- Coronary Interventions and Diagnostics
- Peripheral Artery Disease Management
- Cardiac Imaging and Diagnostics
- Acute Myocardial Infarction Research
- Vascular Procedures and Complications
- Cerebrovascular and Carotid Artery Diseases
- Venous Thromboembolism Diagnosis and Management
- Abdominal Trauma and Injuries
- Cardiac Valve Diseases and Treatments
- Biliary and Gastrointestinal Fistulas
- Pediatric Hepatobiliary Diseases and Treatments
- Cardiovascular Function and Risk Factors
- Multiple and Secondary Primary Cancers
- Cancer Diagnosis and Treatment
- Spine and Intervertebral Disc Pathology
- Cardiac Structural Anomalies and Repair
- Intracranial Aneurysms: Treatment and Complications
- Coronary Artery Anomalies
- Cardiac, Anesthesia and Surgical Outcomes
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Antiplatelet Therapy and Cardiovascular Diseases
- Kawasaki Disease and Coronary Complications
- Gallbladder and Bile Duct Disorders
- Gastrointestinal Tumor Research and Treatment
- Spinal Fractures and Fixation Techniques
Azienda Ospedaliera Universitaria Policlinico "Paolo Giaccone" di Palermo
2020-2025
University of Palermo
2020-2025
All India Institute of Medical Sciences
2024
Saint Laurent Polyclinique
2023
Istituto Ortopedico Galeazzi
2023
Bocconi University
2023
CTO Hospital
2023
AOL (United States)
2023
Maria Eleonora Hospital
2009-2017
Regione Siciliana
2015
Chronic total occlusions (CTOs) of coronary arteries can be found in the context chronic or acute syndromes; sometimes they are an incidental finding those apparently healthy individuals undergoing imaging for preoperative risk assessment. Recently, invasive management CTOs has made impressive progress due to sophisticated preinterventional assessment, including advanced non-invasive imaging, availability novel and dedicated tools CTO percutaneous intervention (PCI), experienced...
Percutaneous coronary interventions (PCI) of chronic total occlusions (CTO) have reached high procedural success rates thanks to dedicated equipment, evolving techniques, and worldwide adoption state-of-the-art crossing algorithms.
Importance Patients with high bleeding risk (HBR) have a poor prognosis, and it is not known if they may benefit from complete revascularization after myocardial infarction (MI). Objective To investigate the of physiology-guided vs culprit-only strategy in patients HBR, MI, multivessel disease. Design, Setting, Participants This was prespecified analysis Functional Assessment Elderly MI With Multivessel Disease (FIRE) randomized clinical trial data. FIRE an investigator-initiated,...
The FIRE trial (Functional Assessment in Elderly Myocardial Infarction Patients With Multivessel Disease) enrolled 1445 older (aged ≥75 years) patients with myocardial infarction and multivessel disease Italy, Spain, Poland. were randomized to physiology-guided complete revascularization or treatment of the only culprit lesion. Physiology-guided significantly reduced ischemic adverse events at 1 year. This prespecified analysis investigated changes between 2 study groups angina status,...
Introduction The use of contemporary drug-eluting stents (DES) has significantly improved outcomes patients with coronary artery disease (CAD) undergoing percutaneous intervention (PCI). However, concerns exist regarding the long-term proinflammatory effects durable polymer coatings used in most DES, potentially leading to adverse events. First-generation polymer-free stent technologies, such as sirolimus- and probucol-eluting (PF-SES), have shown an excellent safety efficacy profile. aim...
Background: Residual stenosis and dissections occurring after femoro-popliteal percutaneous transluminal angioplasty (PTA) can compromise vessel patency should therefore be properly dealt with at the time of index procedure. Sometimes, decision to optimize PTA result may challenging because it is based on evidence from angiography which, as a bi-dimensional imaging technique, has well-known limitations. Objectives: The objective this study was evaluate whether an intraoperative Doppler...
To evaluate the effectiveness of psychiatric counseling in reducing rate development side effects antiviral therapy with interferon-α and ribavirin among study participants compared standard clinical monitoring alone.Interferon-α is used to treat chronic hepatitis C. Interferons may induce adverse events that usually, but not always, reverse within a few days after end therapy.Two hundred eleven patients C, genotype 1b were treated peginterferon for 48 weeks prospective trial. Two groups...
Abstract Background Gender‐specific data addressing percutaneous coronary intervention (PCI) of chronic total occlusion (CTO) in female patients are scarce and based on small sample size studies. Aims We aimed to analyze gender‐differences regarding in‐hospital clinical outcomes after CTO‐PCI. Methods Data from 35,449 enrolled the prospective European Registry CTOs were analyzed. The primary outcome was comparison procedural success rate two cohorts (women vs. men), defined as a final...
To describe through emblematic images rare but clinically relevant carotid artery stenting complications that occurred at two high-volume centres for (CAS).
Background: Gastrointestinal bleeding (GIB) is a common complication of left ventricular assist device (LVAD) support. The UTAH risk score (UBRS) the only dedicated GIB prediction model, but its efficacy has not been confirmed in an external validation cohort. Furthermore, reliability other scores, such as ARC-HBR and HASBLED, never tested this specific population. This study aims to validate UBRS compare accuracy with HASBLED scores. Methods: Major adverse events (MAEs) 75 consecutive...
Abstract Objectives To investigate the correlation between quantitative flow ratio (QFR), Pd/Pa, diastolic hyperemia‐free (DFR) and fractional reserve (FFR, gold standard) in non‐culprit lesion (NCL) of patients with non ST‐segment elevation myocardial infarction (NSTEMI). Background The non‐hyperemic pressure (NHPR) angiography‐based indexes have been developed to overcome limitation use FFR. Methods Between January December 2019, 184 NCL from 116 NSTEMI underwent physiologic assessment...
Background: The aim of the study is to evaluate subclinical alterations cardiac mechanics detected using speckle-tracking echocardiography and compare these data with coronary angiography indices used during in a population patients diagnosed ischemia no obstructive artery (INOCA) microvascular angina (MVA). Methods: included 85 admitted our center between November 2019 January 2022 who were INOCA compared control group 70 healthy patients. A collection anamnestic complete cardiovascular...