- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Cardiac Valve Diseases and Treatments
- Acute Myocardial Infarction Research
- Atrial Fibrillation Management and Outcomes
- Cardiac Structural Anomalies and Repair
- Cerebrovascular and Carotid Artery Diseases
- Antiplatelet Therapy and Cardiovascular Diseases
- Peripheral Artery Disease Management
- Cardiac Arrhythmias and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiovascular Effects of Exercise
- Cardiovascular Function and Risk Factors
- Cardiac electrophysiology and arrhythmias
- Mechanical Circulatory Support Devices
- Vascular Procedures and Complications
- Infective Endocarditis Diagnosis and Management
- Cardiac and Coronary Surgery Techniques
- Aortic aneurysm repair treatments
- Cardiac pacing and defibrillation studies
- Venous Thromboembolism Diagnosis and Management
- Aortic Disease and Treatment Approaches
- Cardiovascular Disease and Adiposity
- Coronary Artery Anomalies
- Cardiomyopathy and Myosin Studies
Hospital Universitari i Politècnic La Fe
2016-2025
Centro de Investigación en Red en Enfermedades Cardiovasculares
2021-2025
Centro de Investigación Biomédica en Red
2021-2025
Instituto de Salud Carlos III
2024-2025
Leitat Technological Center
2022-2024
Hospital Universitario de La Princesa
2024
Northwell Health
2024
IRCCS Humanitas Research Hospital
2019-2023
Istituti di Ricovero e Cura a Carattere Scientifico
2019-2023
Instituto de Investigación Sanitaria La Fe
2018-2023
Colchicine has been utilized safely in a variety of cardiovascular clinical conditions. Among its potential mechanisms action is the non-selective inhibition NLRP3 inflammasome which thought to be major pathophysiologic component course patients with COVID-19. GRECCO-19 will prospective, randomized, open-labeled, controlled study assess effects colchicine COVID-19 complications prevention. Patients laboratory confirmed SARS-CoV-2 infection (under RT PCR) and picture that involves temperature...
There is limited information regarding clinical characteristics and outcomes of patients with SARS-CoV-2 (COVID-19) disease presenting ST-segment elevation myocardial infarction (STEMI). In this multicenter retrospective study, we reviewed charts admitted symptomatic COVID-19 infection STEMI to a total 4 hospitals spanning Italy, Lithuania, Spain Iraq from February 1, 2020 April 15, 2020. A 78 were included in 49 (63%) whom men, median age 65 [58, 71] years, high comorbidity burden. During...
Abstract Aims There is a lack of evidence regarding the benefits β-blocker treatment after invasively managed acute myocardial infarction (MI) without reduced left ventricular ejection fraction (LVEF). Methods and results The tREatment with Beta-blockers myOcardial withOut fracTion (REBOOT) trial pragmatic, controlled, prospective, randomized, open-label blinded endpoint (PROBE design) clinical testing maintenance therapy in patients discharged MI or ST-segment elevation. Patients eligible...
There is a lack of evidence to guide treatment patients with concomitant indication for transcatheter aortic valve implantation (TAVI) and complex, high-risk percutaneous coronary intervention (PCI). We aimed assess different strategies PCI timing in this TAVI cohort. The ASCoP registry retrospectively included clinical both at least 1 criterion complex or PCI. primary endpoint was composite all-cause death unplanned rehospitalisation cardiovascular causes. secondary death, stroke, acute...
Equipment delivery in chronic total occlusion (CTO) percutaneous coronary intervention (PCI) can be challenging and it is associated with a higher risk of device entrapment. Data regarding the incidence entrapment during CTO PCI are lacking.
Use of intravascular lithotripsy (IVL) for treating peri-stent calcification is increasing. However, this indication remains 'off-label'. We aimed to investigate the efficacy and clinical outcomes in-stent IVL. Patients from five European centers who underwent IVL were included between 2019 2023. Demographic, clinical, procedural follow-up data collected electronic hospital records. Angiographic intracoronary imaging (ICI) analyzed in a centralized core-laboratory. Of 101 patients (71.2 ±...
This study empirically evaluates the quality of life (QOL) effects associated with hospital discharge among heart transplant candidates whose lives are maintained by left ventricular support systems (LVAS). Thirty-five LVAS inpatients (18 Novacor, 17 Thoratec) received structured QOL assessments approximately 1 month after device implant. Ten patients (8 2 were subsequently discharged to either home or a home-like outpatient facility where their was reassessed. The patients, before and...
Antithrombotic treatment (ATT) post-left atrial appendage occlusion (LAAO) remains controversial. Furthermore, most of the patients undergoing LAAO are at a very high bleeding risk.
Artificial Intelligence (AI) faces growing challenges from evolving data protection laws and enforcement practices worldwide. Regulations like GDPR CCPA impose strict compliance requirements on Machine Learning (ML) models, especially concerning personal use. These grant individuals rights such as correction deletion, complicating the training deployment of Large Language Models (LLMs) that rely extensive datasets. Public availability does not guarantee its lawful use for ML, amplifying...
Background/Objectives: Drug-eluting stents (DESs) remain the standard of treatment for patients with ST-elevation myocardial infarction (STEMI). However, complications such as stent thrombosis and in-stent restenosis still pose significant risks. Drug-coated balloons (DCBs) have emerged a promising alternative, but data this clinical scenario are scarce. The objective was to evaluate safety efficacy DCB culprit-lesion primary percutaneous coronary intervention (pPCI) in presenting STEMI its...