A5053509566- Plant Molecular Biology Research
- Plant Stress Responses and Tolerance
- Photosynthetic Processes and Mechanisms
- Plant-Microbe Interactions and Immunity
- Legume Nitrogen Fixing Symbiosis
- Plant nutrient uptake and metabolism
- Plant Gene Expression Analysis
- Plant Reproductive Biology
- Polymer-Based Agricultural Enhancements
- RNA Research and Splicing
- GABA and Rice Research
- Polysaccharides and Plant Cell Walls
- Cancer Genomics and Diagnostics
- Financial Markets and Investment Strategies
- Auditing, Earnings Management, Governance
- RNA modifications and cancer
- Plant Genetic and Mutation Studies
- SARS-CoV-2 detection and testing
- Axon Guidance and Neuronal Signaling
- SARS-CoV-2 and COVID-19 Research
- Advanced biosensing and bioanalysis techniques
- MicroRNA in disease regulation
- Ubiquitin and proteasome pathways
- Pancreatic function and diabetes
- Plant Pathogenic Bacteria Studies
Jiangxi Agricultural University
2017-2024
Renmin University of China
2017-2023
Ministry of Education of the People's Republic of China
2021-2022
Northwest University
2021-2022
Cedars-Sinai Medical Center
2017-2020
Shenzhen University
2015-2019
Nanjing Agricultural University
2012-2015
University Medical Center New Orleans
2011
Tulane University
2011
University of California, Los Angeles
2006-2010
In mammals, cadmium is widely considered as a non-genotoxic carcinogen acting through methylation-dependent epigenetic mechanism.Here, the effects of Cd treatment on DNA methylation patten are examined together with its effect chromatin reconfiguration in Posidonia oceanica.DNA level and pattern were analysed actively growing organs, under short-(6 h) long-(2 d or 4 d) term low (10 mM) high (50 doses Cd, Methylation-Sensitive Amplification Polymorphism technique an immunocytological...
Abstract Background MicroRNAs (miRNAs) are a class of short, endogenous non-coding small RNAs that have ability to base pair with their target mRNAs induce degradation in plants. miR394a/b conserved and its gene LCR ( LEAF CURLING RESPONSIVENESS ) encodes an F-box protein S KP1- C ullin/ DC53- F -box) but whether involved regulation plant response abscisic acid (ABA) abiotic stresses is unknown. Results Mature miR394 precursor shown be slightly induced by ABA. By contrast, expression...
The present study identified Arabidopsis miR394 and its target, an F-box (SKP1-Cullin/CDC53-F-box) gene At1g27340 (here referred to as LEAF CURLING RESPONSIVENESS, LCR), for regulation of leaf curling-related morphology. loss-of-function lcr mutants exhibit pleiotropic defects with semi-dwarfism, altered shape a shorter stem. Overexpression miR394-resistant version LCR under the 35S promoter (35S:m5LCR) target mimicry MIM394 resulted in curled-down defect. Conversely, transgenic plants...
Insulin receptors are abundant in the central nervous system, but their roles remain elusive. Here we show that insulin receptor functions axon guidance. The Drosophila (DInR) is required for photoreceptor-cell (R-cell) axons to find way from retina brain during development of visual system. DInR as a guidance adapter protein Dock/Nck. This function independent Chico, substrate (IRS) homolog.
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SWEET (Sugars Will Eventually be Exported Transporter) proteins mediate the translocation of sugars across cell membranes and play crucial roles in plant growth development as well stress responses. In this study, a total 25 genes were identified from Medicago truncatula genome divided into four clades based on phylogenetic analysis. The MtSWEET are distributed unevenly M. chromosomes, eight 12 segmentally tandemly duplicated, respectively. Most contain five introns encode with seven...
Melatonin is an important bioactive molecule in plants. Two synthetases, N-acetylserotonin methyltransferase (ASMT) and serotonin N-acetyltransferase (SNAT) are involved the final two steps of melatonin synthesis. participates responses to a variety biotic abiotic stresses plants, but few studies have addressed roles endogenous pathogen resistance. We investigated role resistance Botrytis cinerea infection Arabidopsis thaliana model system. Plant lines that overexpressed ASMT or SNAT through...
