Johannes Kersten

ORCID: 0000-0003-0165-9977
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About
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Research Areas
  • Cardiac Imaging and Diagnostics
  • Cardiovascular Function and Risk Factors
  • Cardiovascular Effects of Exercise
  • Viral Infections and Immunology Research
  • Long-Term Effects of COVID-19
  • Chemotherapy-induced cardiotoxicity and mitigation
  • Advanced MRI Techniques and Applications
  • Coronary Interventions and Diagnostics
  • Acute Myocardial Infarction Research
  • Cardiomyopathy and Myosin Studies
  • Cardiovascular Disease and Adiposity
  • Cardiac Health and Mental Health
  • Cardiovascular and exercise physiology
  • COVID-19 Clinical Research Studies
  • Cardiac pacing and defibrillation studies
  • Thermal Regulation in Medicine
  • Cardiac Valve Diseases and Treatments
  • Pulmonary Hypertension Research and Treatments
  • Ocular Infections and Treatments
  • Electron Spin Resonance Studies
  • Infectious Encephalopathies and Encephalitis
  • Philosophy and Historical Thought
  • Fibromyalgia and Chronic Fatigue Syndrome Research
  • Inflammatory Myopathies and Dermatomyositis
  • Antifungal resistance and susceptibility

Universität Ulm
2020-2025

University Hospital Ulm
2021-2024

American Institute of Ultrasound in Medicine
2023

(1) Background: Long COVID syndrome refers to long-term sequelae of the novel viral disease, which occur even in patients with initially mild disease courses. However, there is still little evidence actual organic consequences and their frequency, no standardized workup diagnose long yet. In this study, we aim determine efficiency a stepwise diagnostic approach for reconvalescent COVID-19 cardiopulmonary symptoms. (2) Methods: The included three steps. first step, focus was on broad...

10.3390/jcm10173782 article EN Journal of Clinical Medicine 2021-08-24

Abstract After acute infection with the SARS-CoV-2 virus, a considerable number of patients remains symptomatic pathological changes in various organ systems. This study aimed to relate physical and mental burden symptoms long COVID findings somatic evaluation. In persistent three months after we assessed health status using SF-36 questionnaire. The cohort was dichotomised by results (upper two quartiles vs. lower quartiles) compared regard transthoracic echocardiography, body...

10.1038/s41598-022-12839-5 article EN cc-by Scientific Reports 2022-05-25

Abstract Background The five-year survival rate of breast cancer patients has improved due to early detection and advances in oncological therapy. However, these modern treatments also mean that more may experience the long-term effects their therapy therapy-related cardiac dysfunction (CTRCD). To date, there is no established primary prevention minimise occurrence CTRCD. Purpose Cardiac Health Breast Cancer (CHiB) study a two-arm, single-center, randomised (1:1) controlled trial...

10.1093/ehjci/jeae333.405 article EN European Heart Journal - Cardiovascular Imaging 2025-01-01

(1) Background: Dyspnea is one of the most frequent symptoms among post-COVID-19 patients. Cardiopulmonary exercise testing (CPET) key to a differential diagnosis dyspnea. This study aimed describe and classify patterns cardiopulmonary dysfunction in patients, using CPET. (2) Methods: A total 143 symptomatic patients were included study. All underwent CPET, including oxygen consumption, slope minute ventilation CO2 production, capillary blood gas testing, evaluated for signs limitation by...

10.3390/ijerph191811421 article EN International Journal of Environmental Research and Public Health 2022-09-10

This study aims to investigate normal changes throughout aging of the heart in cardiac magnetic resonance (CMR) imaging healthy volunteers. While type 2 diabetes mellitus is a frequent finding elderly population, also influence this circumstance otherwise persons part our study.In prospective single-center trial, 75 subjects distinct age groups and 10 diabetics were enrolled. All underwent functional, flow sensitive, native T2- T1-mapping 1.5T CMR scanner.No differences right left...

10.4250/jcvi.2022.0021 article EN Journal of Cardiovascular Imaging 2022-01-01

Whether symptoms during COVID-19 contribute to impaired left ventricular (LV) function remains unclear. We determine LV global longitudinal strain (GLS) between athletes with a positive test (PCAt) and healthy control (CON) relate it COVID-19. GLS is determined in four-, two-, three-chamber views assessed offline by blinded investigator 88 PCAt (35% women) (training at least three times per week/>20 MET) 52 CONs from the national or state squad (38% median of two months after The results...

10.3390/jcdd10050189 article EN cc-by Journal of Cardiovascular Development and Disease 2023-04-23

Abstract Background Breast cancer is a common and increasingly treatable disease. However, survivors have significantly elevated risk of cardiac events afterwards. This study aimed to characterise changes during cardiotoxic therapy using cardiovascular magnetic resonance (CMR) imaging. Methods involved 34 patients with histologically proven breast planned therapy. All underwent CMR before starting therapy, 6 12 months thereafter. The protocol included volumetric functional analyses,...

10.1007/s10554-023-02996-7 article EN cc-by The International Journal of Cardiovascular Imaging 2023-11-25

Abstract Background Cardiac involvement has been described in idiopathic inflammatory myopathies (IIM), including non-specific ECG and echocardiographic findings. Aim of our study was to evaluate myocardial deformation parameters IIM correlate them with late gadolinium enhancement (LGE) findings using cardiac magnetic resonance imaging (CMR). Methods Forty-seven consecutive patients histologically proven were included into study. Twenty-five healthy volunteers used as a control group. All...

