Marie Lebel

ORCID: 0000-0003-0150-0384
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About
Contact & Profiles
Research Areas
  • Lymphatic System and Diseases
  • Cutaneous lymphoproliferative disorders research
  • Insect and Arachnid Ecology and Behavior
  • Nail Diseases and Treatments
  • Angiogenesis and VEGF in Cancer
  • Oral Health Pathology and Treatment
  • Neurobiology and Insect Physiology Research
  • Invertebrate Immune Response Mechanisms
  • Developmental Biology and Gene Regulation

Japanese Foundation For Cancer Research
2022-2023

Université Claude Bernard Lyon 1
2022

Institut de Génomique Fonctionnelle de Lyon
2022

École Normale Supérieure de Lyon
2022

Centre National de la Recherche Scientifique
2022

Regenerating animals have the ability to reproduce body parts that were originally made in embryo and subsequently lost due injury. Understanding whether regeneration mirrors development is an open question most regenerative species. Here, we take a transcriptomics approach examine leg shows similar temporal patterns of gene expression as embryo, crustacean Parhyale hawaiensis. We find stereotypic expression. In contrast, dynamics during show higher degree variation related physiology...

10.1073/pnas.2119297119 article EN cc-by-nc-nd Proceedings of the National Academy of Sciences 2022-07-01

Abstract Purpose: Osteosarcoma, the most common bone malignancy in children, has a poor prognosis, especially when tumor metastasizes to lungs. Therefore, novel therapeutic strategies targeting both proliferation and metastasis of osteosarcoma are required. Podoplanin (PDPN) is expressed by various tumors associated with tumor-induced platelet activation via its interaction C-type lectin-like receptor 2 (CLEC-2) on platelets. We previously found that PDPN contributed growth through...

10.1158/1078-0432.ccr-21-4509 article EN cc-by-nc-nd Clinical Cancer Research 2022-04-05

<div>AbstractPurpose:<p>Osteosarcoma, the most common bone malignancy in children, has a poor prognosis, especially when tumor metastasizes to lungs. Therefore, novel therapeutic strategies targeting both proliferation and metastasis of osteosarcoma are required. Podoplanin (PDPN) is expressed by various tumors associated with tumor-induced platelet activation via its interaction C-type lectin-like receptor 2 (CLEC-2) on platelets. We previously found that PDPN contributed growth...

10.1158/1078-0432.c.6532485.v1 preprint EN 2023-03-31

<div>AbstractPurpose:<p>Osteosarcoma, the most common bone malignancy in children, has a poor prognosis, especially when tumor metastasizes to lungs. Therefore, novel therapeutic strategies targeting both proliferation and metastasis of osteosarcoma are required. Podoplanin (PDPN) is expressed by various tumors associated with tumor-induced platelet activation via its interaction C-type lectin-like receptor 2 (CLEC-2) on platelets. We previously found that PDPN contributed growth...

10.1158/1078-0432.c.6532485 preprint EN 2023-03-31
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