizophrenia research and treatment
- Health disparities and outcomes
- Health Systems, Economic Evaluations, Quality of Life
- Bayesian Methods and Mixture Models
- Advanced Statistical Methods and Models
- Suicide and Self-Harm Studies
- Adolescent and Pediatric Healthcare
- Liver Disease and Transplantation
- Treatment of Major Depression
- Mental Health Treatment and Access
- Birth, Development, and Health
- Global Cancer Incidence and Screening
- Pharmacological Effects and Toxicity Studies
- Cancer Risks and Factors
- Alcohol Consumption and Health Effects
- Tryptophan and brain disorders
- Electroconvulsive Therapy Studies
University of Copenhagen
2015-2024
Adama (Israel)
2019
Nationale Instelling voor Radioactief Aval en verijkte Splijtstoffen
2017
Statens Serum Institut
1996-2016
Rigshospitalet
1983-2016
Aalborg University
2015-2016
Copenhagen University Hospital
2015-2016
Cancer Research And Biostatistics
2016
Glostrup Hospital
2016
Aalborg University Hospital
2015
Data Envelopment Analysis (DEA) evaluates the relative efficiency of decision-making units (DMUs) but does not allow for a ranking efficient themselves. A modified version DEA based upon comparison DMUs to reference technology spanned by all other is developed. The procedure provides framework and facilitates with rankings on parametric methods.
Modern survival analysis and more general event history may be effectively handled in the mathematical framework of counting processes, stochastic integration, martingale central limit theory product integration. This book presents this theory, which has been subject an intense research activity during past one-and-a-half decades. The exposition is integrated with careful presentation many practical examples, based almost exlusively on authors' experience, detailed numerical graphical...
Although a family history of schizophrenia is the best-established risk factor for schizophrenia, environmental factors such as place and season birth may also be important.
The clinical course of alcoholic cirrhosis, a condition with high mortality, has not been well described. We examined prevalence, risk, chronology, and mortality associated three complications cirrhosis: ascites, variceal bleeding, hepatic encephalopathy. followed population-based cohort 466 Danish patients diagnosed cirrhosis in 1993–2005, starting from the date hospital diagnosis ending August 2006. Data were extracted medical charts during follow-up period. Risk calculated using...
The experience of a patient in survival study may be modelled as process with two states and one possible transition from an “alive” state to “dead” state. In some studies, however, the partitioned into or more intermediate (transient) states, each which corresponding particular stage illness. such multi-state models can used model movement patients among various states. these issues, interest include estimation progression rates, assessing effects individual risk factors, rates prognostic...
Typically, regression models for competing risks outcomes are based on proportional hazards the crude hazard rates. These estimates often do not agree with impressions drawn from plots of cumulative incidence functions each level a risk factor. We present technique which directly. The method is pseudovalues jackknife statistic constructed curve. used in generalized estimating equation to obtain model parameters. study properties this estimator and apply effect alternative donors relapse...
Abstract A common problem encountered in many medical applications is the comparison of survival curves. Often, rather than entire curves, interest focused on at a fixed point time. In most cases, naive test based difference estimates used for this comparison. note, we examine performance alternatives to test. These include tests number transformations function and generalized linear model pseudo‐observations. The type I errors power these variety sample sizes are compared by Monte Carlo...
<h3>Importance</h3> Results from animal and human studies suggest that lithium in therapeutic doses may improve learning memory modify the risk of developing dementia. Additional preliminary subtherapeutic levels, including microlevels lithium, influence cognition. <h3>Objective</h3> To investigate whether incidence dementia general population covaries with long-term exposure to drinking water. <h3>Design, Setting, Participants</h3> This Danish nationwide, population-based, nested...
The evidence on mental health during COVID-19 evolved fast, but still little is known about the long-lasting impact of sequential lockdowns. We examine changes in young people's from before to initial and second more prolonged lockdown, whether women those with pre-existing depressive symptoms were disproportionally impacted.Participants reported indicators an ongoing 18-year data collection Danish National Birth Cohort a survey, including 8 points: 7 1 year post. Changes quality life (QoL),...
Risk prediction models need thorough validation to assess their performance. Validation of for survival outcomes poses challenges due the censoring observations and varying time horizon at which predictions can be made. This article describes measures evaluate potential improvement in decision making from based on Cox proportional hazards regression. As a motivating case study, authors consider composite outcome recurrence or death (the "event") patients with breast cancer after surgery....
We describe a bootstrap investigation of the stability Cox proportional hazards regression model resulting from analysis clinical trial azathioprine versus placebo in patients with primary biliary cirrhosis. have considered to refer both choice variables included and, more importantly, predictive ability model. In stepwise analyses 100 samples using 17 candidate variables, most frequently selected were those original analysis, and no other important variable was identified. Thus there reason...
This paper deals with the competing risks model as a special case of multi-state model. The properties are reviewed and contrasted to so-called latent failure time approach. relation between right-censoring is discussed regression analysis cumulative incidence function briefly reviewed. Two real data examples presented guide practitioner given.
It has been suggested that lithium may have neuroprotective abilities, but it is not clear whether reduces the risk of dementia.To investigate continued treatment with dementia in a nationwide study.An observational cohort study linkage registers all patients prescribed and diagnosed as having Denmark from January 1, 1995, through December 31, 2005.We identified treated within community psychiatry, private specialist, general practices random sample 30% population. Subjects A total 16,238...
Objective: It is generally accepted that one of the most important predictors recurrence in depressive and bipolar disorders number previous episodes. However, very few studies have considered individual tendency toward analyses effect episodes on risk subsequent affective disorder. Method: Frailty models were used to estimate rate taking into account frailty recurrence. The study base consisted 406 patients, 186 patients with disorder 220 disorder, who admitted between 1959 1963 Psychiatric...