10.1007/s10554-020-02020-2 article EN cc-by The International Journal of Cardiovascular Imaging 2020-09-17

The ongoing COVID-19 pandemic demands a series of measures and, above all, the vaccination substantial proportion population. Acute myocarditis is rare complication widely used mRNA-based vaccines.We present case four patients (three men and one woman, 16 to 47 years old) with acute pericarditis/myocarditis 3 17 days after mRNA vaccination. They presented chest pain, fever, flu-like symptoms. Diagnosis was made based on synopsis clinical presentation, elevated levels troponin T NT-proBNP,...

10.3389/fmed.2022.836620 article EN cc-by Frontiers in Medicine 2022-02-14

During the COVID-19 pandemic, in anticipation of a demand surge for high-care hospital beds, many hospitals postponed non-emergency interventions cardiac patients.The aim this study was to assess outcomes patients whose had been deferred during pandemic.Patients intervention cancelled between March 19th and April 30th, 2020 were included (study group). All considered as deferrable according current recommendations. Patients' after 12 months compared seasonal control group who underwent 2019...

10.1007/s00392-022-02032-z article EN cc-by Clinical Research in Cardiology 2022-05-23

Background: This prospective single-center study sought to investigate the impact of cardiovascular magnetic resonance (CMR) on diagnosis myocarditis, with special attention given absolute T1 values and defined cutoff values. Methods: All patients referred our center suspicion an inflammatory myocardial disease were diagnosed by a consensus expert consortium blinded CMR findings. Classical Lake Louise criteria then used confirm or change diagnosis. Results: Of total 149 patients, 15 acute...

10.3390/jcm9123810 article EN Journal of Clinical Medicine 2020-11-25

(1) Background: Segmented Cartesian Cardiovascular magnetic resonance (CMR) often fails to deliver robust assessment of cardiac function in patients with arrhythmia. We aimed assess the performance a tiny golden-angle spiral real-time CMR sequence at 1.5 T for left-ventricular (LV) volumetry irregular heart rhythm; (2) Methods: validated against standard breath-hold segmented 32 patients, whom 11 presented End-diastolic volume (EDV), end-systolic (ESV), stroke (SV), and ejection fraction...

10.3390/jcm11082088 article EN Journal of Clinical Medicine 2022-04-08

AbstractBackground Myocardial deformation parameters have been shown to yield early detection of pathological changes in chronic heart failure (CHF). Aim our study was evaluate myocardial under optimal medical therapy (OMT) CHF patients.Methods patients were examined longitudinally with two cardiac magnetic resonance imaging (CMR) examinations at a median time interval 140 days. Left and right ventricular volumes quantified, analysis performed using feature tracking, respectively.Results 57...

10.1080/00015385.2023.2246202 article EN Acta Cardiologica 2023-08-22

Abstract Background Breast cancer is a common and increasingly treatable disease. However, survivors have significantly elevated risk of cardiac events afterwards. This study aimed to characterise changes during cardiotoxic therapy using cardiovascular magnetic resonance (CMR) imaging. Methods involved 34 patients with histologically proven breast planned therapy. All underwent CMR before starting therapy, 6 12 months thereafter. The protocol included volumetric functional analyses,...

10.1101/2023.04.21.23288954 preprint EN medRxiv (Cold Spring Harbor Laboratory) 2023-04-24

Fusarium (F.) species are ubiquitous filamentous fungi that may cause various opportunistic infections, especially in patients who immunocompromised. A rare manifestation of disseminated fusariosis affects the aortic valve and results invasive aortitis, which poses a significant challenge for clinicians diagnosis treatment. Here, we report case patient, aged 54 years, is immunocompromised, presenting initially with keratitis chorioretinitis both eyes new endovascular mass. Positron emission...

10.1016/j.ijid.2023.05.069 article EN cc-by-nc-nd International Journal of Infectious Diseases 2023-06-05

Abstract Chronic total occlusion (CTO) is a common finding in patients with known or suspected coronary artery disease and has distinctive role these patients’ quality of life. However, there still lack evidence correct patient selection for percutaneous intervention (PCI). From July 2017 to August 2020, 68 successful PCI CTO previous viability by cardiovascular magnetic resonance imaging (CMR) were prospectively included this single-centre observational study. Of patients, 62 underwent...

10.1007/s10554-023-02916-9 article EN cc-by The International Journal of Cardiovascular Imaging 2023-07-12

Background/Objectives: Myocardial involvement has been observed in athletes following SARS-CoV-2 infection. It is unclear if these changes are due to myocardial damage per se or an interruption training. The aim of this study was assess cardiac function and structure elite before after infection (INFAt) compare them a group healthy controls (CON). Methods: Transthoracic echocardiography performed 32 athletes, including 16 INFAt (median 21.0 (19.3–21.5) years, 10 male) (t0) 52 days (t1) mild...

10.3390/biomedicines12102310 article EN cc-by Biomedicines 2024-10-11

The incidence of breast cancer has increased from 900 000 to 2.3 million new annual cases over the last 25 years. 5-year survival rate markedly risen 90% worldwide due significant therapeutic advancements. Longer in patients with means more may experience long-term effects their treatments, including therapy-related cardiac dysfunction (CTRCD). To date, there is no established primary prevention minimise CTRCD. Cardiac Health Breast Cancer study a two-arm, single-centre, randomised...

10.1136/bmjsem-2024-002265 article EN cc-by-nc BMJ Open Sport & Exercise Medicine 2024-11-01
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