A5088039325- Acute Myocardial Infarction Research
- Cardiac electrophysiology and arrhythmias
- Cardiac Imaging and Diagnostics
- Cardiac Valve Diseases and Treatments
- Infective Endocarditis Diagnosis and Management
- Coronary Interventions and Diagnostics
- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiovascular Function and Risk Factors
- Aortic Disease and Treatment Approaches
- Cardiac pacing and defibrillation studies
- Antiplatelet Therapy and Cardiovascular Diseases
- ECG Monitoring and Analysis
- Venous Thromboembolism Diagnosis and Management
- Genetic Associations and Epidemiology
- Acute Ischemic Stroke Management
- Cardiac Structural Anomalies and Repair
- Lipoproteins and Cardiovascular Health
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Health and Mental Health
- Heart Failure Treatment and Management
- Heart Rate Variability and Autonomic Control
- Machine Learning in Healthcare
- Cardiac Arrest and Resuscitation
- Diabetes, Cardiovascular Risks, and Lipoproteins
Helsinki University Hospital
2025
Tampere University
2015-2024
Tampere University Hospital
2015-2024
University College Hospital at Westmoreland Street
2023
University College London
2023
University of Rochester Medical Center
2021
Society of Thoracic Surgeons
2020
NHS Tayside
2020
McMaster University
2016
Pirkanmaa Hospital District
2008-2013
It is unknown whether the preferred 1-stent bifurcation stenting approach with of main vessel (MV) and optional side branch using drug-eluting stents should be finalized by a kissing balloon dilatation (FKBD). Therefore, we compared strategies MV without FKBD.We randomized 477 patients lesion to FKBD (n=238) or no (n=239) after stenting. The primary end point was major adverse cardiac events: death, non-procedure-related index myocardial infarction, target revascularization, stent thrombosis...
Objective: Investigation of the clinical potential extensive phenotype data and machine learning (ML) in prediction mortality acute coronary syndrome (ACS). Methods: The value ML was analyzed a retrospective registry study 9066 consecutive ACS patients (January 2007 to October 2017). Main outcome six-month mortality. Prediction models were developed using two methods, logistic regression extreme gradient boosting (xgboost). fitted training set treated 2007-2014 2017 (81%, n = 7344) validated...
Background It is still uncertain whether coronary bifurcations with lesions involving a large side branch (SB) should be treated by stenting the main vessel and provisional of SB (simple) or routine two-stent techniques (complex). We aimed to compare clinical outcome after treatment in simple complex stent implantation. Methods The study was randomised, superiority trial. Enrolment required SB≥2.75 mm, ≥50% diameter stenosis both vessels, allowed lesion length up 15 mm. primary endpoint...
Abstract With over 17 million annual deaths, cardiovascular diseases (CVDs) dominate the cause of death statistics. CVDs can deteriorate quality life drastically and even sudden death, all while inducing massive healthcare costs. This work studied state-of-the-art deep learning techniques to predict increased risk in CVD patients, building on electronic health records (EHR) 23,000 cardiac patients. Taking into account usefulness prediction for chronic disease a period six months was...
The aim of this study was to compare the risk prosthetic valve endocarditis (PVE) in patients with transcatheter aortic replacement (TAVR) or surgical (SAVR).The FinnValve registry included data from 6,463 consecutive who underwent TAVR (n=2,130) SAVR (n=4,333) a bioprosthesis 2008 2017. PVE defined according modified Duke criteria. In study, incidence 3.4/1,000 person-years after TAVR, and 2.9/1,000 SAVR. competing analysis there no significant difference between over an eight-year...
The aim of this study was to evaluate the incidence and prognostic impact paravalvular regurgitation (PVR) on outcome after transcatheter (TAVR) surgical aortic valve replacement (SAVR) for stenosis.The nationwide FinnValve registry included data 6463 consecutive patients who underwent TAVR (n = 2130) or SAVR 4333) with a bioprosthesis treatment stenosis during 2008-2017. PVR at discharge 4-year mortality herein investigated.The rate mild 21.7% 5.2% SAVR. moderate-to-severe 3.7% 0.7% After...
Sudden cardiac arrests (SCA) and sudden deaths (SCD) are believed to account for a large proportion of due cardiovascular causes. The purpose this study is provide comprehensive information on the epidemiology SCAs SCDs after acute coronary syndrome.The incidence SCA (including SCDs) was studied retrospectively among 10,316 consecutive patients undergoing invasive evaluation syndrome (ACS) between 2007 2018 at Tays Heart Hospital (sole provider specialized care catchment area over 0.5...
Deviation of the PR segment is a common but often ignored ECG finding in acute myopericarditis, seems to be rare phase ST elevation myocardial infarction (STEMI). Since rapid bedside differential diagnosis myopericarditis and STEMI essential, we decided assess diagnostic power depressions patients presenting with elevations emergency room.Thirty-four consecutive 46 fulfilling criteria for were included. The first recorded room was analyzed focus on segment. diagnoses ascertained clinical...
<h3>Importance</h3> Transcatheter aortic valve replacement (TAVR) has been shown to be a valid alternative surgical (SAVR) in patients at high operative risk with severe stenosis (AS). However, the evidence of benefits and harms TAVR low is still scarce. <h3>Objective</h3> To compare short-term midterm outcomes after SAVR low-risk AS. <h3>Design, Setting, Participants</h3> This retrospective comparative effectiveness cohort study used data from Nationwide Finnish Registry Surgical Aortic...
Aims. We examined the prognostic impact of eight different intraventricular conduction delays (IVCD) in standard electrocardiogram (ECG) a community cohort.Methods and results. Data were collected from 6299 Finnish individuals. During mean 8.2 years (interquartile range 8.1 to 8.3) follow-up 640 subjects died (10.2%); 277 (4.4%) cardiovascular deaths. For both sexes, all-cause mortality was higher with IVCD than those without. In Cox regression analysis after adjustment for age gender,...
Home dialysis has been associated with better patient survival compared to in-center hemodialysis. Finland over 40 years of experience home dialysis. Despite sustained efforts, the prevalence decreased in last decade. We aimed explore barriers expanding treatments from healthcare providers' and patients' perspectives. This is qualitative research, based on an electronic semi-structured survey directed nephrologists, nephrology nurses, associations. The development contemplated main shown a...
Background: The significance of ST‐segment depression in acute coronary syndrome has been the subject debate for many decades. Studies indicate that different manifestations ST/T changes may have significantly prognostic implications. Methods and Results: We studied correlation 12‐lead electrocardiography recorded during pain, to clinical angiographic findings in‐hospital prognosis, patients with non‐ST‐elevation elevated troponin levels. Fifty consecutive could be differentiated into two...