Clove mistletoe ( Dendrophthoe pentandra (L.) Miq.) is a semiparasitic plant that belongs to Loranthaceae family. was traditionally used for cancer treatment in Indonesia. In the present study, we examined cytotoxicity of clove leaves extracts against brine shrimps and conducted their antiproliferative activity on K562 (human chronic myelogenous leukemia) MCM-B2 (canine benign mixed mammary) cell lines vitro. The tested samples were water extract, ethanol fraction, ethyl acetate n-hexane...

Stres oksidatif merupakan salah satu penyebab penyakit jantung, aterosklerosis, dan kanker. Upaya untuk mengatasi stress diantaranya adalah penggunaan antioksidan alami. Flavonoid fenolik senyawa metabolit sekunder pada tanaman yang memiliki aktivitas sebagai antioksidan. Tanaman dipercaya dapat rumput Kebar. Rumput Kebar (Biophytum umbraculum) tumbuhan secara empiris banyak manfaat obat kesuburan wanita oleh masyarakat Kebar-Papua. Penelitian dilakukan bertujuan mengetahui potensi...

Guazuma ulmifolia is one of the common tropical plants that has long been used as a traditional medicine to reduce body weight slimming herbs and lower cholesterol in body. The leaves G. contain phenolics compound such flavonoids tannin contributes its biological activities. In this research, we determined content total phenolics, flavonoids, tannins, antioxidant activity, FTIR spectrum profile from four extracts leaves. extraction method study was stepwise maceration with different solvents...

Melastoma affine plant has effect on health such as curing wound and toothache, also an antimalarial drug. The fruit of this is purple probably contain secondary metabolite compounds phenols flavonoids. total amount both may be different in unripe ripe fruit. aims research were to analyze determine phenol flavonoid extract. samples used study fruits. Both extracted by three solvents (water, 70% ethanol, 96% ethanol) obtained 6 extracts. Based phytochemical test, each extract from contained...

Abstract. Khumaida N, Syukur M, Bintang Nurcholis W. 2019. Phenolic and flavonoid content in ethanol extract agro-morphological diversity of Curcuma aeruginosa accessions growing West Java, Indonesia. Biodiversitas 20: 656-663. is a rhizomatous medicinal plant with beneficial pharmacological activities. The aim this work was to analyze the agro-morphological, yield, phenolic ten C. which were collected from different locations Cultivation carried out open field Java Indonesia using...

Spirulina is one of the microalgae containing nutrients used as functional food and in theraupetic (active compound). Bioactive compound has antihyperglycemic activity or antidiabetes activity. Diabetes mellitus a major health problem world. The research about potential antihyperglicemic important to do. cultivation was conducted laboratory using flask aquarium completed with non-stop aeration. Measurement in-vivo mices that were fed biomass fusiformis Voronikhin phycocyanin. Blood glucose...

Objective: Curcuma aeruginosa Roxb. is wild-growing rhizome herb in Indonesia with interesting pharmacological activities.This study evaluated the variability of total phenolic, flavonoid contents and their antioxidant activities 20 Indonesian accessions C. aeruginosa.Methodology: Total phenolic were determined by spectrophotometrically Folin-Ciocalteu colorimetric method, respectively.Antioxidant activity was inhibition using 2,2ʼ-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging...

The excessive number of free radicals in human body could increase lipid peroxides and causes a variety degenerative diseases. Piper crocatum is plant containing natural chemicals that may have an antioxidant ability to inhibit fatty acid oxidation reduce radicals, however, there no published scientific reports up now. Therefore, the objective this research study ethanol extract P. as antioxidant. leaves (25 g) were extracted with 100 ml 70% ethanol. Antioxidant activity was measured by...

Crude aqueous, 70% ethanol and 96% extracts from different part of rhizome Curcuma aeruginosa RoxB., namely primary (PR), secondary (SR) tertiary (TR) were screened for phytochemical compounds using qualitative methods, antioxidant activity 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical cytotoxicity brine shrimp lethality test (BSLT).The crude extract PR (IC50, 437.07 µg/ ml) had stronger DPPH scavenging compared to the other rhizomes C. aeruginosa.None parts found be more active than...

