- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Acute Myocardial Infarction Research
- Cardiac Valve Diseases and Treatments
- Venous Thromboembolism Diagnosis and Management
- Infective Endocarditis Diagnosis and Management
- Peripheral Artery Disease Management
- Coronary Artery Anomalies
- Antiplatelet Therapy and Cardiovascular Diseases
- Vascular Procedures and Complications
- Atrial Fibrillation Management and Outcomes
- Cardiac Structural Anomalies and Repair
- Central Venous Catheters and Hemodialysis
- Kawasaki Disease and Coronary Complications
- Aortic Disease and Treatment Approaches
- Aortic aneurysm repair treatments
- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
- Mechanical Circulatory Support Devices
- Cardiac, Anesthesia and Surgical Outcomes
- Vascular anomalies and interventions
- Cardiac tumors and thrombi
- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular Function and Risk Factors
Hospital Universitario La Paz
2019-2025
Hospital La Paz Institute for Health Research
2020-2025
Centro de Investigación en Red en Enfermedades Cardiovasculares
2020-2025
Instituto de Salud Carlos III
2022-2025
Centro de Investigación Biomédica en Red
2022-2025
Centre for Biomedical Network Research on Rare Diseases
2023
Hospital General Universitario de Ciudad Real
2014-2022
Research Institute Hospital 12 de Octubre
2013-2017
Hospital Universitario HM Madrid
2015
Hospital Universitario 12 De Octubre
2010-2014
The benefit of complete revascularization in older patients (≥75 years age) with myocardial infarction and multivessel disease remains unclear.In this multicenter, randomized trial, we assigned who were undergoing percutaneous coronary intervention (PCI) the culprit lesion to receive either physiology-guided nonculprit lesions or no further revascularization. Functionally significant identified by pressure wire angiography. primary outcome was a composite death, infarction, stroke, any at 1...
Coronary calcification negatively affects the safety and effectiveness of percutaneous coronary intervention. There is a lack randomized comparisons among different plaque modification techniques. The aim this study was to compare rotational atherectomy (RA), excimer laser angioplasty (ELCA), intravascular lithotripsy (IVL) for treatment patients with calcified stenosis. Patients moderate severe lesions were randomly assigned intervention RA, IVL, or ELCA. primary endpoint percentage stent...
Intravascular lithotripsy (IVL) has demonstrated effectiveness in the treatment of calcified lesions selected patients with stable coronary disease.
ABSTRACT Background The therapeutic management of patients with multivessel disease and severe left ventricular dysfunction is complex controversial. Aims aim this study was to analyze the clinical outcomes changes in ejection fraction (LVEF) at least one chronic total occlusion (CTO) undergoing percutaneous coronary intervention (PCI) hemodynamic support provided by Impella. Methods Retrospective, multicenter enrolling artery CTO who required mechanical circulatory Impella, from January...
Parkinson's disease (PD) patients have most frequently heart failure. The cause of this increased prevalence is not known. We designed a study to assess the cardiac function and structure in with PD compared control group.Methods: Cross-sectional 50 healthy matched controls. performed electro echocardiograms all measurements were blind. In addition, we neurological assessment.Results: had higher left ventricular mass index (114.2 ± 38.4 vs. 94.1 26.4 g/m2; P = 0.003) atrial volume (30.1 7.9...
Background: There are few data on the prognostic significance of wall motion score index compared with left ventricle ejection fraction after an acute myocardial infarction. Our objective was to compare them hyperacute phase. Methods: Transthoracic echocardiograms were performed in 352 consecutive patients infarction, first 48 hours admission and before hospital discharge (median 56.3 (48.2–83.1)). We evaluated ability ventricular predict combined endpoint (mortality rehospitalization for...
Use of intravascular lithotripsy (IVL) for treating peri-stent calcification is increasing. However, this indication remains 'off-label'. We aimed to investigate the efficacy and clinical outcomes in-stent IVL. Patients from five European centers who underwent IVL were included between 2019 2023. Demographic, clinical, procedural follow-up data collected electronic hospital records. Angiographic intracoronary imaging (ICI) analyzed in a centralized core-laboratory. Of 101 patients (71.2 ±...
Intravascular lithotripsy (IVL) combined with rotational atherectomy (RA), known as Rotatripsy, is used to treat severe coronary artery calcification (CAC), though data on efficacy, midterm safety and use sequence limited. We aimed identify indicators for Rotatripsy assess its success rates, both acutely at 1-year follow-up.
BACKGROUND: Stent underexpansion is a significant challenge in percutaneous coronary intervention, critically impacting patient outcomes. While excimer laser angioplasty (ELCA) and intravascular lithotripsy (IVL) are increasingly used to address this issue, their full impact on the integrity of drug-eluting stents remains unclear, raising concerns about safety efficacy. METHODS: This vitro study assessed effects ELCA IVL structural using scanning electron microscopy. Nine stents, 5 Onyx...
Transradial access (TRA) is the preferred approach for percutaneous coronary intervention (PCI), associated with improved patient comfort, lower vascular complications and mortality compared to transfemoral access. However, TRA presents challenges such as radial artery spasm (RAS), occlusion (RAO), anatomical variability that have driven development of sheathless approach. This meta-analysis evaluates efficacy safety a dedicated system strategy versus conventional sheath-based techniques in...
To evaluate the prevalence and one-year prognosis associated with frailty in a contemporary cohort of older patients non-ST-elevation acute coronary syndrome (NSTEACS). The IMPACT-TIMING-GO registry (IMPACT Time Intervention Myocardial Infarction Non-ST seGment elevation. ManaGement Outcomes) prospectively included 1020 NSTEACS undergoing invasive angiography between April May 2021. For this sub-study, ≥ 65 years were selected. Frailty was assessed according to FRAIL scale. We studied...