Luca Fileti

ORCID: 0000-0002-0754-9739
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About
Contact & Profiles
Research Areas
  • Acute Myocardial Infarction Research
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Coronary Interventions and Diagnostics
  • Venous Thromboembolism Diagnosis and Management
  • Atrial Fibrillation Management and Outcomes
  • Peripheral Artery Disease Management
  • Cardiac Imaging and Diagnostics
  • Vascular Procedures and Complications
  • COVID-19 and healthcare impacts
  • Platelet Disorders and Treatments
  • Cardiac Health and Mental Health
  • Inflammatory mediators and NSAID effects
  • Cardiac Valve Diseases and Treatments
  • Neurofibromatosis and Schwannoma Cases
  • Infective Endocarditis Diagnosis and Management
  • Myeloproliferative Neoplasms: Diagnosis and Treatment
  • Cardiac tumors and thrombi
  • Cardiac Structural Anomalies and Repair
  • Aortic Disease and Treatment Approaches
  • Chronic Disease Management Strategies
  • Blood Coagulation and Thrombosis Mechanisms
  • Cardiac Arrest and Resuscitation
  • Lipoproteins and Cardiovascular Health
  • Paraoxonase enzyme and polymorphisms

Ospedale "Santa Maria delle Croci" di Ravenna
2020-2024

Associazione Nazionale Medici Cardiologi Ospedalieri
2023

Ospedale Santa Maria
2018-2021

Azienda Unità Sanitaria Locale Della Romagna
2021

Arcispedale Sant'Anna
2010-2015

Cardiovascular Institute of the South
2009-2012

Fondazione Salvatore Maugeri
2010

The benefit of complete revascularization in older patients (≥75 years age) with myocardial infarction and multivessel disease remains unclear.In this multicenter, randomized trial, we assigned who were undergoing percutaneous coronary intervention (PCI) the culprit lesion to receive either physiology-guided nonculprit lesions or no further revascularization. Functionally significant identified by pressure wire angiography. primary outcome was a composite death, infarction, stroke, any at 1...

10.1056/nejmoa2300468 article EN New England Journal of Medicine 2023-08-26

Aims The purpose of this study was to verify the impact on number and characteristics coronary invasive procedures for acute syndrome (ACS) two hub centers with cardiac catheterization facilities, during first month lockdown following COVID-19 pandemic. Materials methods Procedural data ACS patients admitted between 10 March April 2020 were compared those same period 2019. Results We observed a 23.4% reduction in admissions 2020, decrease both ST-elevation myocardial infarction (STEMI)...

10.2459/jcm.0000000000001101 article EN Journal of Cardiovascular Medicine 2020-10-01

Abstract Aims The present analysis from the Functional Assessment in Elderly Myocardial Infarction Patients with Multivessel Disease (FIRE) trial aims to explore significance of pre-admission physical activity and assess whether benefits physiology-guided complete revascularization apply consistently sedentary active older patients. Methods results aged 75 years or more myocardial infarction (MI) multivessel disease were randomized receive culprit-only strategy. primary outcome was a...

10.1093/eurjpc/zwae069 article EN European Journal of Preventive Cardiology 2024-03-07

Abstract Objectives To investigate the correlation between quantitative flow ratio (QFR), Pd/Pa, diastolic hyperemia‐free (DFR) and fractional reserve (FFR, gold standard) in non‐culprit lesion (NCL) of patients with non ST‐segment elevation myocardial infarction (NSTEMI). Background The non‐hyperemic pressure (NHPR) angiography‐based indexes have been developed to overcome limitation use FFR. Methods Between January December 2019, 184 NCL from 116 NSTEMI underwent physiologic assessment...

10.1002/ccd.29380 article EN Catheterization and Cardiovascular Interventions 2020-11-19

Objective The study was designed to: (1) confirm safety and feasibility of mini-invasive radial balloon aortic valvuloplasty (BAV); (2) assess its impact in terms quality life frailty; (3) evaluate whether changes frailty after BAV are associated with death patients undergoing transcatheter valve implantation (TAVI). Methods 330 16 Italian centres were prospectively included. primary endpoint the occurrence major minor Valve Academic Research Consortium (VARC)-2 bleeding. Secondary endpoints...

10.1136/heartjnl-2020-318548 article EN Heart 2021-02-24

Antiplatelet therapy is the cornerstone of treatment for patients with acute coronary syndromes and in those who are undergoing percutaneous intervention (PCI). Clopidogrel, a second-generation thienopyridine antiplatelet agent, currently used to prevent vascular complications atherothrombotic patients, stent thrombosis PCI, long-term prevention cardiovascular cerebrovascular events. Unfortunately, despite clopidogrel, some continue have This may be due part suboptimal response drug, minimal...

10.3909/ricm12s1s0001 article EN Reviews in Cardiovascular Medicine 2011-01-20

<b><i>Objective:</i></b> We sought to demonstrate that the combination of a local vasodilator (verapamil), modern materials, patent hemostasis, and intravenous anticoagulant only in case percutaneous coronary intervention, as compared default heparin administration after sheath insertion, may optimize combined endpoint, including radial artery oc­clusion (RAO), spasm (RAS), access site complication. <b><i>Methods:</i></b> This is prospective,...

10.1159/000488852 article EN Cardiology 2018-01-01

Atherosclerosis is a systemic disease that can involve different arterial districts. Traditionally, the focus of cardiologists has been on diagnosis and treatment atherosclerotic coronary artery (CAD). However, atherosclerosis localization in other districts increasingly common associated with an increased risk CAD and, more generally, adverse cardiovascular events. Although term peripheral (PAD) commonly refers to lower limbs, this document, accordance European Society Cardiology...

10.1714/4244.42205 article EN PubMed 2024-04-01

Over the last 20 years epidemiology of acute coronary syndromes (ACS) has significantly changed, affecting both and post-acute phases. In particular, although progressive reduction in in-hospital mortality, trend post-hospital mortality was found to be stable or increasing. This at least part attributed improved short-term prognosis due interventions phase, which ultimately have increased population survivors high risk relapse. Thus, while hospital management ACS shown great progress terms...

10.1714/4026.40010 article EN PubMed 2023-05-01

Abstract This is a case of 71 year-old man, symptomatic for heart failure (NYHA II class), with recent weight loss and occurrence arthralgia. In the last month episodes non sustained ventricular tachycardia were observed. Transthoracic echocardiography showed dilated left ventricle reduced ejection fraction (30%) presence an apical cyst (dimensions 33×36 mm), no doppler signal inside. No relevant valvular diseases found. The first hypothesis was cystic echinococcosis localization, but...

10.1093/eurheartjsupp/suac121.122 article EN European Heart Journal Supplements 2022-12-14

In patients with an indication for oral anticoagulation (OAC) warfarin, the management of OAC peri-procedure percutaneous coronary intervention (PCI) is still not fully defined. To investigate clinical practice and outcomes associated continuation vs interruption OAC, or without bridging low-molecular-weight heparin (LMWH), we examined database observational, prospective, multicenter Italian WAR-STENT registry.The registry was conducted in 2008-2010 37 centers included 411 consecutive 157...

10.1714/3502.34884 article EN PubMed 2021-01-01
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