A5078126758- Nicotinic Acetylcholine Receptors Study
- Ion channel regulation and function
- Genetic diversity and population structure
- Marine Biology and Ecology Research
- Antimicrobial Peptides and Activities
- Receptor Mechanisms and Signaling
- Animal Behavior and Reproduction
- Genetic Associations and Epidemiology
- Chemical Synthesis and Analysis
- Herpesvirus Infections and Treatments
- Immune Response and Inflammation
- Marine Bivalve and Aquaculture Studies
- Insect-Plant Interactions and Control
- Ocean Acidification Effects and Responses
- Genomics and Phylogenetic Studies
- interferon and immune responses
- Hymenoptera taxonomy and phylogeny
- Maternal and Perinatal Health Interventions
- Marine Sponges and Natural Products
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Aquatic Invertebrate Ecology and Behavior
- Lipoproteins and Cardiovascular Health
- Marine Toxins and Detection Methods
- bioluminescence and chemiluminescence research
- Lepidoptera: Biology and Taxonomy
University of Utah
2002-2023
LDS Hospital
1995
Howard Hughes Medical Institute
1995
University of Montana
1980
Background Although both genetic and nongenetic factors contribute to the pathogenesis of coronary artery disease, identification specific lesions has lagged behind critical environmental risk factors. A reported association between myocardial infarction (MI) insertion/deletion (I/D) polymorphism angiotensin-converting enzyme (ACE) gene in European men suggests a role for this genomic region. However, generality remains be determined. It also is not clear at what stage disease progression...
Abstract The current geographical distribution of the ninespine stickleback ( Pungitius pungitius ) was shaped in large part by glaciation events Pleistocene epoch (2.6 Mya–10 Kya). Previous efforts to elucidate phylogeographical history North America have focused on a limited set morphological traits, some which are likely subject widespread convergent evolution, thereby potentially obscuring relationships among populations. In this study, we used genetic information from both mitochondrial...
Mitochondrial genes in animals are especially useful as molecular markers for the reconstruction of phylogenies among closely related taxa, due to generally high substitution rates. Several insect orders, notably Hymenoptera and Phthiraptera, show exceptionally rates mitochondrial evolution, which has been attributed parasitic lifestyle current or ancestral members these taxa. Parasitism hypothesized entail frequent population bottlenecks that increase evolution by reducing efficiency...
A specialized insulin was recently found in the venom of a fish-hunting cone snail, Conus geographus Here we show that many worm-hunting and snail-hunting cones also express insulins, this novel gene family has diversified explosively. Cone snails highly conserved their nerve ring; presumably conventional signaling is finely tuned to receptor, which evolves very slowly. By contrast, insulins diverge rapidly, apparently response biotic interactions with prey possibly cones' own predators...
BACKGROUND Because genetic factors are believed to contribute the etiology of coronary artery disease (CAD), it has been suggested that DNA polymorphisms at candidate loci might identify individuals high risk for developing disease. In this regard, apolipoprotein genes represent extremely promising because levels apolipoproteins and their associated lipoproteins a major factor CAD, rare dysfunctional mutations in these result significant CAD. To date, although some reports indicate with...
Many social behaviors are conditional, but behavioral comparisons between populations do not normally distinguish genetic and environmental causation. As a result, the opportunity to test predictions about evolution of strategic conditionality (genotype × environment interaction) is lost. We apply these concepts in an examination how interpopulation differences mean variance sex ratio have led allocation male effort mate guarding versus nonguarding genetically isolated soapberry bug Oklahoma...
Since branch lengths provide important information about the timing and extent of evolutionary divergence among taxa, accurate resolution history depends as much on length estimates recovery correct topology. However, empirical relationship between choice genes to sequence quality estimation remains ill defined. To address this issue, we evaluated accuracy estimated from subsets mitochondrial genome for a mammalian phylogeny with known subordinal relationships. Using maximum-likelihood...
To determine the risk of cesarean delivery for women who themselves were born via operative delivery. A linked data base was constructed between birth certificates individuals in Utah during 1947–1957 (parental cohort) and subsequently became a parent offspring 1970–1991 (offspring cohort). Parental cohort (cases) had been delivered operatively (cesarean delivery, mid- or high forceps) as well sibling by an procedure matched (1:2) with parental-cohort spontaneous vaginal (controls). Both...
The biology, feeding ecology and phylogenetic relationships of marine snails in the family Turridae remain poorly understood. Here we report our study on four deep-water species genus Gemmula, a major group this family. G. speciosa (Reeve 1843), sogodensis (Olivera 2005), kieneri (Doumet 1940) diomedea (Powell 1964) were collected at five different sites Philippines, their pattern distribution sites, behavior as well with each other members subfamily Turrinae investigated. radular morphology...
Abstract Among primates, susceptibility to yellow fever (YFV), a single-stranded (ss) RNA virus, ranges from complete resistance high susceptibility. Howler monkeys (genus Alouatta ) are the most susceptible YFV. In order identify -specific genetic factors that may be responsible for their susceptibility, we collected skin samples howler monkey museum specimens of species A. caraya and guariba clamitans . We compared rate nonsynonymous synonymous ( dN/dS changes Toll-like receptor (TLR) 7...