A5036259948- Dermatology and Skin Diseases
- Complementary and Alternative Medicine Studies
- Olfactory and Sensory Function Studies
- Health Policy Implementation Science
- Asthma and respiratory diseases
- Food Allergy and Anaphylaxis Research
- Contact Dermatitis and Allergies
- Allergic Rhinitis and Sensitization
- Eosinophilic Esophagitis
University of Bristol
2018-2023
Care UK (United Kingdom)
2023
Abstract Objectives To determine the clinical effectiveness and cost of including emollient bath additives in management eczema children. Design Pragmatic randomised open label superiority trial with two parallel groups. Setting 96 general practices Wales western southern England. Participants 483 children aged 1 to 11 years, fulfilling UK diagnostic criteria for atopic dermatitis. Children very mild who bathed less than once weekly were excluded. Interventions intervention group prescribed...
To our knowledge, there are no trials comparing emollients commonly used for childhood eczema. We aimed to compare the clinical effectiveness and safety of four main emollient types: lotions, creams, gels, ointments.We did a pragmatic, individually randomised, parallel group, phase 4 superiority trial in 77 general practice surgeries England. Children aged between 6 months 12 years with eczema (Patient Orientated Eczema Measure [POEM] score >2) were randomly assigned (1:1:1:1; stratified by...
Childhood eczema is very common. Treatment often includes emollient bath additives, despite there being little evidence of their effectiveness.To determine the clinical effectiveness and cost-effectiveness additives in management childhood eczema.Pragmatic, randomised, open-label, multicentre superiority trial with two parallel groups.Ninety-six general practices Wales, west England southern England. Invitation by personal letter or opportunistically.Children aged between 12 months years...
Emollients are recommended for children with eczema (atopic eczema/dermatitis). A lack of head-to-head comparisons the effectiveness and acceptability different types emollients has resulted in a 'trial error' approach to prescribing.
Patient-reported outcomes measures in clinical trials ensure that evaluations of effectiveness focus on are important to patients. In relapsing-remitting conditions, such as eczema, repeated measurements may allow a more accurate reflection disease burden and treatment effect than less frequent measurements. We asked parents/carers children with eczema taking part trial bath emollients complete weekly questionnaires for 16 weeks. The objective this study was determine the acceptability...
Abstract Background Eczema is a common childhood condition, causing dry and itchy skin which can be difficult to manage. We have been undertaking eczema food allergy research address previously prioritised questions. obtained funding trial novel approaches reach diverse audiences raise awareness of eczema, research, public involvement in research. Methods This paper reflects on two engagement events held collaboration with stakeholders settings ethnic diversity East Bristol, UK. invited...