A5066410623- Retinal Diseases and Treatments
- Erythrocyte Function and Pathophysiology
- Vascular Malformations Diagnosis and Treatment
- Pancreatic function and diabetes
- Retinal and Macular Surgery
- Adenosine and Purinergic Signaling
- Retinoids in leukemia and cellular processes
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
Second Affiliated Hospital of Xi'an Jiaotong University
2023-2024
Purpose To investigate the expression, source, role, and mechanism of Fetuin-B (FETUB) in diabetic retinopathy (DR).
The purpose of this study was to investigate the correlation between insulin and Fetuin-B (FETUB) influence FETUB on signaling pathway in diabetic retinopathy (DR).
Aim. Pirfenidone (PFD), an antifibrotic drug, has various beneficial functions such as antioxidant, antifibrotic, and anti-inflammatory effects. This study aimed to explore the molecular mechanisms underlying how PFD modulates retinal pigment epithelial (RPE) cells involved in neovascularization subretinal fibrosis. Methods. ARPE-19 cell lines were treated with transforming growth factor-beta 2 (TGF-β2) alone or combination PFD. RPE viability, a consequence of use, was determined by CCK-8...