To evaluate the contents of curcuminoids (curcumin, demethoxycurcumin and bisdemethoxycurcumin) cytotoxic activity in ethanolic extracts 20 Curcuma aeruginosa RoxB. (C. aeruginosa) accessions collected from regions Indonesia. Curcuminoid compounds were investigated by high performance liquid chromatography with standards, was evaluated brine shrimp lethality test. Curcuminoids, curcumin, bisdemethoxycurcumin C. varied 0.01% to 1.95% coefficient variation (CV) 27.36%, 1.45% a CV 30.56%, 0.47%...

The antimicrobial activity of garlic extract against Gram-positive and Gram-negative bacterial isolates was well studied. However, reports on antibacterial some pathogenic bacteria in animals Indonesia, are still limited. Therefore, the aim this study to evaluate water ethanol extracts Salmonella typhimurium chickens, Streptococcus agalactie, Escherichia coli, Staphylococcus aureus causing mastitis dairy cows Indonesia. A filtrate fresh used determine S. at concentrations 5%, 10%, 20%, 30%,...

This study evaluated the free radical scavenging activity in ethanolic extracts from 20 accessions of Curcuma aeruginosa. The extract was investigated with 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical. IC50 values for DPPH ranged 89.81 to 505.65 µg mL-1. Based on values, twenty C. aeruginosa can be divided into three groups: strong (two accessions); moderate (seventeen and low (one accession) scavenger. Sukoharjo (SH) Muara Bungo (MB) showed promising antioxidant potential, thus these...

Piper crocatum and Cinnamomum burmannii formulations is known to be a new diabetes functional drink. Thus, its toxicological profile needs studied. At present, the formulation was evaluated for repeated dose toxicity study. The Sprague dawley albino rats were treated with P. C. (0, 630, 1260, 1890 mg/kg) administered orally period of 28 days in rats. effects on body weight, food water consumption, organ hematology, clinical biochemistry as well histology There no significant differences...

Phyllanthus acidus is an Indonesian plant belonging to the Euphorbiaccae family. Extraction of P. was performed using maceration method. Four-solvent extraction process by ethanol, 70% 30% and water used. The antioxidant activity from this extract determined 2,2-diphenyl-1-pikrilhidrazil (DPPH) cytotoxicity (biological potency extract) Brine Shrimp Lethality Test (BSLT) We found that yields samples ranging 1.13% 20.25%. ethanol showed highest yield, while lowest yield reported in fruit....

AbstrakBakteri endofit merupakan mikroorganisme menguntungkan yang berinteraksi dengan tanaman inang tanpa menyebabkan gangguan atau kerusakan pada tanaman.Beberapa studi menunjukkan bahwa bakteri tertentu dapat memproduksi senyawa kimia memiliki efek bagi kesehatan, terutama diisolasi dari obat.Binahong (Anredera cordifolia) dan Ketepeng Cina (Cassia alata) obat telah diketahui beberapa khasiat.Tujuan penelitian ini ialah mengisolasi mengkarakterisasi kedua tersebut melalui uji...

Coleus scutellarioides [L.] Benth. known as medicinal plant which contains antidiarhea and antimicrobial compounds. Extraction of bioactive compound from plants is not efficient because it needs a large biomass, therefore the one appropiate ways using endophytic bacteria. The purpose this research was to isolate test antibacterial activity bacteria against two pathogenic i.e Eschericia coli Staphylococcus aureus. A total 22 isolates were obtained Based on test, 13 able inhibit growth E. 15...

Alzheimer’s is a progressive and neurodegenerative disease that mainly affects people aged 65 years older. The pathophysiology of possibly related to the depletion neurotransmitter acetylcholine (ACh) due beta-amyloid plaques neurofibrillary tangles. Secondary metabolites found in cinnamon bark (Cinnamomum burmannii) have potential as anticholinesterases treat symptoms. This study aimed identify potency bioactive compounds from AChE inhibitors silico through analysis binding energy,...

Indonesia presently has the fourth largest diabetic mellitus prevalence of all countries in world. In a previous study, mixture extract Piper crocatum leaves and Cinnamomum burmannii bark showed vitro antihyperglycemic activity. It acted as inhibitor a-glucosidase enzyme had no toxic effect when it was administered orally to male female rats for 28 days. present extracts P. C. were used observe activity induced with streptozotocin. Mixture given Sprague Dawley at various doses 16 The results...