A5074230210- Immunodeficiency and Autoimmune Disorders
- Nail Diseases and Treatments
- Reproductive tract infections research
- Drug-Induced Adverse Reactions
- Genetic and rare skin diseases.
- T-cell and B-cell Immunology
- Autoimmune Bullous Skin Diseases
- Syphilis Diagnosis and Treatment
- Eosinophilic Disorders and Syndromes
- Chemotherapy-related skin toxicity
- Chronic Lymphocytic Leukemia Research
University of California, Irvine
2021-2023
Abstract: Enfortumab vedotin is an antibody–drug conjugate used for treatment of urothelial cancer. It has recently been associated with several reports Stevens Johnson syndrome/toxic epidermal necrolysis (TEN). In this report, we describe the case a 63-year-old man who developed widespread, near full–thickness desquamation, clinically mimicking TEN but histologic features toxic erythema chemotherapy. This distinction significant because it may have implications prognosis and treatment....
Tertiary syphilis may present a diagnostic challenge due to negative nontreponemal serologies in up 30% of cases and frequent lack identifiable spirochetes on histopathology or other direct detection tests. We report 2 round bodies staining with Treponema pallidum immunohistochemistry by light microscopy biopsies from cutaneous syphilitic gummata. In 1 case, the finding was validated 3 times independent laboratories; T. detected polymerase chain reaction biopsy sample. Spirochete have...
This case report describes a female teenager with mild eczema and patchy alopecia areata presenting severe headache, gastrointestinal distress, fatigue, arthralgias, skin eruption on bilateral extremities.