Objectives Methodologically, to assess the feasibility of participant recruitment and retention, as well missing data in studying mental disorder among children newly diagnosed with chronic physical conditions (ie, multimorbidity). Substantively, examine prevalence multimorbidity, identify sociodemographic correlates model influence multimorbidity on changes child quality life parental psychosocial outcomes over a 6-month follow-up. Design Prospective pilot study. Setting Two children’s...

Canada legalized recreational cannabis use for adults on October 17, 2018 with decision-makers emphasising the need to reduce among youth.We sought characterise trends of youth before and after legalization by relying a quasi-experimental design evaluating high school students in Alberta, British Columbia, Ontario, Québec who participated COMPASS prospective cohort study.Overall were examined using large repeat cross-sectional sample (n = 102,685) at two time points (16/17 17/18 years) one...

Abstract Objective The aim of this research was to examine the bidirectional association between self-reported symptoms mental disorder and physical activity among a large sample Canadian secondary school students over time. Methods Linked survey data were obtained from 28,567 grade 9 12 across Canada participating in two waves COMPASS Study (2017–18; 2018–19). Autoregressive cross-lagged models run reciprocal relationships moderate-to-vigorous (MVPA) depression (CESD-10) anxiety (GAD-7)....

The objective of this study was to examine associations between depression, anxiety and binge drinking among a large sample Canadian youth, while testing the moderating effect flourishing. This research uses data from Cannabis, Obesity, Mental health, Physical activity, Alcohol, Smoking, Sedentary Behaviour (COMPASS) (2012-2021) with size collecting on youth health behaviours within secondary schools.Cross-sectional SETTING: 14 schools across Ontario British Columbia, Canada.A grade 9-12...

ABSTRACT Objectives: The aim of this study was to investigate the sociodemographic, behavioural, and psychological characteristics students who reported using cannabis in school-year preceding legalization Canada. Methods: Data were derived from 36,884 attending 122 schools that participated year 6 (2017–2018) COMPASS Study, a large, prospective cohort administers questionnaires annually high across Multilevel logistic regression models used estimate odds past-year use among students....

Consumption of caffeinated energy drinks (CED) by youth is a public health priority, given the lack regulation and evidence for both short long-term effects CED use. Considering potential risks associated with excessive caffeine consumption, this paper examined consumption predictors use over time in large sample Canadian secondary school students participating COMPASS study. Using linked longitudinal data (n = 4949) from first three years study (2012/13 to 2014/15), logistic Generalized...

Little is known about gender differences in associations between weight control intentions and mental health adolescents. Our objective was to examine these a large sample of adolescent girls boys.Using data from Year 6 (2017-18) the COMPASS study (n = 57 324), we performed series multivariable linear regressions whether (gain, lose, stay same, no intention) were associated with depression, anxiety self-concept, while adjusting for relevant covariates including body mass index. Models...

Selection of appropriate study design and analytical methods is critical for producing robust research, as the approach used can ultimately shape results their interpretation. The objective this research was to examine how findings from a large repeat cross-sectional data system compare those sample longitudinal nested within same system, using milk alternative consumption case study. Overall, were consistent, article highlights strengths limitations both methodologies under examination....

Using data from two methodologically independent youth research studies in Canada, the Health Behaviour School-aged Children (HBSC) study and Cannabis, Obesity, Mental health, Physical activity, Alcohol, Smoking, Sedentary behaviour (COMPASS) study, objective of this was to compare associations between youth's mental health cannabis use across samples. similar indicators both studies, our goal affirm potential for nationally representative cross-sectional analyses replicate findings found a...

(1) Objective: To longitudinally assess food and beverages sold in vending machines secondary schools (grades 9–12) participating the COMPASS study (2015/2016 2018/2019) (2) to examine if patterns trends observed previous years (2012/2013 2014/2015) are consistent with lack of policy compliance Ontario Alberta, Canada. Methods: Policy was assessed through comparing nutritional information on drink (e.g., sports drinks) snack chocolate bars) products Program Memorandum (P/PM) 150 (required...

Our objective was to explore associations between indicators of more risky cannabis use (i.e., solitary use, frequent and younger age initiation) different modes smoking, vaping and/or edibles).Data were gathered from a large sample Canadian youth in Alberta, British Columbia, Ontario, Quebec who participated Year 8 (2019-20) the COMPASS study, reported using past year (n = 4,763). Generalized estimating equations used examine stratified by gender.Overall, 38% students multiple use....

In 1911 Addis noted that patients with haemophilia are unable to use prothrombin.This observation has been extended by Milstone (1948) and Quick (1947) the development latter of prothrombin consumption test its later modification (Quick Favre-Gilly, 1949).It hoped this would prove a diagnostic aid in recognition haemophilia, especially those cases where clotting time is within normal limits or only slightly prolonged.Recently such case came under at Toronto General Hospital.Case Report...

Objective: The objective of this research was to determine the school and community characteristics associated with milk alternative (MMA) consumption by Canadian youth. Methods: We analyzed self-reported data from 50,058 students participating in 2017-2018 wave COMPASS survey. used logistic linear regression analyses identify school- community-level factors meeting MMA guidelines, daily number servings consumed, respectively. Results: Student-level were more strongly than factors. Students...

Substance use behaviours have been found to cluster in youth, and cannabis has previously linked tobacco e-cigarette use. The objective of the current study was examine bidirectional associations between cannabis, e-cigarette, cigarette among a large sample Canadian secondary school students. A students grades 9–11 (n = 14,652) from Ontario Alberta, Canada who participated two waves COMPASS Study (Time 1 (T1): 2015–2016; Time 2 (T2): 2016–2017) identified. Autoregressive cross-lagged models...

This study examined how schools prioritize ten key health concerns among their student populations over time and whether schools' prioritization of alcohol other drug use (AODU) corresponds to students' substance behaviours cannabis legalization as a major policy change. Data were collected from sample secondary in Ontario, Canada across four years (2015/16-2018/19 [N2015/16 = 65, N2016/17 68, N2017/18 61 N2018/19 60]) part the COMPASS study. School-level prevalence between that did not AODU...

<p>The molecular and functional heterogeneity of pancreatic b-cells is well recognized, but the underlying mechanisms remain unclear. Pancreatic islets harbor a subset that co-express Tyrosine Hydroxylase (TH), an enzyme involved in synthesis catecholamines repress insulin secretion. Restriction TH+ within essential for appropriate function mice, such higher proportion these cells corresponds to reduced Here, we use as model dissect developmental control b-cell heterogeneity. We define...

<p>The molecular and functional heterogeneity of pancreatic b-cells is well recognized, but the underlying mechanisms remain unclear. Pancreatic islets harbor a subset that co-express Tyrosine Hydroxylase (TH), an enzyme involved in synthesis catecholamines repress insulin secretion. Restriction TH+ within essential for appropriate function mice, such higher proportion these cells corresponds to reduced Here, we use as model dissect developmental control b-cell heterogeneity. We define...

Introduction: To support schools in the implementation of evidence-based and context-appropriate programs for youth substance use prevention, knowledge users have expressed a need to better understand how are implemented. The objective this study was examine availability cannabis-specific global (ie, targeting multiple substances) secondary whether programming varied by school context pre-post-federal cannabis legalization. Methods: This used survey data provided administrators at 58 Ontario...