Nucleotidyl transferases (NTPs) are common in eukaryotes and play a crucial role nucleotide modifications at the 3' end of RNA. In plants, NTPs can regulate RNA stability by influencing modifications, which turn affect plant growth, development, stress responses, disease resistance. Although functions NTP family members have been extensively studied Arabidopsis, rice, maize, there is limited knowledge about genes soybeans. this study, we identified 16 soybeans, including two subfamilies (G1...
Leukemia- and lymphoma-associated (LLA) chromosomal rearrangements are critical in the process of tumorigenesis. These genetic alterations also important biological markers diagnosis, prognosis, treatment hematopoietic malignant diseases. To detect presence or absence these healthy individuals, sensitive nested RT-PCR analyses were performed on a large number peripheral blood samples for selected including MLL partial tandem duplications (PTDs), BCR-ABL p190, p210, MLL-AF4, AML1-ETO,...
The ubiquitination pathway regulates growth, development, and stress responses in plants, the U-box protein family of ubiquitin ligases has important roles this pathway. Here, 64 putative proteins were identified Medicago truncatula genome. In addition to conserved motif, other functional domains, such as ARM, kinase, KAP, WD40 also detected. Phylogenetic analysis M. grouped them into six subfamilies, chromosomal mapping synteny analyses indicated that tandem segmental duplications may have...
In late December 2019, an outbreak of a novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, China. Data on the routes transmission to Los Angeles, California, US West Coast epicenter for disease 2019 (COVID-19), and subsequent community spread are limited.To determine SARS-CoV-2 Southern California elucidate local within Angeles metropolitan area.This case series included 192 consecutive patients with reverse transcription-polymerase chain reaction (RT-PCR)...
Stress associated proteins (SAPs) play important roles in developmental processes, responses to various stresses and hormone stimulation plants. However, little is known about the SAP gene family Medicago truncatula. In this study, a total of 17 MtSAP genes encoding A20/AN1 zinc-finger were characterized. Out these genes, 15 distributed over all 8 chromosomes at different densities, two segmental duplication events detected. The phylogenetic analysis their orthologs from Arabidopsis rice...
Both endocrine and exocrine pancreatic cells arise from pancreatic-duodenal homeobox 1 (pdx1)-positive progenitors. The molecular mechanisms controlling cell fate determination subsequent proliferation, however, are poorly understood. Unlike cells, less is known about specification. We report here the identification characterization of a novel determinant gene, differentiation proliferation factor (exdpf), which highly expressed in progenitors differentiated developing pancreas zebrafish....
Rapeseed (Brassica napus) is one of the most important vegetable oil crops worldwide. Abiotic stresses such as salinity are great challenges for its growth and productivity. DEAD-box RNA helicase 6 (RH6) a subfamily member superfamily 2 (SF2), which plays crucial roles in plant development. However, no report available on RH6 regulating abiotic stress response. This study investigated function regulatory mechanism BnRH6. BnRH6 was targeted to nucleus cytoplasmic processing body (P-body),...
The matrix metalloproteinase (MMP) family of proteins degrades extracellular (ECM) components as well processes cytokines and growth factors. MMPs are involved in regulating ECM homeostasis both normal physiology disease pathophysiology. Here we report the critical roles mmp23b zebrafish liver development. Mmp23b was initially identified a gene linked to genomic locus an enhancer trap transgenic line which green fluorescent protein (GFP) expression restricted developing liver. Follow-up...
Abstract Background The U-box gene family encodes E3 ubiquitin ligases involved in plant hormone signaling pathways and abiotic stress responses. However, there has yet to be a comprehensive analysis of the maize ( Zea mays L.) its responses stress. Results In this study, 85 proteins were identified classified into four subfamilies based on phylogenetic analysis. addition conserved domain, we additional functional domains, including Pkinase, ARM, KAP Tyr by analyzing motifs structures....